The tangled web of non-canonical Wnt signalling in neural migration (Q37997883)

26 August 2017

The tangled web of non-canonical Wnt signalling in neural migration (English)

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26 August 2017

Charlotte E J Clark

1

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PubMed ID

22456117

26 August 2017

C Cathrin Nourse

series ordinal

2

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PubMed ID

22456117

26 August 2017

Helen M Cooper

series ordinal

3

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26 August 2017

27 March 2012

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26 August 2017

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26 August 2017

20

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26 August 2017

3

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26 August 2017

202-220

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What sponges can tell us about the evolution of developmental processes.

26 August 2017

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Structure and expression of conserved Wnt pathway components in the demosponge Amphimedon queenslandica.

21 January 2018

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Towards an integrated view of Wnt signaling in development

21 January 2018

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Wnt signaling during synaptic development and plasticity

21 January 2018

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Wnt signaling and neurite outgrowth: insights and questions

21 January 2018

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The plane facts of PCP in the CNS

21 January 2018

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Wnt signaling in neural circuit assembly

21 January 2018

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Migration of neuronal cells along the anterior-posterior body axis of C. elegans: Wnts are in control

21 January 2018

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

21 January 2018

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The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein

21 January 2018

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A frizzled homolog functions in a vertebrate Wnt signaling pathway

21 January 2018

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The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling

21 January 2018

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The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling

21 January 2018

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Structure-function analysis of Frizzleds

21 January 2018

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Dishevelled: The hub of Wnt signaling

21 January 2018

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Wnt/beta-catenin signaling: new (and old) players and new insights

21 January 2018

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A quest for the mechanism regulating global planar cell polarity of tissues

21 January 2018

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Tissue/planar cell polarity in vertebrates: new insights and new questions

21 January 2018

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Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2

21 January 2018

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Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

21 January 2018

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Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance

21 January 2018

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Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

21 January 2018

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Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

21 January 2018

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Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

21 January 2018

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The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

21 January 2018

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Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus

21 January 2018

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Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.

21 January 2018

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Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

21 January 2018

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Induction of filopodia by direct local elevation of intracellular calcium ion concentration

21 January 2018

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Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

21 January 2018

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Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2+ signaling.

21 January 2018

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Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development

21 January 2018

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Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

21 January 2018

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The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cells

21 January 2018

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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

21 January 2018

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The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

21 January 2018

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Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration

21 January 2018

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The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src

21 January 2018

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Homodimerization of Ror2 tyrosine kinase receptor induces 14-3-3(beta) phosphorylation and promotes osteoblast differentiation and bone formation

21 January 2018

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Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase

21 January 2018

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Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development

21 January 2018

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Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases

21 January 2018

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Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A.

21 January 2018

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JNK phosphorylates paxillin and regulates cell migration

21 January 2018

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Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells

21 January 2018

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Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling

21 January 2018

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Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

21 January 2018

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Opposing Wnt pathways orient cell polarity during organogenesis

21 January 2018

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Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization

21 January 2018

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Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase

21 January 2018

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Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.

21 January 2018

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The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon

21 January 2018

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Cell-type specific modular regulation of derailed in the Drosophila nervous system.

21 January 2018

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Wnt-mediated axon guidance via the Drosophila Derailed receptor

21 January 2018

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The Drosophila learning and memory gene linotte encodes a putative receptor tyrosine kinase homologous to the human RYK gene product.

21 January 2018

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Derailed regulates development of the Drosophila neuromuscular junction

21 January 2018

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The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum

21 January 2018

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Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms

21 January 2018

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Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract

21 January 2018

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Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

21 January 2018

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Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements

21 January 2018

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Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis

21 January 2018

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Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain

21 January 2018

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The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development.

21 January 2018

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21 January 2018

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Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk

21 January 2018

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Genomic structure and expression of the mouse growth factor receptor related to tyrosine kinases (Ryk).

21 January 2018

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RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs

21 January 2018

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Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family

21 January 2018

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Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system

21 January 2018

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21 January 2018

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Wnt/calcium signaling mediates axon growth and guidance in the developing corpus callosum

21 January 2018

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Neurulation in the cranial region--normal and abnormal

21 January 2018

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Neural tube closure and neural tube defects: studies in animal models reveal known knowns and known unknowns

21 January 2018

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Mechanisms of convergence and extension by cell intercalation

21 January 2018

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Monopolar protrusive activity: a new morphogenic cell behavior in the neural plate dependent on vertical interactions with the mesoderm in Xenopus

21 January 2018

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The presumptive floor plate (notoplate) induces behaviors associated with convergent extension in medial but not lateral neural plate cells of Xenopus

21 January 2018

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Planar cell polarity, ciliogenesis and neural tube defects

21 January 2018

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Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity.

21 January 2018

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Dishevelled controls cell polarity during Xenopus gastrulation

21 January 2018

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Shaping the vertebrate body plan by polarized embryonic cell movements

21 January 2018

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The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation

21 January 2018

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Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility

21 January 2018

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Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation

21 January 2018

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Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway

21 January 2018

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Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure

21 January 2018

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Neural tube closure requires Dishevelled-dependent convergent extension of the midline

21 January 2018

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Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

21 January 2018

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Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

21 January 2018

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Mutations in VANGL1 associated with neural-tube defects

21 January 2018

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VANGL2 mutations in human cranial neural-tube defects

21 January 2018

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Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

21 January 2018

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Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development

21 January 2018

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Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling.

21 January 2018

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Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

21 January 2018

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Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

21 January 2018

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The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

21 January 2018

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Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway

21 January 2018

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Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

21 January 2018

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Wnt5a regulates distinct signalling pathways by binding to Frizzled2

21 January 2018

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Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway

21 January 2018

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Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

21 January 2018

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Wnt5a functions in planar cell polarity regulation in mice

21 January 2018

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Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

21 January 2018

1 reference

The cell biology of neuronal navigation

21 January 2018

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Microtubule assembly, organization and dynamics in axons and dendrites

21 January 2018

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Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance

21 January 2018

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Wnt-Ror signaling to SIA and SIB neurons directs anterior axon guidance and nerve ring placement in C. elegans

21 January 2018

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Midline axon guidance and human genetic disorders

21 January 2018

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Mechanisms and molecules of neuronal wiring: a primer

21 January 2018

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The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

21 January 2018

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Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

21 January 2018

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Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

21 January 2018

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Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling

21 January 2018

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Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance.

21 January 2018

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The PAR proteins: fundamental players in animal cell polarization

21 January 2018

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Parsing the polarity code

21 January 2018

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Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity.

21 January 2018

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NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC

21 January 2018

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Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development.

21 January 2018

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PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

21 January 2018

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Regulation of Lethal giant larvae by Dishevelled

21 January 2018

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The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

21 January 2018

1 reference

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

21 January 2018

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Dishevelled promotes axon differentiation by regulating atypical protein kinase C.

21 January 2018

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Molecular mechanisms of axon guidance in the developing corticospinal tract.

21 January 2018

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Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity.

21 January 2018

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Axonal pathfinding mechanisms at the cortical midline and in the development of the corpus callosum.

21 January 2018

1 reference

Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000332153

1 reference

26 August 2017

1 reference

PubMed ID

22456117