Role of cannabinoids in the treatment of pain and (painful) spasticity (Q37818137)

23 August 2017

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title

Role of cannabinoids in the treatment of pain and (painful) spasticity (English)

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23 August 2017

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Matthias Karst

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23 August 2017

Sonja Wippermann

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2

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23 August 2017

Jörg Ahrens

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3

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23 August 2017

language of work or name

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1 December 2010

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23 August 2017

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23 August 2017

70

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23 August 2017

18

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23 August 2017

2409-2438

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https://scigraph.springernature.com/pub.10.2165/11585260-000000000-00000

23 August 2017

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cites work

Cannabinoids: a new group of agonists of PPARs

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Effects of intravenous tetrahydrocannabinol on experimental and surgical pain. Psychological correlates of the analgesic response

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Cannabinoids in the management of difficult to treat pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

The analgesic properties of delta-9-tetrahydrocannabinol and codeine

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Analgesic Effect of Delta‐9‐Tetrahydrocannabinol

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Effect of benzopyranoperidine, a Δ-9-THC congener, on pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Effect of a nitrogen analog of tetrahydrocannabinol on cancer pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Safety, tolerability, and efficacy of orally administered cannabinoids in MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Adverse effects of medical cannabinoids: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11585260-000000000-00000

Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis

21 January 2018

1 reference

12 December 2020

Cannabinoid agonists attenuate capsaicin-induced responses in human skin

1 reference

12 December 2020

Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study

1 reference

12 December 2020

Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase

1 reference

12 December 2020

Cannabinoids. Structure-activity studies related to 1,2-dimethylheptyl derivatives.

1 reference

12 December 2020

Effects of marijuana smoking on pulmonary function and respiratory complications: a systematic review

1 reference

12 December 2020

Systematic review and meta-analysis of cannabis treatment for chronic pain

1 reference

12 December 2020

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

1 reference

12 December 2020

Inhibitors of monoacylglycerol lipase as novel analgesics

1 reference

12 December 2020

Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat.

1 reference

12 December 2020

Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

1 reference

12 December 2020

Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial

1 reference

12 December 2020

Pharmacology of cannabinoid CB1 and CB2 receptors.

1 reference

12 December 2020

Controlled-release oxycodone relieves neuropathic pain: a randomized controlled trial in painful diabetic neuropathy

1 reference

12 December 2020

Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model

1 reference

12 December 2020

Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients

1 reference

12 December 2020

Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice

1 reference

12 December 2020

The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial

1 reference

12 December 2020

Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain.

1 reference

12 December 2020

Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2Cannabinoid Receptors

1 reference

12 December 2020

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up.

1 reference

12 December 2020

Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation

1 reference

12 December 2020

Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : a double-blind placebo-controlled cross-over trial

1 reference

12 December 2020

PPAR-gamma: a nuclear receptor with affinity for cannabinoids

1 reference

12 December 2020

Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors.

1 reference

12 December 2020

Molecular characterization of a peripheral receptor for cannabinoids

1 reference

12 December 2020

Lack of analgesic efficacy of oral delta-9-tetrahydrocannabinol in postoperative pain

1 reference

12 December 2020

Delta(9)-tetrahydrocannabinol and the opioid receptor agonist piritramide do not act synergistically in postoperative pain

1 reference

12 December 2020

Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain

1 reference

12 December 2020

A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain

1 reference

12 December 2020

Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide].

1 reference

12 December 2020

Acidic Nonsteroidal Anti-inflammatory Drugs Inhibit Rat Brain Fatty Acid Amide Hydrolase in a pH-dependent Manner

1 reference

12 December 2020

The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain

1 reference

12 December 2020

Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis

1 reference

12 December 2020

The pharmacology of the cannabinoid system--a question of efficacy and selectivity

1 reference

12 December 2020

Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy

1 reference

12 December 2020

Randomized placebo-controlled double-blind clinical trial of cannabis-based medicinal product (Sativex) in painful diabetic neuropathy: depression is a major confounding factor

1 reference

12 December 2020

Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside

1 reference

12 December 2020

Cannabinoid CB2 receptor-mediated anti-nociception in models of acute and chronic pain

1 reference

12 December 2020

A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management

1 reference

12 December 2020

Actions of N-arachidonyl-glycine in a rat inflammatory pain model

1 reference

12 December 2020

Synergistic interactions between cannabinoid and opioid analgesics

1 reference

12 December 2020

Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain

1 reference

12 December 2020

Plant, synthetic, and endogenous cannabinoids in medicine

1 reference

12 December 2020

Cannabis and endocannabinoid modulators: Therapeutic promises and challenges

1 reference

12 December 2020

Lack of analgesia by oral standardized cannabis extract on acute inflammatory pain and hyperalgesia in volunteers.

