Optogenetic investigation of neural circuits underlying brain disease in animal models. (Q37994954)

PubMed publication ID

22430017

26 August 2017

title

Optogenetic investigation of neural circuits underlying brain disease in animal models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

1 reference

2

Karl Deisseroth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

author name string

Kay M Tye

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

language of work or name

English

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publication date

20 March 2012

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PubMed publication ID

22430017

Nature Reviews Neuroscience

26 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

volume

13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

page(s)

251-266

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

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Next-generation optical technologies for illuminating genetically targeted brain circuits

31 March 2020

1 reference

The microbial opsin family of optogenetic tools

31 March 2020

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Temporally precise in vivo control of intracellular signalling

31 March 2020

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Millisecond-timescale, genetically targeted optical control of neural activity

31 March 2020

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Optogenetics in neural systems

31 March 2020

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The development and application of optogenetics

31 March 2020

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Optogenetic investigation of neural circuits in vivo

31 March 2020

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An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology

31 March 2020

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Optogenetic manipulation of neural circuitry in vivo.

31 March 2020

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Remote control of behavior through genetically targeted photostimulation of neurons

31 March 2020

1 reference

Channelrhodopsin-1: a light-gated proton channel in green algae.

31 March 2020

1 reference

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

31 March 2020

1 reference

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

31 March 2020

1 reference

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

31 March 2020

1 reference

Molecular and cellular approaches for diversifying and extending optogenetics

31 March 2020

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Bi-stable neural state switches

31 March 2020

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Multimodal fast optical interrogation of neural circuitry

31 March 2020

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High-performance genetically targetable optical neural silencing by light-driven proton pumps

31 March 2020

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Ultrafast optogenetic control.

31 March 2020

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Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

31 March 2020

1 reference

A simple head-mountable LED device for chronic stimulation of optogenetic molecules in freely moving mice

31 March 2020

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Controlling neuronal activity

31 March 2020

1 reference

An optogenetic toolbox designed for primates

31 March 2020

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Neural substrates of awakening probed with optogenetic control of hypocretin neurons

31 March 2020

1 reference

Multi-site optical excitation using ChR2 and micro-LED array

31 March 2020

1 reference

A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping

31 March 2020

1 reference

High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression

31 March 2020

1 reference

Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning

31 March 2020

1 reference

In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2.

31 March 2020

1 reference

Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

31 March 2020

1 reference

A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex.

31 March 2020

1 reference

Optetrode: a multichannel readout for optogenetic control in freely moving mice

31 March 2020

1 reference

Integrated device for combined optical neuromodulation and electrical recording for chronic in vivo applications.

31 March 2020

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Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement

31 March 2020

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Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

31 March 2020

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Optical probing of neuronal circuits with calcium indicators

31 March 2020

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Optogenetics meets optical wavefront shaping

31 March 2020

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Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections

31 March 2020

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The subcellular organization of neocortical excitatory connections

31 March 2020

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Lateral competition for cortical space by layer-specific horizontal circuits

31 March 2020

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Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution

31 March 2020

1 reference

Improved expression of halorhodopsin for light-induced silencing of neuronal activity

31 March 2020

1 reference

eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications

31 March 2020

1 reference

Characterization of engineered channelrhodopsin variants with improved properties and kinetics

31 March 2020

1 reference

Neocortical excitation/inhibition balance in information processing and social dysfunction

31 March 2020

1 reference

Imaging synaptic inhibition with the genetically encoded chloride indicator Clomeleon

31 March 2020

1 reference

Cholinergic interneurons control local circuit activity and cocaine conditioning

31 March 2020

1 reference

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

31 March 2020

1 reference

Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior

31 March 2020

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Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

31 March 2020

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Driving fast-spiking cells induces gamma rhythm and controls sensory responses

31 March 2020

1 reference

Optical deconstruction of parkinsonian neural circuitry

31 March 2020

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Amygdala circuitry mediating reversible and bidirectional control of anxiety

31 March 2020

1 reference

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

31 March 2020

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Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

31 March 2020

1 reference

Selective viral vector transduction of ErbB4 expressing cortical interneurons in vivo with a viral receptor-ligand bridge protein.

31 March 2020

1 reference

Targeted entry via somatostatin receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to those of wild-type viral glycoproteins

31 March 2020

1 reference

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

31 March 2020

1 reference

Multiwaveguide implantable probe for light delivery to sets of distributed brain targets

31 March 2020

1 reference

A wirelessly powered and controlled device for optical neural control of freely-behaving animals

31 March 2020

1 reference

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

31 March 2020

1 reference

Efficacy of drug treatments for generalised anxiety disorder: systematic review and meta-analysis

31 March 2020

1 reference

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

31 March 2020

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Fear and the human amygdala.

31 March 2020

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The role of the amygdala in fear and anxiety

31 March 2020

1 reference

Emotion: clues from the brain

31 March 2020

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The Amygdala, Fear, and Memory

31 March 2020

1 reference

Synaptic mechanisms of associative memory in the amygdala.

