Genetic variations in toll-like receptor pathway genes influence asthma and atopy (Q37805608)

23 August 2017

Genetic variations in toll-like receptor pathway genes influence asthma and atopy (English)

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23 August 2017

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R Tesse

1

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PubMed ID

21039600

23 August 2017

R C Pandey

series ordinal

2

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PubMed ID

21039600

23 August 2017

M Kabesch

series ordinal

3

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23 August 2017

8 October 2010

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23 August 2017

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23 August 2017

66

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3

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307-316

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The global burden of asthma: executive summary of the GINA Dissemination Committee report

23 August 2017

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Pathogenesis of allergic airway inflammation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

A cell biological view of Toll-like receptor function: regulation through compartmentalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

A toll-like receptor that prevents infection by uropathogenic bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Of mice and man: TLR11 (finally) finds profilin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Pattern recognition receptors and inflammation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Toll-like receptor signalling

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The danger within: endogenous danger signals, atopy and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Variation matters: TLR structure and species-specific pathogen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The role of NOD-like Receptors in shaping adaptive immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

NOD1 variation, immunoglobulin E and asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

NOD-like receptors: ancient sentinels of the innate immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

In utero and postnatal maternal smoking and asthma in adolescence

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Prenatal factors and the development of asthma

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Environmental exposure to endotoxin and its relation to asthma in school-age children

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The development of childhood asthma: lessons from the German Multicentre Allergy Study (MAS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

TLR4 gene variants modify endotoxin effects on asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Toll-like receptor 2 as a major gene for asthma in children of European farmers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Atopy and new-onset asthma in young Danish farmers and CD14, TLR2, and TLR4 genetic polymorphisms: a nested case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Toll-like receptor 4 polymorphism and severity of atopy in asthmatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Host-microbial interactions in childhood atopy: toll-like receptor 4 (TLR4), CD14, and fecal Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The role of lipopolysaccharide in the development of atopy in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Allergies, infections and the hygiene hypothesis--the epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Association of a promoter polymorphism of the CD14 gene and atopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Polymorphisms in the 5' region of the CD14 gene are associated with eczema in young children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Age-specific relationship between CD14 and atopy in a cohort assessed from age 8 to 25 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The potential of targeting Toll-like receptor 2 in autoimmune and inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Toll-like receptor heterodimer variants protect from childhood asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Bacterial infections and atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Bacterial DNA in house and farm barn dust

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Putative association of a TLR9 promoter polymorphism with atopic eczema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Transcriptional regulation of Tlr11 gene expression in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Association of toll-interacting protein gene polymorphisms with atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Opposite effects of CD 14/-260 on serum IgE levels in children raised in different environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Evaluation of the CD14 C-159 T polymorphism in the German Multicenter Allergy Study cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Learning from discrepancies: CD14 polymorphisms, atopy and the endotoxin switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Environmental epigenetics and allergic diseases: recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Epigenetic mechanisms and the relationship to childhood asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Polymorphisms in CD14, mannose-binding lectin, and Toll-like receptor-2 are associated with increased prevalence of infection in critically ill adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Innate immunity SNPs are associated with risk for severe sepsis after burn injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Association of polymorphisms of toll-like receptor 4 with a reduced prevalence of hay fever and atopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Genetics of allergic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Association between polymorphisms in caspase recruitment domain containing protein 15 and allergy in two German populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Polymorphisms in Toll-Like Receptor 4 Are Not Associated with Asthma or Atopy-related Phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case–control disease association studies☆☆This work was supported

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Common human Toll-like receptor 9 polymorphisms and haplotypes: association with atopy and functional relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

CD14and Toll-like Receptor Gene Polymorphisms, Country Living, and Asthma in Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Endotoxin Exposure, CD14, and Allergic Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Expression of CD14 and Toll-like receptor 2 in farmers' and nonfarmers' children

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1398-9995.2010.02489.X

10.1111/J.1398-9995.2010.02489.X

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

21039600