Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis (Q37973279)

26 August 2017

Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis (English)

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26 August 2017

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Marc H G P Raaijmakers

series ordinal

1

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26 August 2017

6 January 2012

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International Journal of Hematology

26 August 2017

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26 August 2017

95

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26 August 2017

1

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26 August 2017

17-25

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https://scigraph.springernature.com/pub.10.1007/s12185-011-1001-x

26 August 2017

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12 December 2020

Focal adhesion protein abnormalities in myelodysplastic mesenchymal stromal cells

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12 December 2020

Elevated thrombopoietin serum concentrations in myelodysplasias

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NOD/SCID mice transplanted with marrow from patients with myelodysplastic syndrome (MDS) show long-term propagation of normal but not clonal human precursors

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12 December 2020

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12 December 2020

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Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q- syndrome

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

CD34+ progenitors from MDS patients are unresponsive to SDF-1, despite high levels of SDF-1 in bone marrow plasma

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12 December 2020

Defective Notch activation in microenvironment leads to myeloproliferative disease

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12 December 2020

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12 December 2020

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development

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12 December 2020

Bone marrow stroma from refractory anemia of myelodysplastic syndrome is defective in its ability to support normal CD34-positive cell proliferation and differentiation in vitro

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12 December 2020

Inappropriate Notch activity and limited mesenchymal stem cell plasticity in the bone marrow of patients with myelodysplastic syndromes

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12 December 2020

MDS: a stem cell disorder--but what exactly is wrong with the primitive hematopoietic cells in this disease?

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12 December 2020

Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche

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12 December 2020

10.1007/S12185-011-1001-X

Identifiers

DOI

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26 August 2017

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PubMed ID

22218882