31 March 2020

1 reference

Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala

31 March 2020

1 reference

The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning

31 March 2020

1 reference

Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala

31 March 2020

1 reference

New vistas on amygdala networks in conditioned fear

31 March 2020

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Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning.

31 March 2020

1 reference

Rethinking the fear circuit: the central nucleus of the amygdala is required for the acquisition, consolidation, and expression of Pavlovian fear conditioning.

31 March 2020

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Selective erasure of a fear memory

31 March 2020

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Genetic dissection of an amygdala microcircuit that gates conditioned fear

31 March 2020

1 reference

Encoding of conditioned fear in central amygdala inhibitory circuits

31 March 2020

1 reference

Post-traumatic stress disorder

31 March 2020

1 reference

Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and future

31 March 2020

1 reference

Fear extinction in rats: implications for human brain imaging and anxiety disorders

31 March 2020

1 reference

Contextual fear, gestalt memories, and the hippocampus

31 March 2020

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Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning

31 March 2020

1 reference

Memory--a century of consolidation

31 March 2020

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Consolidation of CS and US representations in associative fear conditioning

31 March 2020

1 reference

The organization of recent and remote memories

31 March 2020

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New circuits for old memories: the role of the neocortex in consolidation

31 March 2020

1 reference

Independent cellular processes for hippocampal memory consolidation and reconsolidation

31 March 2020

1 reference

Dynamics of retrieval strategies for remote memories.

31 March 2020

1 reference

Drugs of abuse: anatomy, pharmacology and function of reward pathways

31 March 2020

1 reference

Drug-activation of brain reward pathways

31 March 2020

1 reference

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

31 March 2020

1 reference

The neural basis of drug craving: an incentive-sensitization theory of addiction

31 March 2020

1 reference

The neuroscience of natural rewards: relevance to addictive drugs.

31 March 2020

1 reference

A neural substrate of prediction and reward

31 March 2020

1 reference

The dopamine hypothesis of reward: past and current status

31 March 2020

1 reference

What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?

31 March 2020

1 reference

The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking

31 March 2020

1 reference

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

31 March 2020

1 reference

Basolateral amygdala neurons facilitate reward-seeking behavior by exciting nucleus accumbens neurons

31 March 2020

1 reference

Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex

31 March 2020

1 reference

Firing of nucleus accumbens neurons during the consummatory phase of a discriminative stimulus task depends on previous reward predictive cues

31 March 2020

1 reference

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

31 March 2020

1 reference

Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

31 March 2020

1 reference

Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain

31 March 2020

1 reference

Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling

31 March 2020

1 reference

Orbitofrontal cortex and basolateral amygdala encode expected outcomes during learning

31 March 2020

1 reference

Orbitofrontal cortex, associative learning, and expectancies

31 March 2020

1 reference

Rapid strengthening of thalamo-amygdala synapses mediates cue-reward learning

31 March 2020

1 reference

Methylphenidate facilitates learning-induced amygdala plasticity

31 March 2020

1 reference

A comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats.

31 March 2020

1 reference

Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward.

31 March 2020

1 reference

Dissociation of the role of nucleus accumbens dopamine in responding to reward-predictive cues and waiting for reward

31 March 2020

1 reference

Prefrontal cortical cell firing during maintenance, extinction, and reinstatement of goal-directed behavior for natural reward

31 March 2020

1 reference

Amygdala neural encoding of the absence of reward during extinction.

31 March 2020

1 reference

Amygdala neurons differentially encode motivation and reinforcement

31 March 2020

1 reference

Subsecond dopamine release promotes cocaine seeking.

31 March 2020

1 reference

Enhanced sucrose and cocaine self-administration and cue-induced drug seeking after loss of VGLUT2 in midbrain dopamine neurons in mice.

31 March 2020

1 reference

Research: Methods, Mechanisms, and Causes Introduction

31 March 2020

1 reference

Dopamine, depression and antidepressants

31 March 2020

1 reference

The compliance with antidepressants in general practice

31 March 2020

1 reference

The effects of adherence to antidepressant treatment guidelines on relapse and recurrence of depression.

31 March 2020

1 reference

Deep brain stimulation for treatment-resistant depression

31 March 2020

1 reference

Modulating limbic-cortical circuits in depression: targets of antidepressant treatments

31 March 2020

1 reference

Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex

31 March 2020

1 reference

Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide

31 March 2020

1 reference

Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons.

31 March 2020

1 reference

Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice

31 March 2020

1 reference

High-speed imaging reveals neurophysiological links to behavior in an animal model of depression

31 March 2020

1 reference

Hippocampal volume reduction in major depression.

31 March 2020

1 reference

Adult hippocampal neurogenesis in depression

31 March 2020

1 reference

The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death

31 March 2020

1 reference

Quantitative MRI of the hippocampus and amygdala in severe depression

31 March 2020

1 reference

Amygdala core nuclei volumes are decreased in recurrent major depression

31 March 2020

1 reference

Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study

31 March 2020

1 reference

Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression: related and independent features.

31 March 2020

1 reference

In vivo evidence for the involvement of dopamine-D2 receptors in striatum and anterior cingulate gyrus in major depression.

