Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations. (Q37724200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

review article

1 reference

title

Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

0 references

Cristina Parrado-Fernandez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Francisco J Alcain

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Jose M Villalba

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Monica Santos-Gonzalez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

1 April 2010

1 reference

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Expert Opinion on Investigational Drugs

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

535-554

1 reference

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30 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20367194%20AND%20SRC:MED&resulttype=core&format=json

Isolation of a quinone from beef heart mitochondria

30 January 2020

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Coenzyme Q reductase from liver plasma membrane: purification and role in trans-plasma-membrane electron transport

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Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol

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Three classes of ubiquinone analogs regulate the mitochondrial permeability transition pore through a common site

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Neutral magnesium-dependent sphingomyelinase from liver plasma membrane: purification and inhibition by ubiquinol

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Coenzyme Q10 affects expression of genes involved in cell signalling, metabolism and transport in human CaCo-2 cells

21 January 2018

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Effects of ubiquinol-10 on microRNA-146a expression in vitro and in vivo

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Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ

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Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis.

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Distribution and redox state of ubiquinones in rat and human tissues

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Primary coenzyme Q10 deficiency and the brain.

21 January 2018

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21 January 2018

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Regulation of ubiquinone metabolism

21 January 2018

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Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines.

21 January 2018

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Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.

21 January 2018

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Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics

21 January 2018

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Coenzyme Q10 administration and its potential for treatment of neurodegenerative diseases

21 January 2018

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Improvement in intestinal coenzyme q10 absorption by food intake

21 January 2018

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Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat.

21 January 2018

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Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers

21 January 2018

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Bioavailability of four oral coenzyme Q10 formulations in healthy volunteers

21 January 2018

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Relative bioavailability of two forms of a novel water-soluble coenzyme Q10.

21 January 2018

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Metabolism of coenzyme Q10: biliary and urinary excretion study in guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Evaluation of cytotoxicity of oils used in coenzyme Q10 Self-emulsifying Drug Delivery Systems (SEDDS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Increase of bioavailability of coenzyme Q(10) and vitamin E.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Safety assessment of coenzyme Q10 (CoQ10).

21 January 2018

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Evaluation of the mutagenic and genotoxic potential of ubiquinol.

21 January 2018

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Prolonged intake of coenzyme Q10 impairs cognitive functions in mice

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Cerebellar ataxia and coenzyme Q10 deficiency

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Mutations in coenzyme Q10 biosynthetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders

21 January 2018

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ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency

21 January 2018

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CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures

21 January 2018

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A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease

21 January 2018

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Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency

21 January 2018

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Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis

21 January 2018

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The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene

21 January 2018

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Coenzyme Q10 and vitamin E deficiency in Friedreich's ataxia: predictor of efficacy of vitamin E and coenzyme Q10 therapy.

21 January 2018

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The role of coenzyme Q10 in statin-associated myopathy: a systematic review

21 January 2018

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Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study

21 January 2018

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Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial.

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Redox status of coenzyme Q10 is associated with chronological age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q, oxidative stress and aging

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Activities of vitamin Q10 in animal models and a serious deficiency in patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 in neuromuscular and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Oxidative injury in the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Assessment of coenzyme Q10 tolerability in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Therapeutic role of coenzyme Q(10) in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Redox status of plasma coenzyme Q10 indicates elevated systemic oxidative stress in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients

21 January 2018

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Neuroprotective agents for clinical trials in ALS: a systematic assessment

21 January 2018

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Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III.

21 January 2018

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How do you treat patients with myalgia who take statins?

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543781003727495

Muscle coenzyme Q10 level in statin-related myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Statins, lack of energy and ubiquinone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Potential involvement of ubiquinone in myotonic dystrophy pathophysiology: new diagnostic approaches for new rationale therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Muscle coenzyme Q: a potential test for mitochondrial activity and redox status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10: an independent predictor of mortality in chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Supplemental ubiquinol in patients with advanced congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Pre-operative preparation for cardiac surgery utilising a combination of metabolic, physical and mental therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Targeting oxidative stress in surgery: effects of ageing and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

The role of oral coenzyme Q10 in patients undergoing coronary artery bypass graft surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Combined effect of coenzyme Q10 and fenofibrate on forearm microcirculatory function in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Oxidative stress, endothelial function and coenzyme Q10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Efficacy of coenzyme Q10 for improved tolerability of cancer treatments: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Effect of a nutritional supplement containing vitamin E, selenium, vitamin c and coenzyme Q10 on serum PSA in patients with hormonally untreated carcinoma of the prostate: a randomised placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Molecular Regulation of Cholesterol Biosynthesis: Implications in Carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 changes are associated with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 levels in human seminal fluid: diagnostic and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q10 and oxidative imbalance in Down syndrome: biochemical and clinical aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Coenzyme Q(10) and idebenone in the therapy of respiratory chain diseases: rationale and comparative benefits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Pharmacokinetics and metabolism of idebenone in healthy male subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Pharmacokinetic properties and metabolism of idebenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Disposition of idebenone (CV-2619), a new cerebral metabolism improving agent, in rats and dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: a long-term follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Idebenone improves cerebral mitochondrial oxidative metabolism in a patient with MELAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Long-term treatment with idebenone and riboflavin in a patient with MELAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Leber's hereditary optic neuropathy (LHON/11778) with myoclonus: report of two cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Idebenone protects hippocampal neurons against amyloid beta-peptide-induced neurotoxicity in rat primary cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Idebenone treatment fails to slow cognitive decline in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Clinical and genetic abnormalities in patients with Friedreich's ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Idebenone: an emerging therapy for Friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Idebenone treatment in paediatric and adult patients with Friedreich ataxia: long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Low-dose idebenone treatment in Friedreich's ataxia with and without cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Mitochondrial targeting of quinones: therapeutic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Idebenone in Friedreich's ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495

Cerebellar ataxia with coenzyme Q10 deficiency: Diagnosis and follow-up after coenzyme Q10 supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543781003727495