Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease. (Q37946305)

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14 January 2020

title

Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease (English)

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14 January 2020

0 references

1 reference

1

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14 January 2020

Roger Walz

4

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14 January 2020

7

Richard L Doty

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14 January 2020

author name string

Aderbal S Aguiar

2

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14 January 2020

Filipe C Matheus

3

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14 January 2020

Layal Antoury

5

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14 January 2020

Rita Raisman-Vozari

6

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publication date

15 October 2011

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14 January 2020

published in

Neurotoxicity Research

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14 January 2020

volume

21

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14 January 2020

issue

1

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14 January 2020

page(s)

90-116

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https://scigraph.springernature.com/pub.10.1007/s12640-011-9281-8

14 January 2020

exact match

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1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Paraquat neurotoxicity is distinct from that of MPTP and rotenone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Transient parkinsonism in West Nile virus encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Gene-environment interactions in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Effect of local 6-OHDA and 5,6-DHT injections into the rat olfactory bulb on neophobia and learned aversion to a novel food.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Canine distemper virus uses both the anterograde and the hematogenous pathway for neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Spread of Venezuelan equine encephalitis virus in mice olfactory tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Neurobiology and treatment of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Neurochemical findings in the MPTP model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

The insecticide target in the PSST subunit of complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Parkinson's disease and exposure to agricultural work and pesticide chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Carrier-mediated processes in blood--brain barrier penetration and neural uptake of paraquat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Surprisingly rich projection from locus coeruleus to the olfactory bulb in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Delayed recognition memory in Parkinson's disease: a role for working memory?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Odor identification deficits are associated with increased risk of neuropsychiatric complications in patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Practice Parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Cadmium-metallothionein interactions in the olfactory pathways of rats and pikes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

The role of environmental toxins in the etiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Advances in environmental epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Olfactory uptake of manganese requires DMT1 and is enhanced by anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Loss of olfaction in de novo and treated Parkinson's disease: possible implications for early diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

The premotor phase of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

6-hydroxy-dopamine induced degeneration of central monoamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Evaluation of risk of Parkinson's disease in a cohort of licensed pesticide users.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Targeting programmed cell death in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Inhibitory effects of pesticides on proteasome activity: implication in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Multiple parallel memory systems in the brain of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

The possible role of iron in the etiopathology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Adenovirus-mediated gene transfer in olfactory neurons in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

From nose to brain: understanding transport capacity and transport rate of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9281-8

Influenza and Parkinson's disease

21 January 2018

1 reference

12 December 2020

Transport of intranasally instilled fine Fe2O3 particles into the brain: micro-distribution, chemical states, and histopathological observation

1 reference

12 December 2020

Time course of nigrostriatal degeneration in parkinson's disease. A detailed study of influential factors in human brain amine analysis

1 reference

12 December 2020

[A long duration follow-up study of Japanese encephalitis]

1 reference

12 December 2020

Histopathogenesis of mousepox. I. Respiratory infection.

1 reference

12 December 2020

Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias).

1 reference

12 December 2020

Glycoprotein D-negative pseudorabies virus can spread transneuronally via direct neuron-to-neuron transmission in its natural host, the pig, but not after additional inactivation of gE or gI.

1 reference

12 December 2020

Aluminum: a possible neurotoxic agent in Alzheimer's disease

1 reference

12 December 2020

Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease?

1 reference

12 December 2020

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

1 reference

12 December 2020

A rat model of Parkinson's disease induced by Japanese encephalitis virus.

1 reference

12 December 2020

Olfactory impairment in Parkinson's disease

1 reference

12 December 2020

Uptake of aluminium into central nervous system along nasal-olfactory pathways

1 reference

12 December 2020

Reactive dopamine metabolites and neurotoxicity: implications for Parkinson's disease

1 reference

12 December 2020

Selective anosmia in Parkinson's disease?

1 reference

12 December 2020

The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.

1 reference

12 December 2020

Manganese taken up into the CNS via the olfactory pathway in rats affects astrocytes

1 reference

12 December 2020

Olfactory function and Parkinson's disease in Southern Brazil

1 reference

12 December 2020

Mode of entry of a neurotropic arbovirus into the central nervous system. Reinvestigation of an old controversy

1 reference

12 December 2020

Susceptibility to a neurotropic virus and its changing distribution in the developing brain is a function of CNS maturity.

1 reference

12 December 2020

Deposition of aluminum in brain tissues of rats exposed to inhalation of aluminum acetylacetonate

1 reference

12 December 2020

Early diagnosis of Parkinson's disease

1 reference

12 December 2020

Parkinsonism due to predominant involvement of substantia nigra in Japanese encephalitis

1 reference

12 December 2020

Neuroprotective effect of ketamine/xylazine on two rat models of Parkinson's disease

1 reference

12 December 2020

Comparative studies on the mechanisms of paraquat and 1-methyl-4-phenylpyridine (MPP+) cytotoxicity

1 reference

12 December 2020

1 reference

12 December 2020

On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat

1 reference

12 December 2020

Transport and subcellular distribution of nickel in the olfactory system of pikes and rats

1 reference

12 December 2020

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

1 reference

12 December 2020

Lack of major olfactory dysfunction in MPTP-induced parkinsonism

1 reference

12 December 2020

Measles infection and Parkinson's disease

1 reference

12 December 2020

Olfactory primary neurons as a route of entry for toxic agents into the CNS

1 reference

12 December 2020

A dual effect of 1-methyl-4-phenylpyridinium (MPP+)-analogs on the respiratory chain of bovine heart mitochondria

1 reference

12 December 2020

Excessive iron accumulation in the brain: a possible potential risk of neurodegeneration in Parkinson's disease.

1 reference

12 December 2020

Calcium, magnesium and aluminum concentrations in Parkinson's disease.

1 reference

12 December 2020

Para-encephalitic parkinsonism. Report of an acute case due to coxsackie virus type B 2 and re-examination of the etiologic concepts of postencephalitic parkinsonism

1 reference

12 December 2020

Chronic MPTP treatment reproduces in baboons the differential vulnerability of mesencephalic dopaminergic neurons observed in Parkinson's disease

1 reference

12 December 2020

Chronic parkinsonism secondary to intranasal administration of a product of meperidine-analogue synthesis

1 reference

12 December 2020

Viral replication in olfactory receptor neurons and entry into the olfactory bulb and brain

1 reference

12 December 2020

Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry.

1 reference

12 December 2020

Uptake and transport of manganese in primary and secondary olfactory neurones in pike

1 reference

12 December 2020

Neuropathology of Parkinson's disease

1 reference

12 December 2020

Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration.

1 reference

12 December 2020

Depression in patients with Parkinson's disease

1 reference

12 December 2020

Neurofibrillary degeneration induced by systemic aluminum

1 reference

12 December 2020

Localization of herpes simplex virus in the trigeminal and olfactory systems of the mouse central nervous system during acute and latent infections by in situ hybridization

1 reference

12 December 2020

Olfactory function in essential tremor

1 reference

12 December 2020