In vitro three-dimensional (3D) models in cancer research: an update (Q37967634)

26 August 2017

title

In vitro three-dimensional (3D) models in cancer research: an update (English)

1 reference

26 August 2017

Lauren C Kimlin

1

1 reference

26 August 2017

Giovanna Casagrande

series ordinal

2

1 reference

26 August 2017

Victoria M Virador

series ordinal

3

1 reference

26 August 2017

publication date

7 December 2011

1 reference

26 August 2017

published in

Molecular Carcinogenesis

1 reference

26 August 2017

volume

52

1 reference

26 August 2017

issue

3

1 reference

26 August 2017

page(s)

167-182

1 reference

Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization

26 August 2017

cites work

1 reference

Breast cancer cell lines carry cell line-specific genomic alterations that are distinct from aberrations in breast cancer tissues: comparison of the CGH profiles between cancer cell lines and primary cancer tissues

21 January 2018

1 reference

21 January 2018

Mouse Models of Cancer

1 reference

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

21 January 2018

1 reference

Cutaneous melanoma in genetically modified animals

21 January 2018

1 reference

Tumor engineering: the other face of tissue engineering

21 January 2018

1 reference

Melanocytes: from morphology to application.

21 January 2018

1 reference

Three-dimensional culture models of normal and malignant breast epithelial cells

21 January 2018

1 reference

The third dimension bridges the gap between cell culture and live tissue

21 January 2018

1 reference

MG-63 human osteosarcoma cells grown in monolayer and as three-dimensional tumor spheroids present a different metabolic profile: a (1)H NMR study.

21 January 2018

1 reference

Integrin expression on colorectal tumor cells growing as monolayers, as multicellular tumor spheroids, or in nude mice

21 January 2018

1 reference

Cytotoxicity of sphingoid marine compound analogs in mono- and multilayered solid tumor cell cultures

21 January 2018

1 reference

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

21 January 2018

1 reference

Engineering tumors with 3D scaffolds

21 January 2018

1 reference

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

21 January 2018

1 reference

21 January 2018

The Hallmarks of Cancer

1 reference

Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation

21 January 2018

1 reference

Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis

21 January 2018

1 reference

Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell–like Properties in Breast Cancer Cells

21 January 2018

1 reference

Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

21 January 2018

1 reference

Cell and environment interactions in tumor microregions: the multicell spheroid model

21 January 2018

1 reference

Induction of apoptosis in the centre of multicellular tumour spheroids of colorectal adenocarcinomas--involvement of CD95 pathway and differentiation

21 January 2018

1 reference

Three-dimensional bioreactor cultures: a useful dynamic model for the study of cellular interactions.

21 January 2018

1 reference

Epithelial-mesenchymal transition in development and cancer

21 January 2018

1 reference

Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment

21 January 2018

1 reference

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

Multilineage potential of adult human mesenchymal stem cells

21 January 2018

1 reference

Isolation of a mesenchymal cell population from murine dermis that contains progenitors of multiple cell lineages

21 January 2018

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

21 January 2018

1 reference

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

21 January 2018

1 reference

Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells

21 January 2018

1 reference

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

21 January 2018

1 reference

E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents

21 January 2018

1 reference

Determinants of leader cells in collective cell migration

21 January 2018

1 reference

MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.

21 January 2018

1 reference

Isolation of a tumor factor responsible for angiogenesis

21 January 2018

1 reference

Judah Folkman, a pioneer in the study of angiogenesis

21 January 2018

1 reference

Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: a role for T-cadherin in tumor angiogenesis

21 January 2018

1 reference

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

21 January 2018

1 reference

Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front

21 January 2018

1 reference

In situ force mapping of mammary gland transformation

21 January 2018

1 reference

Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy

21 January 2018

1 reference

A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression

21 January 2018

1 reference

Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression

21 January 2018

1 reference

Tetraspanin CD151 regulates growth of mammary epithelial cells in three-dimensional extracellular matrix: implication for mammary ductal carcinoma in situ.

