Multifaceted roles of curcumin: two sides of a coin! (Q37937617)

25 August 2017

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title

Multifaceted roles of curcumin: two sides of a coin! (English)

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25 August 2017

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Dipshikha Chakravortty

series ordinal

4

object named as

Dipshikha Chakravortty

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25 August 2017

Sandhya A Marathe

1

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25 August 2017

Ishani Dasgupta

series ordinal

2

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25 August 2017

Divya Prakash Gnanadhas

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3

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25 August 2017

language of work or name

English

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publication date

27 September 2011

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Expert Opinion on Biological Therapy

25 August 2017

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25 August 2017

11

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25 August 2017

1485-1499

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25 August 2017

11

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Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment.

25 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin: the Indian solid gold

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin alleviates matrix metalloproteinase-3 and -9 activities during eradication of Helicobacter pylori infection in cultured cells and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Leishmanicidal effect of curcumin in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Resistance toLeishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Antimicrobial activity of curcumin against Helicobacter pylori isolates from India and during infections in mice.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-infected epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin suppresses constitutive activation of AP-1 by downregulation of JunD protein in HTLV-1-infected T-cell lines

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Increased production of matrix metalloproteinases in Helicobacter pylori-associated human gastritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Potential role for matrix metalloproteinase-3 in gastric ulcer healing

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

A curcumin-based 1-week triple therapy for eradication of Helicobacter pylori infection: something to learn from failure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Long-term use of an antiinflammatory, curcumin, suppressed type 1 immunity and exacerbated visceral leishmaniasis in a chronic experimental model

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin increases the pathogenicity of Salmonella enterica serovar Typhimurium in murine model

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Salmonella pathogenicity islands encoding type III secretion systems

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Regulation of Salmonella enterica serovar Typhimurium mntH transcription by H(2)O(2), Fe(2+), and Mn(2+).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

A SitABCD homologue from an avian pathogenic Escherichia coli strain mediates transport of iron and manganese and resistance to hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Inhibitory effect of curcumin on SOS functions induced by UV irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The immune system and the gut microbiota: friends or foes?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Latent activity of curcumin against leishmaniasis in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Reactive oxygen species and imbalance of calcium homeostasis contributes to curcumin induced programmed cell death in Leishmania donovani

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Cytotoxic effect of curcumin on Giardia lamblia trophozoites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The epigenetic control of antigenic variation in Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Computational screening of molecular targets in Plasmodium for novel non resistant anti-malarial drugs

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin-artemisinin combination therapy for malaria

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Artemisinins target the SERCA of Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Plasmodium chabaudi: efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Trypanocidal effects of curcumin in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Inhibition of human immunodeficiency virus type-1 integrase by curcumin

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Plant products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Proteasome inhibition reduces coxsackievirus B3 replication in murine cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin protects neuronal cells from Japanese encephalitis virus-mediated cell death and also inhibits infective viral particle formation by dysregulation of ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin has bright prospects for the treatment of inflammatory bowel disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1beta and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Modulation of neutrophil motility by curcumin: implications for inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin therapy in inflammatory bowel disease: a pilot study

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

REVIEW: Curcumin and Alzheimer's Disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

21 January 2018

The targets of curcumin.

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin-derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Through metal binding, curcumin protects against lead- and cadmium-induced lipid peroxidation in rat brain homogenates and against lead-induced tissue damage in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Glutathione, iron and Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Therapeutic approaches to mitochondrial dysfunction in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Beneficial role of curcumin in skin diseases

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Haem oxygenase-1: a novel player in cutaneous wound repair and psoriasis?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Innovations in the treatment of psoriasis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin impairs tumor suppressor p53 function in colon cancer cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Induction of apoptosis by curcumin and its implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin induces apoptosis-independent death in oesophageal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Prooxidant activity of curcumin: copper-dependent formation of 8-hydroxy-2'-deoxyguanosine in DNA and induction of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Flavan-3-ols and procyanidins protect liposomes against lipid oxidation and disruption of the bilayer structure.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Bioavailability of curcumin: problems and promises

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Efficacy and irritancy of enhancers on the in-vitro and in-vivo percutaneous absorption of curcumin

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Highly loaded, sustained-release microparticles of curcumin for chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin nanoparticles: preparation, characterization, and antimicrobial study

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

A novel solubility-enhanced curcumin formulation showing stability and maintenance of anticancer activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Highly active anticancer curcumin analogues

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2011.623124

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Design, synthesis and characterization of some bioactive conjugates of curcumin with glycine, glutamic acid, valine and demethylenated piperic acid and study of their antimicrobial and antiproliferative properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Effect of ascorbic acid and curcumin on quercetin-induced nuclear DNA damage, lipid peroxidation and protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Curcumin and its nano-formulation: the kinetics of tissue distribution and blood-brain barrier penetration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Manganese complexes of curcumin and its derivatives: evaluation for the radical scavenging ability and neuroprotective activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Synthesis and exploration of novel curcumin analogues as anti-malarial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Synthesis and anti-bacterial properties of mono-carbonyl analogues of curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Conjugation of curcumin onto hyaluronic acid enhances its aqueous solubility and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

[DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Structure–Activity Relationships for Antioxidant Activities of a Series of Flavonoids in a Liposomal System

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

Modulation of Liposomal Membrane Fluidity by Flavonoids and Isoflavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2011.623124

10.1517/14712598.2011.623124

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference