Antiviral responses induced by the TLR3 pathway (Q37839894)

24 August 2017

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title

Antiviral responses induced by the TLR3 pathway (English)

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24 August 2017

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Misako Matsumoto

1

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PubMed ID

21312311

24 August 2017

Hiroyuki Oshiumi

series ordinal

2

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PubMed ID

21312311

24 August 2017

Tsukasa Seya

series ordinal

3

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24 August 2017

10 February 2011

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Reviews in Medical Virology

24 August 2017

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24 August 2017

21

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24 August 2017

67-77

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24 August 2017

2

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Functional role of type I and type II interferons in antiviral defense

24 August 2017

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Fifty years of interferon research: aiming at a moving target

21 January 2018

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Type 1 interferons and the virus-host relationship: a lesson in détente .

21 January 2018

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PKR--a protein kinase regulated by double-stranded RNA.

21 January 2018

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Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

21 January 2018

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

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Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

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Pathogen recognition and innate immunity

21 January 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

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Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling

21 January 2018

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TLR3: interferon induction by double-stranded RNA including poly(I:C).

21 January 2018

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Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

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Autophagy-dependent viral recognition by plasmacytoid dendritic cells

21 January 2018

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5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

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Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

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5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

21 January 2018

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RIG-I detects viral genomic RNA during negative-strand RNA virus infection

21 January 2018

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

21 January 2018

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Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

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Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

21 January 2018

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

21 January 2018

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A family of human receptors structurally related to Drosophila Toll

21 January 2018

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Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon

21 January 2018

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Preferential expression and function of Toll-like receptor 3 in human astrocytes

21 January 2018

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Microglia recognize double-stranded RNA via TLR3.

21 January 2018

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Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

21 January 2018

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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

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Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 January 2018

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Subcellular localization of Toll-like receptor 3 in human dendritic cells

21 January 2018

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Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

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TLR3-mediated synthesis and release of eotaxin-1/CCL11 from human bronchial smooth muscle cells stimulated with double-stranded RNA.

21 January 2018

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Increased expression of Toll-like receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers

21 January 2018

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Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA.

21 January 2018

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The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signaling

21 January 2018

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TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements

21 January 2018

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IFNs activate toll-like receptor gene expression in viral infections

21 January 2018

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Species-specific regulation of Toll-like receptor 3 genes in men and mice.

21 January 2018

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Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains.

21 January 2018

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Toll-like receptors as molecular switches.

21 January 2018

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Leucine-rich repeats and pathogen recognition in Toll-like receptors.

21 January 2018

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Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

21 January 2018

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The molecular structure of the Toll-like receptor 3 ligand-binding domain.

21 January 2018

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The dsRNA binding site of human Toll-like receptor 3.

21 January 2018

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Modulation of double-stranded RNA recognition by the N-terminal histidine-rich region of the human toll-like receptor 3.

21 January 2018

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The TLR3 signaling complex forms by cooperative receptor dimerization

21 January 2018

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

21 January 2018

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Illuminating the silence: understanding the structure and function of small RNAs

21 January 2018

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

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Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling

21 January 2018

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Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

21 January 2018

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TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

21 January 2018

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

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Homo-oligomerization is essential for Toll/interleukin-1 receptor domain-containing adaptor molecule-1-mediated NF-kappaB and interferon regulatory factor-3 activation

21 January 2018

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Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

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Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

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Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway

21 January 2018

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Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

21 January 2018

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

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Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation

21 January 2018

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A molecular mechanism for Toll-IL-1 receptor domain-containing adaptor molecule-1-mediated IRF-3 activation

21 January 2018

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RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

21 January 2018

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Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

21 January 2018

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Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

21 January 2018

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Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling

21 January 2018

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The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

21 January 2018

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DUBA: a deubiquitinase that regulates type I interferon production

21 January 2018

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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Does Toll-like receptor 3 play a biological role in virus infections?

21 January 2018

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Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury

21 January 2018

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A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

21 January 2018

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Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

21 January 2018

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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection

21 January 2018

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Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus

21 January 2018

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Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression.

21 January 2018

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Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection

21 January 2018

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Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia

21 January 2018

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TLR3 deletion limits mortality and disease severity due to Phlebovirus infection.

21 January 2018

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Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

21 January 2018

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Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

21 January 2018

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Priming of T cells by exogenous antigen cross-presented on MHC class I molecules

21 January 2018

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Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

21 January 2018

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Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

21 January 2018

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Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells

21 January 2018

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Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

21 January 2018

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The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells

21 January 2018

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Toll-like receptor 3 promotes cross-priming to virus-infected cells.

21 January 2018

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Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

21 January 2018

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Hepatitis C virus-infected hepatocytes extrinsically modulate dendritic cell maturation to activate T cells and natural killer cells

21 January 2018

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TLR3 deficiency in patients with herpes simplex encephalitis

21 January 2018

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Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.

21 January 2018

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Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells

21 January 2018

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Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation

21 January 2018

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Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

21 January 2018

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Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells

21 January 2018

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Double-stranded RNA-mediated TLR3 activation is enhanced by CD14.

21 January 2018

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The clathrin-mediated endocytic pathway participates in dsRNA-induced IFN-beta production

21 January 2018

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Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure

21 January 2018

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TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/RMV.680

1 reference

24 August 2017

1 reference

PubMed ID

21312311