21 January 2018

1 reference

Adenoviral gene transfer of beta3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma

21 January 2018

1 reference

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

21 January 2018

1 reference

Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge?

21 January 2018

1 reference

Nemosis, a novel way of fibroblast activation, in inflammation and cancer

21 January 2018

1 reference

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

21 January 2018

1 reference

Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment

21 January 2018

1 reference

Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis

21 January 2018

1 reference

Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis

21 January 2018

1 reference

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

21 January 2018

1 reference

Cancer associated fibroblasts in cancer pathogenesis

21 January 2018

1 reference

Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by matrigel and fibroblasts

21 January 2018

1 reference

The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells

21 January 2018

1 reference

Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture

21 January 2018

1 reference

The role of endothelial-to-mesenchymal transition in cancer progression

21 January 2018

1 reference

Targeting breast cancer stem cells

21 January 2018

1 reference

Cancer stem cells: an old idea--a paradigm shift

21 January 2018

1 reference

Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy

21 January 2018

1 reference

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

Cells of origin in cancer

21 January 2018

1 reference

Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis

21 January 2018

1 reference

The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis

21 January 2018

1 reference

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

21 January 2018

1 reference

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

21 January 2018

1 reference

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

21 January 2018

1 reference

Isolation and identification of cancer stem cells from human osteosarcom by serum-free three-dimensional culture combined with anticancer drugs

21 January 2018

1 reference

A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma

21 January 2018

1 reference

Permanent phenotypic and genotypic changes of prostate cancer cells cultured in a three-dimensional rotating-wall vessel

21 January 2018

1 reference

Life isn't flat: taking cancer biology to the next dimension

21 January 2018

1 reference

A model of primary culture of colorectal cancer and liver metastasis to predict chemosensitivity

21 January 2018

1 reference

Chemosensitivity assessed by collagen gel droplet embedded culture drug sensitivity test, and MDR1, MRP1, and MRP2 mRNA expression in human colorectal adenocarcinomas

21 January 2018

1 reference

A melanocyte-keratinocyte coculture model to assess regulators of pigmentation in vitro

21 January 2018

1 reference

The use of 3-D cultures for high-throughput screening: the multicellular spheroid model

21 January 2018

1 reference

A novel three-dimensional model to quantify metastatic melanoma invasion

21 January 2018

1 reference

The genetics and genomics of cancer

21 January 2018

1 reference

21 January 2018

Epigenetics in cancer

1 reference

Signatures of mutation and selection in the cancer genome

21 January 2018

1 reference

Automated local bright feature image analysis of nuclear protein distribution identifies changes in tissue phenotype

21 January 2018

1 reference

Influence of the microenvironment on melanoma cell fate determination and phenotype.

21 January 2018

1 reference

Cell locomotion and focal adhesions are regulated by substrate flexibility

21 January 2018

1 reference

Matrix elasticity directs stem cell lineage specification

21 January 2018

1 reference

Matrix crosslinking forces tumor progression by enhancing integrin signaling

21 January 2018

1 reference

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

21 January 2018

1 reference

Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes

21 January 2018

1 reference

Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels

21 January 2018

1 reference

Occluding junctions and cell behavior in primary cultures of normal and neoplastic mammary gland cells

21 January 2018

1 reference

Tissue-engineered three-dimensional tumor models to study tumor angiogenesis.

21 January 2018

1 reference

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.

21 January 2018

1 reference

Spindle epithelial tumor with thymus-like differentiation: a case report and review of the literature

21 January 2018

1 reference

Paper-supported 3D cell culture for tissue-based bioassays

21 January 2018

1 reference

Apoptosis in a tissue-like culture model of human colorectal adenoma cells

21 January 2018

1 reference

Dynamics of differentiation in human epidermoid squamous carcinoma cells (A431) with continuous, long-term γ-IFN treatment

21 January 2018

1 reference

Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction

21 January 2018

1 reference

Use of microgravity bioreactors for development of an in vitro rat salivary gland cell culture model

21 January 2018

1 reference

Microgravity culture reduces apoptosis and increases the differentiation of a human colorectal carcinoma cell line

21 January 2018

1 reference

Cell cycle effects of radiation on human bronchial epithelium and lung carcinoma cells in monolayer cultures and a three-dimensional co-culture system.

