TRPM2 cation channels, oxidative stress and neurological diseases: where are we now? (Q37817844)

23 August 2017

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title

TRPM2 cation channels, oxidative stress and neurological diseases: where are we now? (English)

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23 August 2017

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Mustafa Nazıroğlu

1

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23 August 2017

8 December 2010

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23 August 2017

Neurochemical Research

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23 August 2017

36

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23 August 2017

3

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23 August 2017

355-366

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https://scigraph.springernature.com/pub.10.1007/s11064-010-0347-4

23 August 2017

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cites work

New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Oxidative stress and neurodegeneration: where are we now?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Effects of antioxidants on calcium influx through TRPM2 channels in transfected cells activated by hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Response to ADP-ribose by activation of TRPM2 in the CRI-G1 insulinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Flufenamic acid is a pH-dependent antagonist of TRPM2 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRP channels as cellular sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRP channel and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Transient receptor potential cation channels in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Transient receptor potential channels in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Second messenger function and the structure-activity relationship of cyclic adenosine diphosphoribose (cADPR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM channels, calcium and redox sensors during innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Intracellular calcium elevation induced by extracellular application of cyclic-ADP-ribose or oxytocin is temperature-sensitive in rodent NG108-15 neuronal cells with or without exogenous expression of human oxytocin receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Antagonist effect of flufenamic acid on TRPM2 cation channels activated by hydrogen peroxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Activation of T cell calcium influx by the second messenger ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM2 functions as a lysosomal Ca2+-release channel in beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM2 Ca2+ permeable cation channels: from gene to biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

The Ca2+ release-activated Ca2+ current (I(CRAC)) mediates store-operated Ca2+ entry in rat microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Multiple cascade effects of oxidative stress on astroglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

A critical role of TRPM2 in neuronal cell death by hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Nitric oxide activates TRP channels by cysteine S-nitrosylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

The pathogenesis of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Calcium and vitamin D metabolism in Guamanian Chamorros with amyotrophic lateral sclerosis and parkinsonism-dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Toxin-induced models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Glutamate-mediated influx of extracellular Ca2+ is coupled with reactive oxygen species generation in cultured hippocampal neurons but not in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Calmodulin signaling via the IQ motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Role of an N-terminal splice segment in the activation of the cation channel TRPM2 by ADP-ribose and hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Cell death in the injured brain: roles of metallothioneins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Transient receptor potential melastatin 2 expression is increased following experimental traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Role of selenium on calcium signaling and oxidative stress-induced molecular pathways in epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0347-4

Amyloid beta-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21140288

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TRP channels in disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21140288

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11064-010-0347-4

1 reference

23 August 2017

1 reference

PubMed ID

21140288