HIV sexual transmission and microbicides (Q37853935)

24 August 2017

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HIV sexual transmission and microbicides (English)

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sexually transmitted infection

24 August 2017

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2

Vicky Jespers

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24 August 2017

1

Kevin K Ariën

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24 August 2017

Guido Vanham

3

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24 August 2017

15 March 2011

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Reviews in Medical Virology

24 August 2017

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24 August 2017

21

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24 August 2017

2

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24 August 2017

110-133

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The role of sexually transmitted diseases in HIV transmission

24 August 2017

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Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda

21 January 2018

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Circumcision and HIV transmission

21 January 2018

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Rethinking the heterosexual infectivity of HIV-1: a systematic review and meta-analysis

21 January 2018

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Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

21 January 2018

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Inhibiting sexual transmission of HIV-1 infection

21 January 2018

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Preexposure chemoprophylaxis for HIV prevention in men who have sex with men

21 January 2018

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Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN.

21 January 2018

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Semen-derived amyloid fibrils drastically enhance HIV infection

21 January 2018

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Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI.

21 January 2018

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Enhanced cellular responses and environmental sampling within inner foreskin explants: implications for the foreskin's role in HIV transmission

21 January 2018

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Abundant expression of HIV target cells and C-type lectin receptors in the foreskin tissue of young Kenyan men.

21 January 2018

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Expression of DC-SIGN in human foreskin may facilitate sexual transmission of HIV.

21 January 2018

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HIV-1 infection of human penile explant tissue and protection by candidate microbicides

21 January 2018

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Potential HIV-1 target cells in the human penis

21 January 2018

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Detection of HIV-1 in seminal plasma and seminal cells of HIV-1 seropositive men.

21 January 2018

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Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells

21 January 2018

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Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles

21 January 2018

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Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses

21 January 2018

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Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus

21 January 2018

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The innate and early immune response to pathogen challenge in the female genital tract and the pivotal role of epithelial cells

21 January 2018

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Effect of treatment of asymptomatic bacterial vaginosis on HIV-1 shedding in the genital tract among women on antiretroviral therapy: a pilot study

21 January 2018

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Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus

21 January 2018

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Recent observations on HIV type-1 infection in the genital tract of men and women

21 January 2018

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Bacterial vaginosis and HIV acquisition: a meta-analysis of published studies

21 January 2018

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Leukocytes migrate through three-dimensional gels of midcycle cervical mucus

21 January 2018

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Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model.

21 January 2018

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Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa

21 January 2018

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Memory CD4(+) T cells are the earliest detectable human immunodeficiency virus type 1 (HIV-1)-infected cells in the female genital mucosal tissue during HIV-1 transmission in an organ culture system

21 January 2018

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Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection

21 January 2018

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HIV type 1 infection in women: increased transcription of HIV type 1 in ectocervical tissue explants.

21 January 2018

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DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

21 January 2018

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Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques

21 January 2018

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Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

21 January 2018

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Young age is a risk factor for HIV among female sex workers--an experience from India.

21 January 2018

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Cervical ectopy in adolescent girls with and without human immunodeficiency virus infection

21 January 2018

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Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

21 January 2018

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Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial

21 January 2018

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Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial

21 January 2018

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Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial

21 January 2018

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Topical oestrogen keratinises the human foreskin and may help prevent HIV infection

21 January 2018

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Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group

21 January 2018

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Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa.

21 January 2018

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Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels

21 January 2018

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Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection

21 January 2018

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Selection of HIV variants with signature genotypic characteristics during heterosexual transmission

21 January 2018

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Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity

21 January 2018

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Virus population homogenization following acute human immunodeficiency virus type 1 infection

21 January 2018

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Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing

21 January 2018

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Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

21 January 2018

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Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

21 January 2018

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Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants

21 January 2018

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Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1

21 January 2018

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HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort study

21 January 2018

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HIV-1 genomic RNA diversification following sexual and parenteral virus transmission

21 January 2018

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Genotypic and phenotypic characterization of HIV-1 patients with primary infection

21 January 2018

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Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission.

21 January 2018

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Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission

21 January 2018

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Viral characteristics of transmitted HIV.

