Off-target cannabinoid effects mediated by GPR55. (Q37995375)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433274%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Off-target cannabinoid effects mediated by GPR55 (English)

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26 January 2020

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Christopher M Henstridge

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433274%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Christopher M Henstridge

series ordinal

1

1 reference

26 August 2017

16 March 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433274%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433274%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

89

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433274%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

3-4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433274%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

179-187

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In silico patent searching reveals a new cannabinoid receptor

26 January 2020

cites work

1 reference

The orphan receptor GPR55 is a novel cannabinoid receptor

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GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity?

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Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55.

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The enigmatic pharmacology of GPR55

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Pharmacological characterization of GPR55, a putative cannabinoid receptor

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Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

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Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands

21 January 2018

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Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55

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A lipid pathway for ligand binding is necessary for a cannabinoid G protein-coupled receptor

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Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist

21 January 2018

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The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

21 January 2018

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Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

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GPR55 ligands promote receptor coupling to multiple signalling pathways

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Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay

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Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids

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The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment

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Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes

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Novel cannabinoid receptors

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Cannabinoids modulate neuronal firing in the rat basolateral amygdala: evidence for CB1- and non-CB1-mediated actions

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Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus.

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Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition.

21 January 2018

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Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.

21 January 2018

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Differential changes in GPR55 during microglial cell activation

21 January 2018

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GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

21 January 2018

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Wiring and firing neuronal networks: endocannabinoids take center stage

21 January 2018

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Hardwiring the brain: endocannabinoids shape neuronal connectivity

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Lysophosphatidylinositol causes neurite retraction via GPR55, G13 and RhoA in PC12 cells

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Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections

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Differential effects of lysophospholipids on exocytosis in rat PC12 cells

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The pharmacology of cannabinoid receptors and their ligands: an overview

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Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors

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Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor

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Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery.

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Mesenteric vasodilation mediated by endothelial anandamide receptors

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The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects

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N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

21 January 2018

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Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries.

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Production and physiological actions of anandamide in the vasculature of the rat kidney.

21 January 2018

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Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

21 January 2018

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Is lipid signaling through cannabinoid 2 receptors part of a protective system?

21 January 2018

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Cannabinoids and the immune system: an overview

21 January 2018

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Endogenous cannabinoids and neutrophil chemotaxis.

21 January 2018

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GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

21 January 2018

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The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

21 January 2018

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The endocannabinoid system and pain

21 January 2018

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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

21 January 2018

1 reference

Multiple actions of anandamide on neonatal rat cultured sensory neurones

21 January 2018

1 reference

Rimonabant, a cannabinoid CB1 receptor antagonist, attenuates mechanical allodynia and counteracts oxidative stress and nerve growth factor deficit in diabetic mice

21 January 2018

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Effect of the cannabinoid CB1 receptor antagonist, SR141716, on nociceptive response and nerve demyelination in rodents with chronic constriction injury of the sciatic nerve

21 January 2018

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The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55.

21 January 2018

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Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.

21 January 2018

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Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer

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Loss of cannabinoid receptor 1 accelerates intestinal tumor growth

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Cannabinoids: potential anticancer agents

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Cannabinoids for cancer treatment: progress and promise

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Cannabinoids and gliomas.

21 January 2018

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The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK.

21 January 2018

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A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells.

21 January 2018

1 reference

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation

21 January 2018

1 reference

Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor

21 January 2018

1 reference

Elevated levels and mitogenic activity of lysophosphatidylinositol in k-ras-transformed epithelial cells.

21 January 2018

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Release of the mitogen lysophosphatidylinositol from H-Ras-transformed fibroblasts; a possible mechanism of autocrine control of cell proliferation.

21 January 2018

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Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes

21 January 2018

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Functional polymorphism in the GPR55 gene is associated with anorexia nervosa.

21 January 2018

1 reference

The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity

21 January 2018

1 reference

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.

21 January 2018

1 reference

A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans.

21 January 2018

1 reference