Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system (Q37950792)

25 August 2017

Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system (English)

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25 August 2017

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Manuela Zaccolo

2

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author name string

Alessandra Stangherlin

series ordinal

1

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25 August 2017

28 October 2011

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American Journal of Physiology Heart and Circulatory Physiology

25 August 2017

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25 August 2017

302

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25 August 2017

2

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25 August 2017

H379-90

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A phosphodiesterase 2A isoform localized to mitochondria regulates respiration

25 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A toolkit for real-time detection of cAMP: insights into compartmentalized signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Calcium cycling and signaling in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic nucleotide-gated channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac proteins: multi-purpose cAMP targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac: a new cAMP target and new avenues in cAMP research

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Hormonally specific phosphorylation of cardiac troponin I and activation of glycogen phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Blotting and band-shifting: techniques for studying protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The cAMP binding protein Epac regulates cardiac myofilament function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Protein kinase A type I and type II define distinct intracellular signaling compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Structure and function of cyclic nucleotide-dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac: defining a new mechanism for cAMP action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Primary structure and function of an A kinase anchoring protein associated with calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Isoforms of cyclic nucleotide phosphodiesterase PDE3 and their contribution to cAMP hydrolytic activity in subcellular fractions of human myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Hormonally specific expression of cardiac protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Identification and functional characterization of protein kinase A-catalyzed phosphorylation of potassium channel Kv1.2 at serine 449.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with tissue-specific binding proteins including microtubule-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac mediates beta-adrenergic receptor-induced cardiomyocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A complex phosphodiesterase system controls beta-adrenoceptor signalling in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The effect of histamine and cyclic adenosine monophosphate on myosin light chain phosphorylation in human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The molecular basis for protein kinase A anchoring revealed by solution NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Compartmentalized cyclic adenosine 3',5'-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Distinct phosphodiesterase-4D variants integrate into protein kinase A-based signaling complexes in cardiac and vascular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Myocardial cyclic AMP and norepinephrine content in human heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cloning and characterization of an olfactory cyclic nucleotide-gated channel expressed in mouse heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A complex between FAK, RACK1, and PDE4D5 controls spreading initiation and cancer cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

cGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac Myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Local termination of 3'-5'-cyclic adenosine monophosphate signals: the role of A kinase anchoring protein-tethered phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Structural framework for the protein kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Myocyte adrenoceptor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Expression of cyclic nucleotide-gated cation channels in airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

Imaging signal transduction in living cells with GFP-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

The potential use of AKAP18δ as a drug target in heart failure patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00766.2011

10.1152/AJPHEART.00766.2011

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

22037184