Alzheimer's disease genetics: current knowledge and future challenges (Q37801363)

23 August 2017

Alzheimer's disease genetics: current knowledge and future challenges (English)

1 reference

23 August 2017

0 references

Denise Harold

2

0 references

author name string

Paul Hollingworth

1

1 reference

23 August 2017

Lesley Jones

3

1 reference

23 August 2017

Michael J Owen

4

1 reference

23 August 2017

Julie Williams

5

1 reference

23 August 2017

language of work or name

English

0 references

publication date

19 October 2010

1 reference

International Journal of Geriatric Psychiatry

23 August 2017

1 reference

23 August 2017

26

1 reference

23 August 2017

793-802

1 reference

23 August 2017

8

1 reference

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

23 August 2017

1 reference

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

21 January 2018

1 reference

Genetic mapping in human disease

21 January 2018

1 reference

Predicting human height by Victorian and genomic methods

21 January 2018

1 reference

Genetics of Alzheimer's disease: recent advances

21 January 2018

1 reference

Neurobiology. Cholesterol--making or breaking the synapse

21 January 2018

1 reference

Evaluating coverage of genome-wide association studies

21 January 2018

1 reference

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

Multiple receptors mediate apoJ-dependent clearance of cellular debris into nonprofessional phagocytes

21 January 2018

1 reference

Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests.

21 January 2018

1 reference

Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease

21 January 2018

1 reference

The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease

21 January 2018

1 reference

Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

21 January 2018

1 reference

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

21 January 2018

1 reference

Genome-wide association studies in Alzheimer's disease

21 January 2018

1 reference

Brain cholesterol: long secret life behind a barrier.

21 January 2018

1 reference

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

21 January 2018

1 reference

Meta-analysis of linkage studies for Alzheimer's disease--a web resource

21 January 2018

1 reference

Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum

21 January 2018

1 reference

Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein

21 January 2018

1 reference

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

21 January 2018

1 reference

Bin1 ablation increases susceptibility to cancer during aging, particularly lung cancer.

21 January 2018

1 reference

Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

21 January 2018

1 reference

Problems of reporting genetic associations with complex outcomes

21 January 2018

1 reference

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

The interleukin 1beta gene promoter polymorphism (-511) acts as a risk factor for psychosis in Alzheimer's dementia.

21 January 2018

1 reference

Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates

21 January 2018

1 reference

Multipoint oligogenic analysis of age-at-onset data with applications to Alzheimer disease pedigrees

21 January 2018

1 reference

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

21 January 2018

1 reference

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

21 January 2018

1 reference

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.

21 January 2018

1 reference

The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family

21 January 2018

1 reference

Estimation of significance thresholds for genomewide association scans

21 January 2018

1 reference

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

21 January 2018

1 reference

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

1 reference

Role of Genes and Environments for Explaining Alzheimer Disease

21 January 2018

1 reference

Possible neuroprotective role of clusterin in Alzheimer's disease: a quantitative immunocytochemical study

21 January 2018

1 reference

Neuregulin-1 polymorphism in late onset Alzheimer's disease families with psychoses.

21 January 2018

1 reference

Common genetic variation and human traits

21 January 2018

1 reference

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

21 January 2018

1 reference

Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept

21 January 2018

1 reference

Evidence for CALM in directing VAMP2 trafficking

21 January 2018

1 reference

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 January 2018

1 reference

Progress in genome-wide association studies of human height.

21 January 2018

1 reference

Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis.

21 January 2018

1 reference

5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease.

21 January 2018

1 reference

21 January 2018

1 reference

Common variants at 30 loci contribute to polygenic dyslipidemia

21 January 2018

1 reference

The role of apolipoprotein E in Alzheimer's disease

21 January 2018

1 reference

Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice

21 January 2018

1 reference

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

21 January 2018

1 reference

Synthesis and functional analyses of nuclear clusterin, a cell death protein

21 January 2018

1 reference

Autoimmune diseases: insights from genome-wide association studies

21 January 2018

1 reference

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.

21 January 2018

1 reference

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.

21 January 2018

1 reference

Psychiatric medication and abnormal behavior as predictors of progression in probable Alzheimer disease

21 January 2018

1 reference

A HapMap harvest of insights into the genetics of common disease

21 January 2018

1 reference

Finding the missing heritability of complex diseases

21 January 2018

1 reference

Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

21 January 2018

1 reference

Distribution of clusterin in Alzheimer brain tissue

21 January 2018

1 reference

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

1 reference

Stress-induced transcription of the clusterin/apoJ gene.

21 January 2018

1 reference

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants

21 January 2018

1 reference

Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

21 January 2018

1 reference

On multiple-testing correction in genome-wide association studies

21 January 2018

1 reference

Clusterin: a forgotten player in Alzheimer's disease

21 January 2018

1 reference

Genetics of psychosis; insights from views across the genome

21 January 2018

1 reference

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling

21 January 2018

1 reference

Fear of harm, a possible phenotype of pediatric bipolar disorder: a dimensional approach to diagnosis for genotyping psychiatric syndromes

21 January 2018

1 reference

Evaluating and improving power in whole-genome association studies using fixed marker sets.

21 January 2018

1 reference

Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease

21 January 2018

1 reference

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

21 January 2018

1 reference

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

21 January 2018

1 reference

Epidemiology of and risk factors for psychosis of Alzheimer's disease: a review of 55 studies published from 1990 to 2003.

21 January 2018

1 reference

Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence

21 January 2018

1 reference

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

1 reference

Prevalence, correlates and course of behavioural and psychological symptoms of dementia in the population.

21 January 2018

1 reference

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

Genome-wide analysis of genetic loci associated with Alzheimer disease

21 January 2018

1 reference

The classical complement cascade mediates CNS synapse elimination

21 January 2018

1 reference

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

Catechol-O-methyltransferase haplotypes are associated with psychosis in Alzheimer disease.

21 January 2018

1 reference

Increased familial risk of the psychotic phenotype of Alzheimer disease.

21 January 2018

1 reference

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

1 reference

Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic

21 January 2018

1 reference

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

21 January 2018

1 reference

Value of genetic profiling for the prediction of coronary heart disease

21 January 2018

1 reference

Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease

21 January 2018

1 reference

Protective effects of NSAIDs on the development of Alzheimer disease

21 January 2018

1 reference

Genome-wide association studies: theoretical and practical concerns

21 January 2018

1 reference

Synaptic distribution of the endocytic accessory proteins AP180 and CALM

21 January 2018

1 reference

Complement activation in very early Alzheimer disease

21 January 2018

1 reference

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

21 January 2018

1 reference

Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy

21 January 2018

1 reference

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

21 January 2018

1 reference

Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease

21 January 2018

1 reference

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

21 January 2018

1 reference

7 January 2021

Genetics of psychosis in Alzheimer's disease: a review

1 reference

7 January 2021

1 reference

7 January 2021

Genome-wide scan of copy number variation in late-onset Alzheimer's disease

1 reference

7 January 2021

Genomewide association studies--illuminating biologic pathways

1 reference

7 January 2021

SP-40,40, a protein involved in the control of the complement pathway, possesses a unique array of disulphide bridges

1 reference

7 January 2021

Genetic risk prediction--are we there yet?

1 reference

7 January 2021

Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis

1 reference

7 January 2021

Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease

1 reference

7 January 2021

Identifiers

DOI

10.1002/GPS.2628

1 reference

23 August 2017

1 reference