Effects of hypoxia and HIFs on cancer metabolism (Q38005965)

26 August 2017

Effects of hypoxia and HIFs on cancer metabolism (English)

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26 August 2017

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Vera Mucaj

1

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26 August 2017

Jessica E S Shay

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2

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26 August 2017

M Celeste Simon

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3

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26 August 2017

27 April 2012

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International Journal of Hematology

26 August 2017

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26 August 2017

95

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26 August 2017

464-470

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26 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s12185-012-1070-5

26 August 2017

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cites work

The impact of O2 availability on human cancer

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Hypoxia regulates macrophage functions in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Hypoxia-inducible factors and the response to hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Biology of hypoxia-inducible factor-2alpha in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Targeting the Warburg effect in hematological malignancies: from PET to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-1: upstream and downstream of cancer metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

How does PKMζ maintain long-term memory?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

FLT3 as a therapeutic target in AML: still challenging after all these years

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1α-mediated down-regulation of CXCL12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Regulation of energy metabolism in macrophages during hypoxia. Roles of fructose 2,6-bisphosphate and ribose 1,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

HIF-1alpha is essential for myeloid cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12185-012-1070-5

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

21 January 2018

1 reference

12 December 2020

Kidney cancer: now available in a new flavor

1 reference

12 December 2020

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

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12 December 2020

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

1 reference

12 December 2020

Good neighbours in the tumour stroma reduce oxidative stress

1 reference

12 December 2020

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

1 reference

12 December 2020

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

1 reference

12 December 2020

10.1007/S12185-012-1070-5

Identifiers

DOI

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Dimensions Publication ID

26 August 2017

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