Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. (Q37880248)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21615707%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

review article

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title

Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif (English)

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2 February 2020

1

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2 February 2020

Stephen M. Lanier

series ordinal

3

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2 February 2020

author name string

S S Oner

series ordinal

2

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2 February 2020

publication date

5 July 2011

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2 February 2020

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2 February 2020

volume

204

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issue

2

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page(s)

202-218

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Thermodynamic Characterization of the Binding of Activator of G Protein Signaling 3 (AGS3) and Peptides Derived from AGS3 with Gαi1

2 February 2020

cites work

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Nucleus accumbens AGS3 expression drives ethanol seeking through G betagamma

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Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration

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Receptor-independent activators of heterotrimeric G-proteins.

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Human RAS superfamily proteins and related GTPases

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Control of embryonic spindle positioning and Galpha activity by C. elegans RIC-8.

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Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division

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Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits

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Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

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A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization

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Cell polarity and spindle orientation in the distal epithelium of embryonic lung

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Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium

21 January 2018

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Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neurons

21 January 2018

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Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON

21 January 2018

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Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells

21 January 2018

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Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.

21 January 2018

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GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling

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A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

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A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate

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21 January 2018

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21 January 2018

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21 January 2018

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Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i.

21 January 2018

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Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome.

21 January 2018

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Sensorimotor enhancement in mouse mutants lacking the Purkinje cell-specific Gi/o modulator, Pcp2(L7).

21 January 2018

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21 January 2018

Nitrosopeptide Mapping

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Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth

21 January 2018

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Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.

21 January 2018

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Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII.

21 January 2018

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LIM kinase-mediated cofilin phosphorylation during mitosis is required for precise spindle positioning.

21 January 2018

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Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression

21 January 2018

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Dexamethasone rapidly induces a novel ras superfamily member-related gene in AtT-20 cells

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Functional selectivity through protean and biased agonism: who steers the ship?

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Interaction of transducin-alpha with LGN, a G-protein modulator expressed in photoreceptor cells

21 January 2018

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RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity

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Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.

21 January 2018

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A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction

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A Purkinje cell specific GoLoco domain protein, L7/Pcp-2, modulates receptor-mediated inhibition of Cav2.1 Ca2+ channels in a dose-dependent manner

21 January 2018

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Asymmetric cell division: recent developments and their implications for tumour biology

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Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

21 January 2018

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Drosophila GoLoco-protein Pins is a target of Galpha(o)-mediated G protein-coupled receptor signaling

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

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Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor

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Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

21 January 2018

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RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

21 January 2018

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Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles

21 January 2018

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Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. Evidence for a novel nucleotide exchange factor

21 January 2018

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RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote

21 January 2018

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Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology

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G-protein signaling: back to the future

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Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells

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Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk

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The RGS14 GoLoco domain discriminates among Galphai isoforms

21 January 2018

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Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

21 January 2018

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Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.

21 January 2018

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The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors

21 January 2018

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AGS3 inhibits GDP dissociation from galpha subunits of the Gi family and rhodopsin-dependent activation of transducin

21 January 2018

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Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs

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Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.

21 January 2018

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Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.

21 January 2018

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Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai

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The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.

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Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.

21 January 2018

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Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins.

21 January 2018

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Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.

21 January 2018

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Raf-like Ras/Rap-binding domains in RGS12- and still-life-like signalling proteins

21 January 2018

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Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents

21 January 2018

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Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

21 January 2018

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G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth

21 January 2018

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Regulation of Golgi structure and secretion by receptor-induced G protein βγ complex translocation

21 January 2018

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The effect of RGS12 on PDGFbeta receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cells

21 January 2018

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G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

21 January 2018

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mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression

21 January 2018

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AGS3 and signal integration by Galpha(s)- and Galpha(i)-coupled receptors: AGS3 blocks the sensitization of adenylyl cyclase following prolonged stimulation of a Galpha(i)-coupled receptor by influencing processing of Galpha(i).

21 January 2018

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Accessory proteins for G proteins: partners in signaling.

21 January 2018

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Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma

21 January 2018

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Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43)

21 January 2018

1 reference

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Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel

21 January 2018

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The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

21 January 2018

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Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization

21 January 2018

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RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways

21 January 2018

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The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Identification and characterization of a G-protein regulatory motif in WAVE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

RapGAPs in brain: multipurpose players in neuronal Rap signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Receptor-independent activators of heterotrimeric G-protein signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Absence of neuroanatomical and behavioral deficits in L7/pcp-2-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

The Ras superfamily at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Does WAVE1 contain a GoLoco/GPR motif?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Return of the GDI: the GoLoco motif in cell division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of the dual GoLoco motif protein PCP-2 (Purkinje cell protein-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

RGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

A truncating mutation in GPSM2 is associated with recessive non-syndromic hearing loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Regulatory dissociation of Tctex-1 light chain from dynein complex is essential for the apical delivery of rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

LGN regulates mitotic spindle orientation during epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1748-1716.2011.02327.X

10.1111/J.1748-1716.2011.02327.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21615707%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference