RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation (Q37987044)

26 August 2017

RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation (English)

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26 August 2017

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T Kanai

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Y Mikami

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T Sujino

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T Hisamatsu

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26 August 2017

T Hibi

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22 February 2012

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5

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3

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240-247

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https://scigraph.springernature.com/pub.10.1038/mi.2012.6

26 August 2017

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cites work

Unravelling the pathogenesis of inflammatory bowel disease

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Interleukin-17 and type 17 helper T cells

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Induction and effector functions of T(H)17 cells.

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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Th17 cell differentiation: the long and winding road

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

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A rush to judgment on Th17

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Increased expression of interleukin 17 in inflammatory bowel disease

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IL-23/IL-17 immunity as a hallmark of Crohn's disease

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IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

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Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease.

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Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease

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Regulation of gut inflammation and th17 cell response by interleukin-21.

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Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

21 January 2018

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The increased expression of IL-23 in inflammatory bowel disease promotes intraepithelial and lamina propria lymphocyte inflammatory responses and cytotoxicity

21 January 2018

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Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.

21 January 2018

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

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Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

21 January 2018

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IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

21 January 2018

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Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

21 January 2018

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IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

21 January 2018

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Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

21 January 2018

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RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

21 January 2018

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Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

21 January 2018

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A protective function for interleukin 17A in T cell-mediated intestinal inflammation

21 January 2018

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

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Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

21 January 2018

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New insights into the differentiation and function of T follicular helper cells.

21 January 2018

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IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

21 January 2018

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

21 January 2018

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Nuclear reprogramming to a pluripotent state by three approaches

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Plasticity of CD4+ T cell lineage differentiation.

21 January 2018

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Late developmental plasticity in the T helper 17 lineage

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Intestinal effector T cells in health and disease.

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Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells.

21 January 2018

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Interleukin-23 drives intestinal inflammation through direct activity on T cells

21 January 2018

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The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

21 January 2018

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Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

21 January 2018

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CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

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Innate IL-17-producing cells: the sentinels of the immune system

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The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

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Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity

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Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes

21 January 2018

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Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

21 January 2018

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Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

21 January 2018

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Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

21 January 2018

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Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells

21 January 2018

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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

21 January 2018

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IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses

21 January 2018

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IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease

21 January 2018

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Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.

21 January 2018

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Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells.

21 January 2018

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Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

21 January 2018

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Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD

21 January 2018

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7 January 2021

Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis

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7 January 2021

Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

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7 January 2021

Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice

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7 January 2021

Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis

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7 January 2021

Identifiers

DOI

10.1038/MI.2012.6

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Dimensions Publication ID

26 August 2017

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