1 reference

12 December 2020

Activational role of cannabinoids on movement

1 reference

12 December 2020

Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis

1 reference

12 December 2020

Analgesic and antihyperalgesic effects of nabilone on experimental heat pain

1 reference

12 December 2020

Cannabinoids in anaesthesia and pain therapy

1 reference

12 December 2020

Pre-emptive antinociceptive effects of a synthetic cannabinoid in a model of neuropathic pain

1 reference

12 December 2020

Nabilone in the treatment of multiple sclerosis.

1 reference

12 December 2020

Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial

1 reference

12 December 2020

Cannabinoid analgesia

1 reference

12 December 2020

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial

1 reference

12 December 2020

Therapeutic potential of cannabis in pain medicine

1 reference

12 December 2020

Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision

1 reference

12 December 2020

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

1 reference

12 December 2020

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833.

1 reference

12 December 2020

Open-label, add-on study of tetrahydrocannabinol for chronic nonmalignant pain

1 reference

12 December 2020

Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial

1 reference

12 December 2020

Endocannabinoid-mediated modulation of stress responses: physiological and pathophysiological significance

1 reference

12 December 2020

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

1 reference

12 December 2020

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1 reference

12 December 2020

Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study

1 reference

12 December 2020

Enhanced anandamide plasma levels in patients with complex regional pain syndrome following traumatic injury: a preliminary report

1 reference

12 December 2020

Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis

1 reference

12 December 2020

A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis.

1 reference

12 December 2020

Tetrahydrocannabinol (Delta 9-THC) Treatment in Chronic Central Neuropathic Pain and Fibromyalgia Patients: Results of a Multicenter Survey

1 reference

12 December 2020

The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain

1 reference

12 December 2020

Cannabinoids against pain. Efficacy and strategies to reduce psychoactivity: a clinical perspective

1 reference

12 December 2020

Effects of nabilone, a synthetic cannabinoid, on postoperative pain.

1 reference

12 December 2020

Agonistic properties of cannabidiol at 5-HT1a receptors

1 reference

12 December 2020

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

1 reference

12 December 2020

Sativex successfully treats neuropathic pain characterised by allodynia: a randomised, double-blind, placebo-controlled clinical trial

1 reference

12 December 2020

Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain.

1 reference

12 December 2020

A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833

1 reference

12 December 2020

Endogenous cannabinoid as a retrograde messenger from depolarized postsynaptic neurons to presynaptic terminals

1 reference

12 December 2020

Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine

1 reference

12 December 2020

Aspirin and acetaminophen reduced both Fos expression in rat lumbar spinal cord and inflammatory signs produced by carrageenin inflammation

1 reference

12 December 2020

Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis

1 reference

12 December 2020

Are oral cannabinoids safe and effective in refractory neuropathic pain?

1 reference

12 December 2020

Activation of peripheral cannabinoid CB1 and CB2 receptors suppresses the maintenance of inflammatory nociception: a comparative analysis

1 reference

12 December 2020

Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief

1 reference

12 December 2020

Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw.

1 reference

12 December 2020

The endocannabinoid system: current pharmacological research and therapeutic possibilities

1 reference

12 December 2020

A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms

1 reference

12 December 2020

Neuropathic pain: emerging treatments

1 reference

12 December 2020

Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 'N of 1' studies

1 reference

12 December 2020

Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat.

1 reference

12 December 2020

Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved

1 reference

12 December 2020

Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain

1 reference

12 December 2020

Inhibitory and stimulatory effects of cannabinoids on eicosanoid synthesis.