31 March 2020

1 reference

Stress-induced depressive behaviors are correlated with Par-4 and DRD2 expression in rat striatum

31 March 2020

1 reference

Lower dopamine transporter binding potential in striatum during depression

31 March 2020

1 reference

Involvement of dopamine receptors in the antidepressant-like effect of melatonin in the tail suspension test.

31 March 2020

1 reference

Dopamine and depression: A review of recent evidence. II. Theoretical approaches

31 March 2020

1 reference

Deep brain stimulation of the ventral capsule/ventral striatum for treatment-resistant depression.

31 March 2020

1 reference

Serotonin-Containing Neurons in Brain: Depression of Firing by Monoamine Oxidase Inhibitors

31 March 2020

1 reference

Serotonin brain circuits involved in major depression and suicide

31 March 2020

1 reference

Review of pharmacological treatment in mood disorders and future directions for drug development.

31 March 2020

1 reference

Anxiety in high-functioning children with autism

31 March 2020

1 reference

Defining autism spectrum disorders.

31 March 2020

1 reference

Molecular pathology of schizophrenia: more than one disease process?

31 March 2020

1 reference

A diagnostic interview: the schedule for affective disorders and schizophrenia

31 March 2020

1 reference

The positive and negative syndrome scale (PANSS) for schizophrenia

31 March 2020

1 reference

Altered Excitatory-Inhibitory Balance in the NMDA-Hypofunction Model of Schizophrenia

31 March 2020

1 reference

Alterations of cortical GABA neurons and network oscillations in schizophrenia.

31 March 2020

1 reference

Pathophysiologically based treatment interventions in schizophrenia

31 March 2020

1 reference

Optogenetic control of epileptiform activity

31 March 2020

1 reference

A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsy

31 March 2020

1 reference

The Intense World Theory – A Unifying Theory of the Neurobiology of Autism

31 March 2020

1 reference

A computational model for cerebral cortical dysfunction in autism spectrum disorders

31 March 2020

1 reference

Model of autism: increased ratio of excitation/inhibition in key neural systems

31 March 2020

1 reference

Excess of high frequency electroencephalogram oscillations in boys with autism

31 March 2020

1 reference

The neural basis of addiction: a pathology of motivation and choice

31 March 2020

1 reference

Addiction and schizophrenia

31 March 2020

1 reference

Quality of life in schizophrenia: contributions of anxiety and depression

31 March 2020

1 reference

CCK, schizophrenia, and anxiety. CCK-B antagonists inhibit the activity of brain dopamine neurons

31 March 2020

1 reference

Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa

31 March 2020

1 reference

Optogenetic approaches to restoring visual function in retinitis pigmentosa.

31 March 2020

1 reference

Active expiration induced by excitation of ventral medulla in adult anesthetized rats

31 March 2020

1 reference

Astrocytes control breathing through pH-dependent release of ATP

31 March 2020

1 reference

Functional architecture of basal ganglia circuits: neural substrates of parallel processing

31 March 2020

1 reference

A computational model of action selection in the basal ganglia. I. A new functional anatomy.

31 March 2020

1 reference

Behavioural assessment of mice lacking D1A dopamine receptors

31 March 2020

1 reference

Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases

31 March 2020

1 reference

Diagnostic criteria for Parkinson disease

31 March 2020

1 reference

Deep brain stimulation for Parkinson’s disease

31 March 2020

1 reference

A randomized trial of deep-brain stimulation for Parkinson's disease

31 March 2020

1 reference

Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease.

31 March 2020

1 reference

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

31 March 2020

1 reference

Functional identification of an aggression locus in the mouse hypothalamus

31 March 2020

1 reference

Optogenetics: background and concepts for neurosurgery

31 March 2020

1 reference

Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain

31 March 2020

1 reference

The dawning of primate optogenetics

31 March 2020

1 reference

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

31 March 2020

1 reference

Ultra light-sensitive and fast neuronal activation with the Ca²+-permeable channelrhodopsin CatCh.

31 March 2020

1 reference

Crystal structure of the channelrhodopsin light-gated cation channel

31 March 2020

1 reference

Contextual fear conditioning, conjunctive representations, pattern completion, and the hippocampus.

31 March 2020

1 reference

12 December 2020

Definitions of antidepressant treatment response, remission, nonresponse, partial response, and other relevant outcomes: a focus on treatment-resistant depression

1 reference

12 December 2020

Benzodiazepines: use, abuse, and consequences

1 reference

12 December 2020

Anxiety disorders: clinical presentation and epidemiology.

1 reference

12 December 2020

Prosthetic systems for therapeutic optical activation and silencing of genetically-targeted neurons

1 reference

12 December 2020

Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits

1 reference

12 December 2020

The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey

1 reference

12 December 2020

Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear

1 reference

12 December 2020

Psychobiologic mechanisms of posttraumatic stress disorder

1 reference

12 December 2020

Microcircuitry of the direct and indirect pathways of the basal ganglia

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRN3171

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

Dimensions Publication ID

11 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

PubMed publication ID

22430017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json