Post-proteasomal and proteasome-independent generation of MHC class I ligands. (Q37851391)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21390545%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

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title

Post-proteasomal and proteasome-independent generation of MHC class I ligands (English)

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25 January 2020

1

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25 January 2020

author name string

Peter van Endert

series ordinal

1

1 reference

24 August 2017

publication date

10 March 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21390545%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

25 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21390545%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

68

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issue

9

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25 January 2020

page(s)

1553-1567

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https://scigraph.springernature.com/pub.10.1007/s00018-011-0662-1

25 January 2020

exact match

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A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation.

21 January 2018

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Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation

21 January 2018

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No essential role for tripeptidyl peptidase II for the processing of LCMV-derived T cell epitopes

21 January 2018

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Tripeptidyl peptidase II is dispensable for the generation of both proteasome-dependent and proteasome-independent ligands of HLA-B27 and other class I molecules

21 January 2018

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Need for tripeptidyl-peptidase II in major histocompatibility complex class I viral antigen processing when proteasomes are detrimental

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Re-evaluating the generation of a "proteasome-independent" MHC class I-restricted CD8 T cell epitope

21 January 2018

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Processing of two latent membrane protein 1 MHC class I epitopes requires tripeptidyl peptidase II involvement.

21 January 2018

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ISCOMATRIX adjuvant induces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via tripeptidyl peptidase II.

21 January 2018

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Caspases in virus-infected cells contribute to recognition by CD8+ T lymphocytes

21 January 2018

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Production of an antigenic peptide by insulin-degrading enzyme

21 January 2018

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Insulin degradation: progress and potential

21 January 2018

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Insulin-degrading enzyme: embarking on amyloid destruction.

21 January 2018

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Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases

21 January 2018

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21 January 2018

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Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation

21 January 2018

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Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.

21 January 2018

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Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

21 January 2018

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ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 January 2018

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Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

21 January 2018

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The oxytocinase subfamily of M1 aminopeptidases

21 January 2018

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IRAP identifies an endosomal compartment required for MHC class I cross-presentation

21 January 2018

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Proteasome activator and antigen-processing aminopeptidases are regulated by virus-induced type I interferon in the hepatitis C virus-infected liver

21 January 2018

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Regulation of the human leukocyte-derived arginine aminopeptidase/endoplasmic reticulum-aminopeptidase 2 gene by interferon-gamma

21 January 2018

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NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells

21 January 2018

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Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding

21 January 2018

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Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

An Aminopeptidase, ARTS-1, Is Required for Interleukin-6 Receptor Shedding

21 January 2018

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Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.

21 January 2018

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Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues

21 January 2018

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Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation

21 January 2018

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Endoplasmic reticulum aminopeptidase-1 mediates leukemia inhibitory factor-induced cell surface human leukocyte antigen-G expression in JEG-3 choriocarcinoma cells

21 January 2018

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The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism.

21 January 2018

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The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 January 2018

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Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1

21 January 2018

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The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.

21 January 2018

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The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum.

21 January 2018

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Glutamine-181 is crucial in the enzymatic activity and substrate specificity of human endoplasmic-reticulum aminopeptidase-1.

21 January 2018

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Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases

21 January 2018

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Cellular peptide composition governed by major histocompatibility complex class I molecules.

21 January 2018

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ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum

21 January 2018

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Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum

21 January 2018

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H-2Ld class I molecule protects an HIV N-extended epitope from in vitro trimming by endoplasmic reticulum aminopeptidase associated with antigen processing

21 January 2018

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The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

21 January 2018

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A detailed analysis of the murine TAP transporter substrate specificity

21 January 2018

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Cross-talk between the endocytic pathway and the endoplasmic reticulum in cross-presentation by MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma

21 January 2018

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Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Investigating the genetic association between ERAP1 and ankylosing spondylitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

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Characterizing the N-terminal processing motif of MHC class I ligands

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Characterizing the specificity and cooperation of aminopeptidases in the cytosol and endoplasmic reticulum during MHC class I antigen presentation

21 January 2018

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Trafficking of spontaneously endocytosed MHC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Recycling MHC class I molecules and endosomal peptide loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Defective cross-presentation of viral antigens in GILT-free mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Insulin-regulated aminopeptidase marks an antigen-stimulated recycling compartment in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

A proteolytic system that compensates for loss of proteasome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0662-1

Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses

21 January 2018

1 reference

12 December 2020

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1

1 reference

12 December 2020

Genetic variation of antigen processing machinery components and association with cervical carcinoma

1 reference

12 December 2020

The Enigma of Tripeptidyl-Peptidase II: Dual Roles in Housekeeping and Stress.

1 reference

12 December 2020

Allelic differences in the relationship between proteasome activity and MHC class I peptide loading.

1 reference

12 December 2020

Generation of MHC class I ligands in the secretory and vesicular pathways

1 reference

12 December 2020

The insulin-regulated aminopeptidase: a companion and regulator of GLUT4

1 reference

12 December 2020

The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation

1 reference

12 December 2020

The role of the proteasome in the generation of MHC class I ligands and immune responses

1 reference

12 December 2020

Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival

1 reference

12 December 2020

10.1007/S00018-011-0662-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21390545%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference