LOX-1: a critical player in the genesis and progression of myocardial ischemia (Q37918860)

25 August 2017

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title

LOX-1: a critical player in the genesis and progression of myocardial ischemia (English)

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25 August 2017

Jingjun Lü

1

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PubMed ID

21847544

25 August 2017

Jawahar L Mehta

series ordinal

2

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25 August 2017

1 October 2011

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Cardiovascular Drugs and Therapy

25 August 2017

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25 August 2017

25

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25 August 2017

5

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25 August 2017

431-440

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The human gene encoding the lectin-type oxidized LDL receptor (OLR1) is a novel member of the natural killer gene complex with a unique expression profile

25 August 2017

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

An endothelial receptor for oxidized low-density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Activation of lectin-like oxidized low-density lipoprotein receptor-1 induces apoptosis in cultured neonatal rat cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Increased expression of lectin-like oxidized low density lipoprotein receptor-1 in initial atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Activation-dependent surface expression of LOX-1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Molecular dissection of angiotensin II-activated human LOX-1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Modulation of angiotensin II-mediated hypertension and cardiac remodeling by lectin-like oxidized low-density lipoprotein receptor-1 deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Human lectin-like oxidized low-density lipoprotein receptor-1 functions as a dimer in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Molecular imaging of atherosclerotic plaques targeted to oxidized LDL receptor LOX-1 by SPECT/CT and magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

3'UTR/T polymorphism of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is associated with modified anti-platelet activity of atorvastatin in hypercholesterolemic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

LOX-1 inhibition in myocardial ischemia-reperfusion injury: modulation of MMP-1 and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Role of NADPH oxidase in endothelial ischemia/reperfusion injury in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Postischemic inflammatory syndrome: a critical mechanism of progression in diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Anti-LOX-1 therapy in rats with diabetes and dyslipidemia: ablation of renal vascular and epithelial manifestations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Integrins, membrane-type matrix metalloproteinases and ADAMs: potential implications for cardiac remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

A quantitative gene expression profile of matrix metalloproteinases (MMPS) and their inhibitors (TIMPS) in the myocardium of patients with deteriorating heart failure requiring left ventricular assist device support.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

LOX-1 abrogation reduces myocardial ischemia-reperfusion injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Deletion of LOX-1 attenuates renal injury following angiotensin II infusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 in failing rat hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

G501C polymorphism of oxidized LDL receptor gene (OLR1) and ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

The 3'-UTR C>T polymorphism of the oxidized LDL-receptor 1 (OLR1) gene does not associate with coronary artery disease in Italian CAD patients or with the severity of coronary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

OLR1 gene and coronary artery disease/acute myocardial infarction: replication in an independently collected sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

Genotyping OLR1 Gene: A Genomic Biomarker for Cardiovascular Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-011-6329-1

10.1007/S10557-011-6329-1

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

21847544