Endometrial carcinoma: molecular alterations involved in tumor development and progression (Q37994980)

26 August 2017

Endometrial carcinoma: molecular alterations involved in tumor development and progression (English)

1 reference

26 August 2017

endometrial carcinoma

1 reference

G Moreno-Bueno

2

0 references

author name string

A Yeramian

1

1 reference

26 August 2017

X Dolcet

3

1 reference

26 August 2017

L Catasus

4

1 reference

26 August 2017

M Abal

5

1 reference

26 August 2017

E Colas

6

1 reference

26 August 2017

J Reventos

7

1 reference

26 August 2017

J Palacios

8

1 reference

26 August 2017

J Prat

9

1 reference

26 August 2017

X Matias-Guiu

10

1 reference

26 August 2017

language of work or name

English

0 references

publication date

19 March 2012

1 reference

26 August 2017

1 reference

26 August 2017

32

1 reference

26 August 2017

403-413

1 reference

26 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2012.76

26 August 2017

0 references

cites work

Two pathogenetic types of endometrial carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Molecular pathology of endometrial hyperplasia and carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Endometrial carcinoma: pathology and genetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Microsatellite instability in sporadic endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Deletion mapping on chromosome 10q25-q26 in human endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Essential role for nuclear PTEN in maintaining chromosomal integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

PIK3CA gene mutations in endometrial carcinoma: correlation with PTEN and K-RAS alterations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Concomitant PI3K-AKT and p53 alterations in endometrial carcinomas are associated with poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Molecular alterations of EGFR and PIK3CA in uterine serous carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Expression profiling of 22 genes involved in the PI3K-AKT pathway identifies two subgroups of high-grade endometrial carcinomas with different molecular alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Promoter hypermethylation and reduced expression of RASSF1A are frequent molecular alterations of endometrial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Promoter hypermethylation and expression of sprouty 2 in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Drug-sensitive FGFR2 mutations in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Mutations of the beta-catenin gene in endometrial carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Abnormalities of the APC/beta-catenin pathway in endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

p53 in endometrial cancer and its putative precursors: evidence for diverse pathways of tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Molecular alterations in uterine serous carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Microarray analysis of endometrial carcinomas and mixed mullerian tumors reveals distinct gene expression profiles associated with different histologic types of uterine cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Distinctive gene expression profiles by cDNA microarrays in endometrioid and serous carcinomas of the endometrium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

cDNA microarray analysis and immunohistochemistry reveal a distinct molecular phenotype in serous endometrial cancer compared to endometrioid endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Molecular classification of human endometrial cancer based on gene expression profiles from specialized microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Gene expression profiling of endometrial adenocarcinomas reveals increased apolipoprotein E expression in poorly differentiated tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

A differential gene expression profile reveals overexpression of RUNX1/AML1 in invasive endometrioid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Uterine carcinosarcomas (malignant mixed Mullerian tumors) are metaplastic carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Epithelial to mesenchymal transition in early stage endometrioid endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

ETV5 transcription factor is overexpressed in ovarian cancer and regulates cell adhesion in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Subtractive proteomic approach to the endometrial carcinoma invasion front.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

KSR1 is overexpressed in endometrial carcinoma and regulates proliferation and TRAIL-induced apoptosis by modulating FLIP levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

The multikinase inhibitor Sorafenib induces apoptosis and sensitises endometrial cancer cells to TRAIL by different mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Proteasome inhibitors induce death but activate NF-kappaB on endometrial carcinoma cell lines and primary culture explants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Aberrations in the progesterone receptor gene and the risk of recurrent endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

TP53 overexpression in recurrent endometrial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

APC, beta-catenin, and E-cadherin and the development of recurrent endometrial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Immunohistochemical features of post-radiation vaginal recurrences of endometrioid carcinomas of the endometrium: role for proteins involved in resistance to apoptosis and hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Low Frequency of BRAF Mutations in Endometrial and in Cervical Carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

FGFR2 alterations in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Microsatellite instability in endometrial carcinomas: frequent replication errors in tumors of early onset and/or of poorly differentiated type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Microsatellite instability in endometrial carcinomas: clinicopathologic correlations in a series of 42 cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

PTEN mutations in endometrial carcinomas: a molecular and clinicopathologic analysis of 38 cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

PIK3CA mutations in the kinase domain (exon 20) of uterine endometrial adenocarcinomas are associated with adverse prognostic parameters

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

K-ras mutations in endometrial carcinomas with microsatellite instability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

CTNNB1 mutations and beta-catenin expression in endometrial carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Loss of heterozygosity in usual and special variant carcinomas of the endometrium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Histologic type, organ of origin, and Wnt pathway status: effect on gene expression in ovarian and uterine carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Gene expression profiling of microsatellite unstable and microsatellite stable endometrial cancers indicates distinct pathways of aberrant signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Endometrial carcinomas with ambiguous features.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Endometrial and ovarian carcinomas with undifferentiated components: clinically aggressive and frequently underrecognized neoplasms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Pathologic and molecular features of uterine carcinosarcomas.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Pathology of the endometrium. Introduction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

Defective mismatch repair and the development of recurrent endometrial carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.76

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.76

1 reference

Dimensions Publication ID

26 August 2017

1008051020

0 references

OpenCitations bibliographic resource ID

0 references

1 reference