21 January 2018

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Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

21 January 2018

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Gender differences in HIV-1 diversity at time of infection

21 January 2018

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HIV type 1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus

21 January 2018

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Multiple V1/V2 env variants are frequently present during primary infection with human immunodeficiency virus type 1

21 January 2018

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Human immunodeficiency virus type 1 (HIV-1) diversity at time of infection is not restricted to certain risk groups or specific HIV-1 subtypes

21 January 2018

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Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda

21 January 2018

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Sexual transmission of HIV: infectiousness and prevention

21 January 2018

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

21 January 2018

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

21 January 2018

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High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.

21 January 2018

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Wide variation in the multiplicity of HIV-1 infection among injection drug users

21 January 2018

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Sexual risk behaviour for transmission of HIV in men who have sex with men: recent findings and potential interventions

21 January 2018

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Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.

21 January 2018

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Historical perspective on HIV‐exposed seronegative individuals: has nature done the experiment for us?

21 January 2018

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Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

21 January 2018

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

21 January 2018

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Global distribution of the CCR5 gene 32-basepair deletion.

21 January 2018

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Anti-retroviral activity of TRIM5 alpha

21 January 2018

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Determinants of protection among HIV‐exposed seronegative persons: an overview

21 January 2018

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Elucidating the elite: mechanisms of control in HIV-1 infection

21 January 2018

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Human immunodeficiency virus (HIV)-specific cytotoxic T lymphocyte activity in HIV-exposed seronegative persons

21 January 2018

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Protection against human immunodeficiency virus type 1 infection in persons with repeated exposure: evidence for T cell immunity in the absence of inherited CCR5 coreceptor defects

21 January 2018

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HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers

21 January 2018

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Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomised controlled trial

21 January 2018

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Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial

21 January 2018

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A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases

21 January 2018

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Phase 1 trial of nonoxynol-9 film among sex workers in South Africa

21 January 2018

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Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

21 January 2018

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Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity

21 January 2018

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Inactivation of human immunodeficiency virus type 1 by nonoxynol-9, C31G, or an alkyl sulfate, sodium dodecyl sulfate

21 January 2018

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Microbicides--evaluating multiple formulations of C31G.

21 January 2018

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Safety of single daily use for one week of C31G HEC gel in women.

21 January 2018

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SAVVY vaginal gel (C31G) for prevention of HIV infection: a randomized controlled trial in Nigeria

21 January 2018

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Sodium lauryl sulfate, a microbicide effective against enveloped and nonenveloped viruses

21 January 2018

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Thermoreversible Gel Formulation Containing Sodium Lauryl Sulfate as a Potential Contraceptive Device

21 January 2018

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Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases

21 January 2018

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A randomized, double-blind, placebo-controlled safety and acceptability study of two Invisible Condom formulations in women from Cameroon

21 January 2018

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A randomized, double-blind, placebo-controlled Phase II extended safety study of two Invisible Condom formulations in Cameroonian women

21 January 2018

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Acid sensitivity of cell-free and cell-associated HIV-1: clinical implications

21 January 2018

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Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.

21 January 2018

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Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States

21 January 2018

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Safety and acceptability of penile application of 2 candidate topical microbicides: BufferGel and PRO 2000 Gel: 3 randomized trials in healthy low-risk men and HIV-positive men.

21 January 2018

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Male tolerance of ACIDFORM gel.

21 January 2018

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ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations

21 January 2018

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Phase I safety trial of two vaginal microbicide gels (Acidform or BufferGel) used with a diaphragm compared to KY jelly used with a diaphragm

21 January 2018

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Vaginal microbicide and diaphragm use for sexually transmitted infection prevention: a randomized acceptability and feasibility study among high-risk women in Madagascar

21 January 2018

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Results of a safety and feasibility study of the diaphragm used with ACIDFORM Gel or K-Y Jelly

21 January 2018

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DNA Fingerprinting of Lactobacillus crispatus Strain CTV-05 by Repetitive Element Sequence-Based PCR Analysis in a Pilot Study of Vaginal Colonization

21 January 2018

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Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4

21 January 2018

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Toward a live microbial microbicide for HIV: commensal bacteria secreting an HIV fusion inhibitor peptide

21 January 2018

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Activity of HIV entry and fusion inhibitors expressed by the human vaginal colonizing probiotic Lactobacillus reuteri RC-14.

