Interferon signatures in immune disorders and disease (Q38001532)

26 August 2017

Interferon signatures in immune disorders and disease (English)

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26 August 2017

1

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26 August 2017

10 April 2012

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Immunology & Cell Biology

26 August 2017

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26 August 2017

90

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26 August 2017

5

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26 August 2017

520-527

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Alpha interferon treatment may prevent hepatocellular carcinoma in HCV-related liver cirrhosis.

26 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon in oncological practice: review of interferon biology, clinical applications, and toxicities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Characterization of the type I interferon locus and identification of novel genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Evolutionary genetic dissection of human interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Induction of type I IFNs by intracellular DNA-sensing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Role of Stat5 in type I interferon-signaling and transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

The interferons and their receptors--distribution and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon alpha /beta promotes cell survival by activating nuclear factor kappa B through phosphatidylinositol 3-kinase and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

System-level comparison of protein-protein interactions between viruses and the human type I interferon system network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Global changes in STAT target selection and transcription regulation upon interferon treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

A diverse range of gene products are effectors of the type I interferon antiviral response

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2012.12

INTERFEROME: the database of interferon regulated genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2012.12

Systems biology of interferon responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Modulation of alpha interferon anti-hepatitis C virus activity by ISG15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Protein ISGylation modulates the JAK-STAT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: characteriza

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Large-scale monitoring of host cell gene expression during HIV-1 infection using cDNA microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon-alpha produces significant decreases in HIV load

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Phase I trial of interferon alfa-n3 in early-stage human immunodeficiency virus type 1 disease: evidence for drug safety, tolerance, and antiviral activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Peginterferon Alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Pegylated interferon alfa-2b vs standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected patients: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Genomic response to interferon-alpha in chimpanzees: implications of rapid downregulation for hepatitis C kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Detection of a novel unglycosylated form of hepatitis C virus E2 envelope protein that is located in the cytosol and interacts with PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon signaling and treatment outcome in chronic hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

ISG15, a ubiquitin-like interferon-stimulated gene, promotes hepatitis C virus production in vitro: implications for chronic infection and response to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Conjugation of the 15-kDa interferon-induced ubiquitin homolog is distinct from that of ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Silencing of USP18 potentiates the antiviral activity of interferon against hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Knockdown of USP18 increases α 2a interferon signaling and induction of interferon-stimulating genes but does not increase antiviral activity in Huh7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Inhibition of human immunodeficiency virus type 1 and vaccinia virus infection by a dominant negative factor of the interferon regulatory factor family expressed in monocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Exogenous HIV-1 Vpr disrupts IFN-alpha response by plasmacytoid dendritic cells (pDCs) and subsequent pDC/NK interplay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Induction of autoreactive B cells allows priming of autoreactive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Abnormal T cell signal transduction in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

TLR7 ligands induce higher IFN-alpha production in females.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Role of type I interferons in the activation of autoreactive B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Type I interferon in systemic lupus erythematosus and other autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Natural killer T cells in families of patients with systemic lupus erythematosus: their possible role in regulation of IGG production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Toll-like receptors as interferon-regulated genes and their role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Plasma titers of antibodies against Epstein-Barr virus BZLF1 and risk of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Administration of imiquimod, an interferon inducer, in asymptomatic human immunodeficiency virus-infected persons to determine safety and biologic response modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Low plasma concentrations of interleukin-10 in severe malarial anaemia compared with cerebral and uncomplicated malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Low interleukin-12 activity in severe Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Evidence that interferon-gamma plays a protective role during cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Interferon-alpha receptor-1 (IFNAR1) variants are associated with protection against cerebral malaria in the Gambia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Beta interferon suppresses the development of experimental cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Innate immune recognition of Yersinia pseudotuberculosis type III secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Induction of type I interferons by bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Expression of the nitric oxide synthase 2 gene is not essential for early control of Mycobacterium tuberculosis in the murine lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Curating the innate immunity interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

The Innate Immune Database (IIDB)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

Type I interferons and autoimmunity: lessons from the clinic and from IRF-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

Alpha interferon-induced antiretroviral activities: restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

Nucleosomes are major T and B cell autoantigens in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

Primary infection with the Epstein-Barr virus and risk of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

A subtype of multiple sclerosis defined by an activated immune defense program

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

The effect of interferon-beta on blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2012.12

7 January 2021

Identifiers

DOI

10.1038/ICB.2012.12

1 reference

26 August 2017

1 reference

PubMed ID

22491066