21 January 2018

1 reference

Fibroblast-directed expression and localization of 92-kDa type IV collagenase along the tumor-stroma interface in an in vitro three-dimensional model of human squamous cell carcinoma

21 January 2018

1 reference

An in vitro three-dimensional model of primary human cutaneous squamous cell carcinoma

21 January 2018

1 reference

E-cadherin suppression accelerates squamous cell carcinoma progression in three-dimensional, human tissue constructs.

21 January 2018

1 reference

Effects of photodynamic therapy evaluated in a novel three-dimensional squamous cell carcinoma organ construct of the skin

21 January 2018

1 reference

Growth inhibition by interferon beta and gamma of MDA 886Ln monolayer cells and multicellular tumor spheroids. A differentiation therapy model for squamous cell carcinoma.

21 January 2018

1 reference

Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes.

21 January 2018

1 reference

Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture

21 January 2018

1 reference

Participation of liver cancer stem/progenitor cells in tumorigenesis of scirrhous hepatocellular carcinoma--human and cell culture study

21 January 2018

1 reference

A novel, rapid strategy to form dendritomas from human dendritic cells and hepatocellular carcinoma cell line HCCLM3 cells using mature dendritic cells derived from human peripheral blood CD14+ monocytes within 48 hours of in vitro culture

21 January 2018

1 reference

Chitosan-alginate scaffold culture system for hepatocellular carcinoma increases malignancy and drug resistance.

21 January 2018

1 reference

Morphological changes and molecular expressions of hepatocellular carcinoma cells in three-dimensional culture model

21 January 2018

1 reference

Identification of an active site of EMMPRIN for the augmentation of matrix metalloproteinase-1 and -3 expression in a co-culture of human uterine cervical carcinoma cells and fibroblasts

21 January 2018

1 reference

Proteasome inhibitors induce death but activate NF-kappaB on endometrial carcinoma cell lines and primary culture explants

21 January 2018

1 reference

An assessment of the effects of steroid hormones and antiestrogens on short-term organ culture of human endometrial carcinoma

21 January 2018

1 reference

A human colorectal explant culture to evaluate topical microbicides for the prevention of HIV infection

21 January 2018

1 reference

The monolayer and organ culture of human colorectal carcinomata and the associated "normal" colonic mucosa and their production of carcinoembryonic antigens

21 January 2018

1 reference

Changes in the DNA ploidy patterns of human colorectal carcinomas, subsequent to culture or xenografting

21 January 2018

1 reference

Activation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating system

21 January 2018

1 reference

A novel organotypic model mimics the tumor microenvironment

21 January 2018

1 reference

Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth

21 January 2018

1 reference

Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis

21 January 2018

1 reference

Three-dimensional spheroid cultures of human prostate cancer cell lines.

21 January 2018

1 reference

Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures

21 January 2018

1 reference

Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34+ cells

21 January 2018

1 reference

Three-dimensional culturing of the Hodgkin lymphoma cell-line L1236 induces a HL tissue-like gene expression pattern

21 January 2018

1 reference

The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia

21 January 2018

1 reference

A novel three-dimensional culture system allows prolonged culture of functional human granulosa cells and mimics the ovarian environment.

21 January 2018

1 reference

Identification of virus resistant tumor cell subpopulations in three-dimensional uveal melanoma cultures.

21 January 2018

1 reference

Growth and survival signalling in B16F10 melanoma cells in 3D culture.

21 January 2018

1 reference

Effects of Three‐Dimensional Culturing on Osteosarcoma Cells Grown in a Fibrous Matrix: Analyses of Cell Morphology, Cell Cycle, and Apoptosis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MC.21844

1 reference

26 August 2017

1 reference