Severe asthma: from characteristics to phenotypes to endotypes (Q37976476)

26 August 2017

Severe asthma: from characteristics to phenotypes to endotypes (English)

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26 August 2017

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S Wenzel

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26 August 2017

18 January 2012

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Clinical & Experimental Allergy

26 August 2017

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26 August 2017

42

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26 August 2017

5

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26 August 2017

650-658

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Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study

26 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Design and baseline characteristics of the epidemiology and natural history of asthma: Outcomes and Treatment Regimens (TENOR) study: a large cohort of patients with severe or difficult-to-treat asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Multi-symptom asthma is closely related to nasal blockage, rhinorrhea and symptoms of chronic rhinosinusitis-evidence from the West Sweden Asthma Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Multi-symptom asthma as an indication of disease severity in epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

A large-scale, consortium-based genomewide association study of asthma

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Cluster analysis and clinical asthma phenotypes.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Identifying adult asthma phenotypes using a clustering approach

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

The Melbourne Asthma Study: 1964-1999.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Childhood factors associated with asthma remission after 30 year follow up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

A sequence variant on 17q21 is associated with age at onset and severity of asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Increased sputum and bronchial biopsy IL-13 expression in severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

T lymphocytes that infiltrate nasal polyps have a specialized phenotype and produce a mixed TH1/TH2 pattern of cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled corticosteroids. Asthma and Allergy Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Mepolizumab and exacerbations of refractory eosinophilic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

"Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

A randomized trial of itraconazole in allergic bronchopulmonary aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Qualitative analysis of high-resolution CT scans in severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Clarithromycin targets neutrophilic airway inflammation in refractory asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Asthma and cigarette smoking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Effects of smoking cessation on lung function and airway inflammation in smokers with asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Short and long-term effects of cigarette smoking independently influence exhaled nitric oxide concentration in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2222.2011.03929.X

10.1111/J.1365-2222.2011.03929.X

21 January 2018

Identifiers

DOI

1 reference

release_su7l3z2ftvhddm5lbketrd2qkm

26 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/su7l3z2ftvhddm5lbketrd2qkm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

22251060

1 reference

PubMed ID

22251060