Epigenetic regulation of drug processing genes (Q37865530)

24 August 2017

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title

Epigenetic regulation of drug processing genes (English)

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24 August 2017

Curtis D Klaassen

1

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PubMed ID

21495869

24 August 2017

Hong Lu

series ordinal

2

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PubMed ID

21495869

24 August 2017

Julia Yue Cui

series ordinal

3

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24 August 2017

1 May 2011

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Toxicology Mechanisms and Methods

24 August 2017

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24 August 2017

21

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24 August 2017

4

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24 August 2017

312-324

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LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.

24 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Alternative-splicing forms of the major phase II conjugating UGT1A gene negatively regulate glucuronidation in human carcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Promoter methylation and differential expression of pi-class glutathione S-transferase in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Vitamin D receptor regulation of the steroid/bile acid sulfotransferase SULT2A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1α)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Molecular targets of epigenetic regulation and effectors of environmental influences

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Genetic and epigenetic regulation and expression signatures of glutathione S-transferases in developing mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Ontogenic expression of hepatic Ahr mRNA is associated with histone H3K4 di-methylation during mouse liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

MicroRNA-92b regulates expression of the oligopeptide transporter PepT1 in intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Promoter methylation of glutathione S-transferase pi1 and multidrug resistance gene 1 in bronchioloalveolar carcinoma and its correlation with DNA methyltransferase 1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

The 2006 Bernard B. Brodie Award Lecture. Cyp2e1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Dynamics of enhancer-promoter communication during differentiation-induced gene activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

DNA methylation profiles of organic anion transporting polypeptide 1B3 in cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Correlation between MDR1 methylation status in the promoter region and MDR1 genetic polymorphism in 194 healthy Chinese Han subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Hypothesizing that histone deacetylase inhibitors can be used to reverse multiple drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

CpG methylation of the mouse CYP1A2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Environmental epigenomics and disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Histone deacetylase inhibitor induction of P-glycoprotein transcription requires both histone deacetylase 1 dissociation and recruitment of CAAT/enhancer binding protein beta and pCAF to the promoter region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Xenobiotic transporters: ascribing function from gene knockout and mutation studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Sex differences in epigenetic regulation of the estrogen receptor-alpha promoter within the developing preoptic area

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Regulation of the UGT1A1 bilirubin-conjugating pathway: role of a new splicing event at the UGT1A locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylatio

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Transcriptional regulation of rat CYP2A3 by nuclear factor 1: identification of a novel NFI-A isoform, and evidence for tissue-selective interaction of NFI with the CYP2A3 promoter in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Vitamin D receptor as an intestinal bile acid sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Increased uptake of [¹²³I]meta-iodobenzylguanidine, [¹⁸F]fluorodopamine, and [³H]norepinephrine in mouse pheochromocytoma cells and tumors after treatment with the histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Human CYP2E1 is regulated by miR-378.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

MicroRNA regulates human vitamin D receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Site-specific cytosine methylation in S-COMT promoter in 31 brain regions with implications for studies involving schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Human liver-specific organic anion transporter-2 is a potent prognostic factor for human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Hepatocyte nuclear factor 1alpha gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Developmental expression of the major human hepatic CYP3A enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

In utero tobacco exposure epigenetically modifies placental CYP1A1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Effect of MDR1 gene promoter methylation in patients with ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

MicroRNAs regulate human hepatocyte nuclear factor 4alpha, modulating the expression of metabolic enzymes and cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Silencing of CYP1A1 expression in rabbits by DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Aberrant promoter methylation of the ABCG2 gene in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Estrogen signaling in livers of male mice with hepatocellular carcinoma induced by exposure to arsenic in utero

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Characterisation of CpG methylation in the upstream control region of mouse Nat2: evidence for a gene-environment interaction in a polymorphic gene implicated in folate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: let's call the whole thing off.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Epigenetic programming by maternal behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Epigenetic regulation of estrogen receptor alpha gene expression in the mouse cortex during early postnatal development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4alpha-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Induction of phase I, II and III drug metabolism/transport by xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Promoter hypomethylation of COMT in human placenta is not associated with the development of pre-eclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15376516.2011.562758

10.3109/15376516.2011.562758

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21495869