21 January 2018

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The antiviral protein cyanovirin-N: the current state of its production and applications

21 January 2018

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Lime juice as a candidate microbicide? An open-label safety trial of 10% and 20% lime juice used vaginally

21 January 2018

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Prevalence of HIV and other sexually transmissible infections in relation to lemon or lime juice douching among female sex workers in Jos, Nigeria.

21 January 2018

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Six-day randomized safety trial of intravaginal lime juice

21 January 2018

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Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells

21 January 2018

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Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120

21 January 2018

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PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial

21 January 2018

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A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women

21 January 2018

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Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women.

21 January 2018

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PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial

21 January 2018

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Preliminary safety and acceptability of a carrageenan gel for possible use as a vaginal microbicide

21 January 2018

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No increase in cervicovaginal proinflammatory cytokines after Carraguard use in a placebo-controlled randomized clinical trial.

21 January 2018

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Carraguard Vaginal Gel Safety in HIV-Positive Women and Men in South Africa

21 January 2018

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Safety and acceptability of the candidate microbicide Carraguard in Thai Women: findings from a Phase II Clinical Trial

21 January 2018

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Microbicide trials for preventing HIV/AIDS in South Africa: phase II trial partricipants' experiences and psychological needs.

21 January 2018

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Two novel vaginal microbicides (polystyrene sulfonate and cellulose sulfate) inhibit Gardnerella vaginalis and anaerobes commonly associated with bacterial vaginosis

21 January 2018

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Papillomavirus microbicidal activities of high-molecular-weight cellulose sulfate, dextran sulfate, and polystyrene sulfonate

21 January 2018

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Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action.

21 January 2018

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Single and multiple exposure tolerance study of cellulose sulfate gel: a Phase I safety and colposcopy study.

21 January 2018

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Cellulose sulfate: tolerance and acceptability of penile application

21 January 2018

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Safety and acceptability of cellulose sulfate as a vaginal microbicide in HIV-infected women.

21 January 2018

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Fourteen-day safety and acceptability study of 6% cellulose sulfate gel: a randomized double-blind Phase I safety study

21 January 2018

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Expanded Phase I safety and acceptability study of 6% cellulose sulfate vaginal gel.

21 January 2018

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Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission

21 January 2018

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Effectiveness of cellulose sulfate vaginal gel for the prevention of HIV infection: results of a Phase III trial in Nigeria

21 January 2018

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Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120

21 January 2018

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Cellulose acetate 1,2-benzenedicarboxylate inhibits infection by cell-free and cell-associated primary HIV-1 isolates

21 January 2018

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Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles

21 January 2018

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Cellulose acetate 1,2-benzenedicarboxylate protects against challenge with pathogenic X4 and R5 simian/human immunodeficiency virus

21 January 2018

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Multiple vaginal exposures to low doses of R5 simian-human immunodeficiency virus: strategy to study HIV preclinical interventions in nonhuman primates

21 January 2018

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Safety and distribution of cellulose acetate 1,2-benzenedicarboxylate (CAP), a candidate anti-HIV microbicide in rhesus macaques

21 January 2018

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Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection

21 January 2018

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Structure activity relationship of dendrimer microbicides with dual action antiviral activity

21 January 2018

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Identification of a dendrimeric heparan sulfate-binding peptide that inhibits infectivity of genital types of human papillomaviruses.

21 January 2018

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"Viologen" dendrimers as antiviral agents: the effect of charge number and distance

21 January 2018

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Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.

21 January 2018

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Glycerol monolaurate prevents mucosal SIV transmission

21 January 2018

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Targeting early infection to prevent HIV-1 mucosal transmission.

21 January 2018

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Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs

21 January 2018

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PSC-RANTES blocks R5 human immunodeficiency virus infection of Langerhans cells isolated from individuals with a variety of CCR5 diplotypes

21 January 2018

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R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms

21 January 2018

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Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

21 January 2018

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Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide

21 January 2018

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Chemokine analogues show suitable stability for development as microbicides.

21 January 2018

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Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge

21 January 2018

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Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor

21 January 2018

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Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

21 January 2018

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Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes

21 January 2018

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CD4 mimetic miniproteins: potent anti-HIV compounds with promising activity as microbicides

21 January 2018

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The role of antibodies in HIV vaccines

21 January 2018

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A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

21 January 2018

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

21 January 2018

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

21 January 2018

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Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

21 January 2018

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Naturally occurring antibodies devoid of light chains

21 January 2018

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Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120

21 January 2018

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Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

21 January 2018

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Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

21 January 2018

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Isolation of antigen specific llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae

21 January 2018

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Single-domain antibody fragments with high conformational stability

21 January 2018

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Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies

21 January 2018

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Efficient cancer therapy with a nanobody-based conjugate

21 January 2018

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Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis.

