Protein kinase Cε as a cancer marker and target for anticancer therapy (Q37858343)

24 August 2017

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title

Protein kinase Cε as a cancer marker and target for anticancer therapy (English)

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24 August 2017

Ewa Totoń

1

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24 August 2017

Ewa Ignatowicz

series ordinal

2

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24 August 2017

Karolina Skrzeczkowska

series ordinal

3

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24 August 2017

Maria Rybczyńska

series ordinal

4

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24 August 2017

1 January 2011

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24 August 2017

Pharmacological Reports

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24 August 2017

63

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24 August 2017

1

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24 August 2017

19-29

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Protein kinase C epsilon: a new target to control inflammation and immune-mediated disorders

24 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein Kinase C- (PKC- ): Its Unique Structure and Function

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon: multiple roles in the function of, and signaling mediated by, the cytoskeleton

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

PDGF initiates two distinct phases of protein kinase C activity that make unequal contributions to the G0 to S transition

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C as a stress sensor

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon makes the life and death decision

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

epsilonPKC confers acute tolerance to cerebral ischemic reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Regulation of novel protein kinase C epsilon by phosphorylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

From amplification to gene in thyroid cancer: a high-resolution mapped bacterial-artificial-chromosome resource for cancer chromosome aberrations guides gene discovery after comparative genome hybridization

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Hypertensive encephalopathy and the blood-brain barrier: is deltaPKC a gatekeeper?

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratum

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

The Coatomer Protein '-COP, a Selective Binding Protein (RACK) for Protein Kinase C

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon reveals importance of extrinsic apoptosis in preventing UV carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C-epsilon promotes survival of lung cancer cells by suppressing apoptosis through dysregulation of the mitochondrial caspase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Nuclear EGFR as novel therapeutic target: insights into nuclear translocation and function

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Changes in protein kinase C epsilon phosphorylation status and intracellular localization as 3T3 and 3T6 fibroblasts grow to confluency and quiescence: a role for phosphorylation at ser-729?

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

PKCepsilon is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Inhibition of novel protein kinase C-epsilon augments TRAIL-induced cell death in A549 lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C epsilon mediates the induction of P-glycoprotein in LNCaP prostate carcinoma cells

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Signal transduction of constitutively active protein kinase C epsilon.

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Variable expression of protein kinase C epsilon in human melanoma cells regulates sensitivity to TRAIL-induced apoptosis

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Constitutive association of c-N-Ras with c-Raf-1 and protein kinase C epsilon in latent signaling modules

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon-dependent MARCKS phosphorylation in neonatal and adult rat ventricular myocytes

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C isozymes as potential targets for anticancer therapy

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: overexpression of protein kinase Cepsilon in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Epsilon protein kinase C as a potential therapeutic target for the ischemic heart

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

PKC epsilon controls the traffic of beta1 integrins in motile cells

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C isozymes and substrates

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Endothelin-1 induction of Glut1 transcription in 3T3-L1 adipocytes involves distinct PKCepsilon- and p42/p44 MAPK-dependent pathways

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA.

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C epsilon is localized to the Golgi via its zinc-finger domain and modulates Golgi function

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C epsilon subcellular localization domains and proteolytic degradation sites. A model for protein kinase C conformational changes

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Hypoxia-induced nucleophosmin protects cell death through inhibition of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Rational design of a selective antagonist of epsilon protein kinase C derived from the selective allosteric agonist, pseudo-RACK peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C-epsilon protects MCF-7 cells from TNF-mediated cell death by inhibiting Bax translocation

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

The protein kinase complement of the human genome

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Restoration of resting sarcomere length after uniaxial static strain is regulated by protein kinase Cepsilon and focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Evidence that protein kinase Cepsilon mediates phorbol ester inhibition of calphostin C- and tumor necrosis factor-alpha-induced apoptosis in U937 histiocytic lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Critical role of diacylglycerol- and phospholipid-regulated protein kinase C epsilon in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Localization of protein kinases by anchoring proteins: a theme in signal transduction

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Regulation of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

A potential role for protein kinase C-epsilon in regulating megakaryocytic lineage commitment

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C activity as marker for colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Specific protein kinase C isoforms as transducers and modulators of insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Ceramide influences neurite outgrowth and neuroblastoma cell apoptosis regulated by novel protein kinase C isoforms

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Selective protein kinase C inhibitors and their applications

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https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Central role of protein kinase Cepsilon in constitutive activation of ERK1/2 and Rac1 in the malignant cells of hairy cell leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Peptide modulators of protein-protein interactions in intracellular signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF-7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C epsilon mediates angiotensin II-induced activation of beta1-integrins in cardiac fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Structural basis of protein kinase C isoform function

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon is important for migration of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C pharmacology: perspectives on therapeutic potentials as antidementic and cognitive agents

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C as a therapeutic target

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C-epsilon associates with the Raf-1 kinase and induces the production of growth factors that stimulate Raf-1 activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

A phase I/II study of LY900003, an antisense inhibitor of protein kinase C-alpha, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Overexpression of protein kinase C-{epsilon} in the mouse epidermis leads to a spontaneous myeloproliferative-like disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase C epsilon signals ultraviolet light-induced cutaneous damage and development of squamous cell carcinoma possibly through Induction of specific cytokines in a paracrine mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Integrin signaling links protein kinase Cepsilon to the protein kinase B/Akt survival pathway in recurrent prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Phosphorylation at Ser729 specifies a Golgi localisation for protein kinase C epsilon (PKCepsilon) in 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Phorbol ester-induced translocation of PKC epsilon to the nucleus in fibroblasts: identification of nuclear PKC epsilon-associating proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

PKC delta and epsilon in drug targeting and therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

PKCepsilon, via its regulatory domain and independently of its catalytic domain, induces neurite-like processes in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

Protein kinase Cepsilon actin-binding site is important for neurite outgrowth during neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2811%2970395-4

7 January 2021

10.1016/S1734-1140(11)70395-4

Identifiers

DOI

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24 August 2017

1 reference