Neurotrophic factor therapy for Parkinson's disease (Q37796025)

23 August 2017

Neurotrophic factor therapy for Parkinson's disease (English)

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23 August 2017

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4

Jeffrey H Kordower

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23 August 2017

3

Roy A E Bakay

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23 August 2017

Suresh Babu Rangasamy

series ordinal

1

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PubMed ID

20887879

23 August 2017

Katherine Soderstrom

series ordinal

2

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23 August 2017

1 January 2010

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Progress in Brain Research

23 August 2017

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23 August 2017

184

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23 August 2017

237-264

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Functional recovery in hemiparkinsonian primates transplanted with polymer-encapsulated PC12 cells

23 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophins stimulate the release of dopamine from rat mesencephalic neurons via Trk and p75Lntr receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: a quantitative immunocytochemical study

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Localization of GDNF/neurturin receptor (c-ret, GFRalpha-1 and alpha-2) mRNAs in postnatal rat brain: differential regional and temporal expression in hippocampus, cortex and cerebellum

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

NMDA receptors mediate an early up-regulation of brain-derived neurotrophic factor expression in substantia nigra in a rat model of presymptomatic Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Nerve growth factor increases survival of dopaminergic graft, rescue nigral dopaminergic neurons and restores functional deficits in rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Transplantation of fetal kidney cells: neuroprotection and neuroregeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophic factors for the treatment of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Dopaminergic neurons protected from degeneration by GDNF gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor concentration dependently improves disability and motor activity in MPTP-treated common marmosets

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Inducible ablation of astrocytes shows that these cells are required for neuronal survival in the adult brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Astrocyte delivery of glial cell line-derived neurotrophic factor in a mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Long-term enhanced chromaffin cell survival and behavioral recovery in hemiparkinsonian rats with co-grafted polymer-encapsulated human NGF-secreting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Delivery of GDNF by an E1,E3/E4 deleted adenoviral vector and driven by a GFAP promoter prevents dopaminergic neuron degeneration in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Does neuronal expression of GDNF effectively protect dopaminergic neurons in a rat model of Parkinson's disease?

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

NGF in CNS: experimental data and clinical implications

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Functional regeneration in a rat Parkinson's model after intrastriatal grafts of glial cell line-derived neurotrophic factor and transforming growth factor beta1-expressing extra-adrenal chromaffin cells of the Zuckerkandl's organ.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Differential signaling of glial cell line-derived neurothrophic factor and brain-derived neurotrophic factor in cultured ventral mesencephalic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Differential actions of neurotrophins in the locus coeruleus and basal forebrain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Shedding light into the role of BDNF in the pharmacotherapy of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Trophic factor distribution predicts functional recovery in parkinsonian monkeys

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Morphological and functional effects of intranigrally administered GDNF in normal rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Functional recovery in parkinsonian monkeys treated with GDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

GDNF improves dopamine function in the substantia nigra but not the putamen of unilateral MPTP-lesioned rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophin-6 is a new member of the nerve growth factor family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Combined treatment of neurotrophin-3 gene and neural stem cells is ameliorative to behavior recovery of Parkinson's disease rat model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophins promote motor neuron survival and are present in embryonic limb bud.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Reduced BDNF mRNA Expression in the Parkinson's Disease Substantia Nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

The mesolimbic dopaminergic pathway is more resistant than the nigrostriatal dopaminergic pathway to MPTP and MPP+ toxicity: role of BDNF gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Postmortem analysis of adrenal-medulla-to-caudate autograft in a patient with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Structure-function relationships in the neurotrophin family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Emerging themes in structural biology of neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Clinically relevant effects of convection-enhanced delivery of AAV2-GDNF on the dopaminergic nigrostriatal pathway in aged rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Molecular cloning of a human gene that is a member of the nerve growth factor family

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Signal transduction by the neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Potentiated necrosis of cultured cortical neurons by neurotrophins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF is induced by wild-type alpha-synuclein but not by the two mutants, A30P or A53T, in glioma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Adenovirus-mediated transduction with human glial cell line-derived neurotrophic factor gene prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopamine depletion in striatum of mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

In vivo gene delivery of glial cell line--derived neurotrophic factor for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Lentiviral gene transfer to the nonhuman primate brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Cloning and expression of a novel neurotrophin, NT-7, from carp

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF and trkB mRNA expression in the rat hippocampus following entorhinal cortex lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6-hydroxydopamine-lesioned adult rats: comparison of intraventricular and intranigral delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

The nerve growth factor 35 years later

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Protective action of recombinant neurturin on dopaminergic neurons in substantia nigra in a Rhesus monkey model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

The therapeutic potential of neurotrophic factors in the treatment of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

NGF in experimental models of Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Nerve growth factor levels in Parkinson disease and experimental parkinsonian rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Two-site enzyme immunoassay for beta NGF applied to human patient sera

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor-transduced fibroblasts: production of BDNF and effects of grafting to the adult rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophin-3: a neurotrophic factor related to NGF and BDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged Rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Persephin, a novel neurotrophic factor related to GDNF and neurturin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Renal and neuronal abnormalities in mice lacking GDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophin-7: a novel member of the neurotrophin family from the zebrafish.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. One-year follow-up of first clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Protection of nigral neurons by GDNF-engineered marrow cell transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Association of a variation in the promoter region of the brain-derived neurotrophic factor gene with familial Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Trk receptors: mediators of neurotrophin action

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Treatment of Parkinson's disease with trophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Autopsy findings in a patient who had an adrenal-to-brain transplant for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Primary structure and biological activity of a novel human neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Control of the Neurotoxicity of 6-Hydroxydopamine by Intraneuronal Noradrenaline in Rat Iris

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Point source concentration of GDNF may explain failure of phase II clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor enhances function rather than survival of intrastriatal dopamine cell-rich grafts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF attenuates the effects of intrastriatal injection of 6-hydroxydopamine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophic factors in Alzheimer's and Parkinson's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Effect of nerve growth factor in adrenal autografts in parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Role of glutamate in neurodegeneration of dopamine neurons in several animal models of parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Rescue of basal forebrain cholinergic neurons after implantation of genetically modified cells producing recombinant NGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Pleiotropic functions of neurotrophins in development.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Circular dichroism and crosslinking studies of the interaction between four neurotrophins and the extracellular domain of the low-affinity neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

POLYMER-ENCAPSULATED PC12 CELLS: LONG-TERM SURVIVAL AND ASSOCIATED REDUCTION IN LESION-INDUCED ROTATIONAL BEHAVIOR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Signal transduction by the receptor tyrosine kinase Ret.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophin-4/5 promotes survival and differentiation of rat striatal neurons developing in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Neurotrophin-3 expressed in situ induces axonal plasticity in the adult injured spinal cord.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2984013-0

1 reference

7 January 2021

10.1016/S0079-6123(10)84013-0

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

20887879