Costimulatory blockade with monoclonal antibodies to induce alloanergy in donor lymphocytes (Q37863035)

24 August 2017

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title

Costimulatory blockade with monoclonal antibodies to induce alloanergy in donor lymphocytes (English)

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24 August 2017

Jeffrey K Davies

1

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24 August 2017

publication date

8 April 2011

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International Journal of Hematology

24 August 2017

published in

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24 August 2017

volume

93

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24 August 2017

issue

5

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24 August 2017

page(s)

594-601

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https://scigraph.springernature.com/pub.10.1007/s12185-011-0819-6

24 August 2017

exact match

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cites work

Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses

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Antiviral immunity and T-regulatory cell function are retained after selective alloreactive T-cell depletion in both the HLA-identical and HLA-mismatched settings

21 January 2018

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A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

21 January 2018

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Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

21 January 2018

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Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation

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21 January 2018

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21 January 2018

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21 January 2018

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Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies

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A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

21 January 2018

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Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

21 January 2018

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Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

21 January 2018

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Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia

21 January 2018

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Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies.

21 January 2018

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Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

21 January 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

21 January 2018

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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

21 January 2018

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Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

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Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

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Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies.

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Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

21 January 2018

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Transplantation of anergic histoincompatible bone marrow allografts

21 January 2018

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Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

21 January 2018

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12 December 2020

Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell

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12 December 2020

Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation

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12 December 2020

Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness

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12 December 2020

Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukaemic marrow transplant recipients

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12 December 2020

Increased risk of leukemia relapse with high-dose cyclosporine A after allogeneic marrow transplantation for acute leukemia

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12 December 2020

Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

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12 December 2020

Immune reconstitution without graft-versus-host disease after haemopoietic stem-cell transplantation: a phase 1/2 study

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12 December 2020

Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma

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12 December 2020

Specific elimination of alloreactive T cells by an anti-interleukin-2 receptor B chain-specific immunotoxin

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12 December 2020

p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

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12 December 2020

Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool

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12 December 2020

10.1007/S12185-011-0819-6

Identifiers

DOI

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24 August 2017

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