21 January 2018

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Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo

21 January 2018

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A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme

21 January 2018

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Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies

21 January 2018

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Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice

21 January 2018

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Generation of a family-specific phage library of llama single chain antibody fragments that neutralize HIV-1

21 January 2018

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Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction

21 January 2018

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Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody

21 January 2018

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Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

21 January 2018

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Carbohydrate-binding agents: a potential future cornerstone for the chemotherapy of enveloped viruses?

21 January 2018

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Exploiting the defensive sugars of HIV-1 for drug and vaccine design

21 January 2018

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

21 January 2018

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Cyanovirin-N potently inhibits human immunodeficiency virus type 1 infection in cellular and cervical explant models

21 January 2018

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Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 January 2018

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Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.

21 January 2018

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Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120.

21 January 2018

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Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope

21 January 2018

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Mechanism by which the lectin actinohivin blocks HIV infection of target cells

21 January 2018

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Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp

21 January 2018

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Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide

21 January 2018

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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

21 January 2018

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Potent anti-HIV activity of scytovirin domain 1 peptide.

21 January 2018

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Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

21 January 2018

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Microvirin, a novel alpha(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of cyanovirin-N but a much higher safety profile

21 January 2018

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New insights on interactions between HIV-1 and HSV-2.

21 January 2018

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Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: a meta-analysis

21 January 2018

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Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies.

21 January 2018

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Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults

21 January 2018

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Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

21 January 2018

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Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

21 January 2018

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In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides

21 January 2018

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Preclinical studies on thiocarboxanilide UC-781 as a virucidal agent.

21 January 2018

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In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1

21 January 2018

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In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides

21 January 2018

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A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides

21 January 2018

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Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781.

21 January 2018

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The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells

21 January 2018

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Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor

21 January 2018

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In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection

21 January 2018

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Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection

21 January 2018

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Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women

21 January 2018

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Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings.

21 January 2018

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Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir

21 January 2018

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Dose-ranging phase 1 study of TMC120, a promising vaginal microbicide, in HIV-negative and HIV-positive female volunteers

21 January 2018

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Inhibition of HIV-1 by non-nucleoside reverse transcriptase inhibitors via an induced fit mechanism-Importance of slow dissociation and relaxation rates for antiviral efficacy

21 January 2018

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A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy

21 January 2018

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An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques

21 January 2018

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Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

21 January 2018

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Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor

21 January 2018

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Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model

21 January 2018

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Evaluation of antiretrovirals in animal models of HIV infection.

21 January 2018

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Infection of macaques after vaginal exposure to cell-associated simian immunodeficiency virus

21 January 2018

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Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009).

21 January 2018

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Microbicides and other topical strategies to prevent vaginal transmission of HIV.

21 January 2018

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Is HIV drug resistance a limiting factor in the development of anti-HIV NNRTI and NRTI-based vaginal microbicide strategies?

21 January 2018

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Drug-susceptible HIV-1 infection despite intermittent fixed-dose combination tenofovir/emtricitabine as prophylaxis is associated with low-level viremia, delayed seroconversion, and an attenuated clinical course

21 January 2018

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Transmission of drug-resistant HIV-1 is stabilizing in Europe

21 January 2018

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The risk of HIV drug resistance following implementation of pre-exposure prophylaxis

21 January 2018

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Human immunodeficiency virus type 1 resistance or cross-resistance to nonnucleoside reverse transcriptase inhibitors currently under development as microbicides

21 January 2018

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Incidence of HIV‐1 Dual Infection and Its Association with Increased Viral Load Set Point in a Cohort of HIV‐1 Subtype C–Infected Female Sex Workers

21 January 2018

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Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor

21 January 2018

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Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring

21 January 2018

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The Efficiency of Male-to Female and Female-to-Male Sexual Transmission of the Human Immunodeficiency Virus

21 January 2018

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P07-06. HIV-1 transmission and early evolution: whole genome analysis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/RMV.684

1 reference

24 August 2017

1 reference

PubMed ID

21412935