Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors (Q37943396)

25 August 2017

1 reference

title

Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors (English)

1 reference

25 August 2017

Jianning Ge

1

1 reference

PubMed ID

21981078

25 August 2017

Feng Shao

series ordinal

2

1 reference

25 August 2017

10 November 2011

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25 August 2017

Cellular Microbiology

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25 August 2017

13

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25 August 2017

12

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25 August 2017

1870-1880

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Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila.

25 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

IcmS-dependent translocation of SdeA into macrophages by the Legionella pneumophila type IV secretion system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Temporal resolution of two-tracked NF-kappaB activation by Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Lgt: a family of cytotoxic glucosyltransferases produced by Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Genome-scale identification of Legionella pneumophila effectors using a machine learning approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella effectors that promote nonlytic release from protozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A Legionella effector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

LidA, a translocated substrate of the Legionella pneumophila type IV secretion system, interferes with the early secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella eukaryotic-like type IV substrates interfere with organelle trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionnaires' disease: description of an epidemic of pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Molecular characterization of the Dot/Icm-translocated AnkH and AnkJ eukaryotic-like effectors of Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Proteomic analysis of growth phase-dependent expression of Legionella pneumophila proteins which involves regulation of bacterial virulence traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Protein kinase LegK2 is a type IV secretion system effector involved in endoplasmic reticulum recruitment and intracellular replication of Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila inhibits acidification of its phagosome in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The E Block motif is associated with Legionella pneumophila translocated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila proteins that regulate Rab1 membrane cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The transfer region of IncI1 plasmid R64: similarities between R64 tra and legionella icm/dot genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Characterisation of Legionella pneumophila phospholipases and their impact on host cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The Legionella pneumophila effector SidJ is required for efficient recruitment of endoplasmic reticulum proteins to the bacterial phagosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

LnaB: a Legionella pneumophila activator of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A bifunctional bacterial protein links GDI displacement to Rab1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Modulation of Rab GTPase function by a protein phosphocholine transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modified vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Interferons direct an effective innate response to Legionella pneumophila infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Indispensable role for the eukaryotic-like ankyrin domains of the ankyrin B effector of Legionella pneumophila within macrophages and amoebae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Attachment and fusion of endoplasmic reticulum with vacuoles containing Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Bacterial FIC Proteins AMP Up Infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Members of a Legionella pneumophila family of proteins with ExoU (phospholipase A) active sites are translocated to target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Conjugative transfer by the virulence system of Legionella pneumophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The fic domain: regulation of cell signaling by adenylylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

The response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

Identification of a hypervariable region containing new Legionella pneumophila Icm/Dot translocated substrates by using the conserved icmQ regulatory signature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01710.X

10.1111/J.1462-5822.2011.01710.X

21 January 2018

Identifiers

DOI

1 reference

release_lszhqr5aczboxpl425ll27mdz4

25 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lszhqr5aczboxpl425ll27mdz4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

21981078

1 reference

PubMed ID

21981078