HFE gene variants affect iron in the brain (Q37846398)

24 August 2017

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title

HFE gene variants affect iron in the brain (English)

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24 August 2017

Wint Nandar

1

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24 August 2017

James R Connor

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

23 February 2011

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24 August 2017

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24 August 2017

141

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24 August 2017

4

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24 August 2017

729S-739S

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Iron in neuronal function and dysfunction

24 August 2017

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Reactive oxygen species and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron and ageing: an introduction to iron regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron, brain ageing and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Brain iron homeostasis and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The effect of age on the non-haemin iron in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Normal deposition of brain iron in childhood and adolescence: MR imaging at 1.5 T.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Chronic cerebellar ataxia and hereditary hemochromatosis: causal or coincidental association?

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Global prevalence of putative haemochromatosis mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Genetic mechanisms and modifying factors in hereditary hemochromatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron-overload-related disease in HFE hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Geography of HFE C282Y and H63D mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Structure, function, and diversity of class I major histocompatibility complex molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Intracellular transport blockade caused by disruption of the disulfide bridge in the third external domain of major histocompatibility complex class I antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The role of iron neurotoxicity in ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Kupffer cell staining by an HFE-specific monoclonal antibody: implications for hereditary haemochromatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Clinical and biochemical abnormalities in people heterozygous for hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The significance of haemochromatosis gene mutations in the general population: implications for screening

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Plasma biomarkers associated with ALS and their relationship to iron homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Nutritional assessment and survival in ALS patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Amyotrophic lateral sclerosis, enteral nutrition and the risk of iron overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Minocycline delays disease onset and mortality in a transgenic model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Early AGEing and Alzheimer's.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

A tombstone in Alzheimer's?

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The transition metals copper and iron in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Redox-active iron mediates amyloid-beta toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Regulation of Hfe by stress factors in BV-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The hemochromatosis gene affects the age of onset of sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

CAT53 and HFE alleles in Alzheimer's disease: a putative protective role of the C282Y HFE mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Transferrin C2 allele, haemochromatosis gene mutations, and risk for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Evaluation of HFE (hemochromatosis) mutations as genetic modifiers in sporadic AD and MCI.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron, the substantia nigra and related neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Concurrent hereditary haemochromatosis and idiopathic Parkinson's disease: a case report series

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Screening for mutations of the HFE gene in Parkinson's disease patients with hyperechogenicity of the substantia nigra

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Genetic predisposition to Parkinson's disease: CYP2D6 and HFE in the Faroe Islands.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

HFE gene mutations in a population of Italian Parkinson's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Adult nutrient intake as a risk factor for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron accumulation in the basal ganglia following severe ischemic-anoxic insults in children

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Serum ferritin is a risk factor for stroke in postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Increased body iron stores are associated with poor outcome after thrombolytic treatment in acute stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Mutations in the hemochromatosis gene (HFE) and stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Hereditary hemochromatosis genotypes and risk of ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Iron Stores and HFE Genotypes Are Not Related to Increased Risk of Ischemic Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Modifying factors of the HFE hemochromatosis phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Identification of a mouse homolog for the human hereditary haemochromatosis candidate gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

HFE gene knockout produces mouse model of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Movement disorders in the Hfe knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

HFE variants, APOE and Alzheimer's disease: Findings from the population-based Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

The Association Between H63D Mutations in HFE and Amyotrophic Lateral Sclerosis in a Dutch Population

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3945%2FJN.110.130351

21 January 2018

Identifiers

DOI

10.3945/JN.110.130351

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release_zlp5ligtwndubfxvhm5svunovq

24 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/zlp5ligtwndubfxvhm5svunovq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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