Pharmacokinetic evaluation of idebenone (Q37800933)

23 August 2017

Pharmacokinetic evaluation of idebenone (English)

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23 August 2017

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ChEBI release 2020-05-28

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Claudia Becker

1

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23 August 2017

Katharine Bray-French

series ordinal

2

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23 August 2017

Juergen Drewe

series ordinal

3

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23 August 2017

language of work or name

English

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publication date

1 November 2010

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Expert Opinion on Drug Metabolism & Toxicology

23 August 2017

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23 August 2017

6

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23 August 2017

11

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23 August 2017

1437-1444

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Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade

23 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Clinical and genetic abnormalities in patients with Friedreich's ataxia

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Evolution of the Friedreich's ataxia trinucleotide repeat expansion: founder effect and premutations

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Friedreich ataxia: an overview

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Diagnosis and treatment of Friedreich ataxia: a European perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Molecular insights into Friedreich's ataxia and antioxidant-based therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone: an emerging therapy for Friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone in patients with Friedreich ataxia

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone treatment in paediatric and adult patients with Friedreich ataxia: long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Neurological, cardiological, and oculomotor progression in 104 patients with Friedreich ataxia during long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Friedreich's ataxia: idebenone treatment in early stage patients

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Oxidative stress in patients with Friedreich ataxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Heart hypertrophy and function are improved by idebenone in Friedreich's ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes: basic concepts, clinical phenotype, and therapeutic management of MELAS syndrome

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Idebenone improves cerebral mitochondrial oxidative metabolism in a patient with MELAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Long-term treatment with idebenone and riboflavin in a patient with MELAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Inherited mitochondrial optic neuropathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Leber's Hereditary Optic Neuropathy (LHON) with 14484/ND6 mutation in a North African patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Clinical and brain bioenergetics improvement with idebenone in a patient with Leber's hereditary optic neuropathy: a clinical and 31P-MRS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Remission of Leber's hereditary optic neuropathy with idebenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Primary-progressive multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Leigh and Leigh-like syndrome in children and adults

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: a long-term follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Mitochondrial structural and functional dynamics in Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

A controlled trial of idebenone in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Disposition of idebenone (CV-2619), a new cerebral metabolism improving agent, in rats and dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Metabolism of idebenone (CV-2619), a new cerebral metabolism improving agent: isolation and identification of metabolites in the rat and dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in brain mitochondria from rats and dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Pharmacokinetics and metabolism of idebenone in healthy male subjects

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Pharmacokinetic properties and metabolism of idebenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

Safety, Tolerability, and Pharmacokinetics of High-Dose Idebenone in Patients With Friedreich Ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2010.530656

10.1517/17425255.2010.530656

21 January 2018

Identifiers

DOI

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23 August 2017

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