New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation (Q37796596)

23 August 2017

New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation (English)

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23 August 2017

4

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23 August 2017

P Swietach

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23 August 2017

A Hulikova

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2

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23 August 2017

R D Vaughan-Jones

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3

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23 August 2017

language of work or name

English

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publication date

4 October 2010

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23 August 2017

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23 August 2017

29

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23 August 2017

6509-6521

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23 August 2017

50

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https://scigraph.springernature.com/pub.10.1038/onc.2010.455

23 August 2017

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Regulation of intracellular pH.

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Extracellular acidification elicits spatially and temporally distinct Ca2+ signals.

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Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.

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The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors

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Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes

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Facilitation of intracellular H(+) ion mobility by CO(2)/HCO(3)(-) in rabbit ventricular myocytes is regulated by carbonic anhydrase

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A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers

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Putative re-entrant loop 1 of AE2 transmembrane domain has a major role in acute regulation of anion exchange by pH

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pH nanoenvironment at the surface of single melanoma cells

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Novel chloride-dependent acid loader in the guinea-pig ventricular myocyte: part of a dual acid-loading mechanism

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Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

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Cell and environment interactions in tumor microregions: the multicell spheroid model

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Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin

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pH-Dependence of extrinsic and intrinsic H(+)-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H(+) compound.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Modelling intracellular H(+) ion diffusion

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Bicarbonate and pHi response

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

The histological structure of some human lung cancers and the possible implications for radiotherapy

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

MN antigen expression in normal, preneoplastic, and neoplastic esophagus: a clinicopathological study of a new cancer-associated biomarker

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The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer

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Electroneutral, HCO3(-)-independent, pH gradient-dependent uphill transport of Cl- by ileal brush-border membrane vesicles. Possible role in the pathogenesis of chloridorrhea

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Intrinsic H(+) ion mobility in the rabbit ventricular myocyte

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Extracellular H+ inactivation of Na(+)-H+ exchange in the sheep cardiac Purkinje fibre

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.455

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.455

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23 August 2017

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