1 reference

12 December 2020

[Benefits of an add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain--a randomized controlled trial]

1 reference

12 December 2020

Nabilone for the treatment of pain in fibromyalgia

1 reference

12 December 2020

Pain measurements and side effect profile of the novel cannabinoid ajulemic acid

1 reference

12 December 2020

Pain relief with oral cannabinoids in familial Mediterranean fever

1 reference

12 December 2020

Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats

1 reference

12 December 2020

AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain

1 reference

12 December 2020

High-potency cannabis and the risk of psychosis

1 reference

12 December 2020

Endocannabinoid mechanisms of pain modulation

1 reference

12 December 2020

Opioids for neuropathic pain

1 reference

12 December 2020

Analgesic and antiinflammatory effects of cannabinoid receptor agonists in a rat model of neuropathic pain

1 reference

12 December 2020

Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration

1 reference

12 December 2020

Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study

1 reference

12 December 2020

Effect of the cannabinoid ajulemic acid on rat models of neuropathic and inflammatory pain

1 reference

12 December 2020

Topical cannabinoid enhances topical morphine antinociception.

1 reference

12 December 2020

Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

1 reference

12 December 2020

[The endogenous cannabinoid system. Therapeutic implications for neurologic and psychiatric disorders].

1 reference

12 December 2020

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis

1 reference

12 December 2020

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis.

1 reference

12 December 2020

Assessing the quality of reports of randomized clinical trials: is blinding necessary?

1 reference

12 December 2020

Antinociceptive, subjective and behavioral effects of smoked marijuana in humans.

1 reference

12 December 2020

Reassessment of the role of cannabinoids in the management of pain

1 reference

12 December 2020

The treatment of spasticity with Delta9-tetrahydrocannabinol in persons with spinal cord injury.

1 reference

12 December 2020

Cannabis; adverse effects from an oromucosal spray

1 reference

12 December 2020

Biphasic effects of anandamide

1 reference

12 December 2020

Evaluation of intramuscular levonantradol and placebo in acute postoperative pain

1 reference

12 December 2020

CB2 cannabinoid receptor mediation of antinociception.

1 reference

12 December 2020

Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation

1 reference

12 December 2020

Cannabinoids in multiple sclerosis: do they have a therapeutic role?

1 reference

12 December 2020

Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat

1 reference

12 December 2020

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1 reference

12 December 2020

Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats

1 reference

12 December 2020

Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers.

1 reference

12 December 2020

Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain

1 reference

12 December 2020

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

1 reference

12 December 2020

Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation

1 reference

12 December 2020

Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig

1 reference

12 December 2020

Cannabinoids in medicine: A review of their therapeutic potential

1 reference

12 December 2020

The future of cannabinoids as analgesic agents: a pharmacologic, pharmacokinetic, and pharmacodynamic overview

1 reference

12 December 2020

An endocannabinoid mechanism for stress-induced analgesia.

1 reference

12 December 2020

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS

1 reference

12 December 2020

Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs

1 reference

12 December 2020

The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions

1 reference

12 December 2020

Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy

1 reference

12 December 2020

Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial

1 reference

12 December 2020

Analgesic effects of 1',1' dimethylheptyl-delta8-THC-11-oic acid (CT3) in mice

1 reference

12 December 2020

Treatment of Human Spasticity with Δ9-Tetrahydrocannabinol

1 reference

12 December 2020

Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review

1 reference

12 December 2020

Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale

1 reference

12 December 2020

Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial

1 reference

12 December 2020

Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization.

1 reference

12 December 2020

Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial

1 reference

12 December 2020

Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat.

1 reference

12 December 2020

Selective Activation of Cannabinoid CB2 Receptors Suppresses Hyperalgesia Evoked by Intradermal Capsaicin

1 reference

12 December 2020

Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.

1 reference

12 December 2020

Efficacy of opioids for chronic pain: a review of the evidence

1 reference

12 December 2020

Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat.

1 reference

12 December 2020

Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain

1 reference

12 December 2020

A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury.

1 reference

12 December 2020

10.2165/11585260-000000000-00000

Identifiers

DOI

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Dimensions Publication ID

23 August 2017

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