ApoE genotype: from geographic distribution to function and responsiveness to dietary factors (Q38008109)

26 August 2017

ApoE genotype: from geographic distribution to function and responsiveness to dietary factors (English)

1 reference

26 August 2017

Sarah Egert

1

1 reference

PubMed ID

22564824

26 August 2017

Gerald Rimbach

series ordinal

2

1 reference

PubMed ID

22564824

26 August 2017

Patricia Huebbe

series ordinal

3

1 reference

26 August 2017

8 May 2012

1 reference

Proceedings of the Nutrition Society

26 August 2017

1 reference

26 August 2017

71

1 reference

26 August 2017

3

1 reference

26 August 2017

410-424

1 reference

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

26 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Abnormal in vivo metabolism of apolipoprotein E4 in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Isoprotein specificity in the hepatic uptake of apolipoprotein E and the pathogenesis of familial dysbetalipoproteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E: from lipid transport to neurobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

apoE4 allele and the natural history of cardiovascular risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Gene polymorphisms affecting HDL-cholesterol levels in the normolipidemic population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Associations between apolipoprotein E genotype and circulating F2-isoprostane levels in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Saturated fat intake and alcohol consumption modulate the association between the APOE polymorphism and risk of future coronary heart disease: a nested case-control study in the Spanish EPIC cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Interactions between age and apoE genotype on fasting and postprandial triglycerides levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

ESR1 and APOE gene polymorphisms, serum lipids, and hormonal replacement therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Association of apolipoprotein E genotypes with lipid levels and coronary risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E polymorphism, age and coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Contribution of apolipoprotein E genotype and docosahexaenoic acid to the LDL-cholesterol response to fish oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Genetic associations with human longevity at the APOE and ACE loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

ApoE polymorphisms and diarrheal outcomes in Brazilian shanty town children

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E-epsilon 4 protects against severe liver disease caused by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein 3 allele is associated with persistent hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Herpes simplex virus type 1, apolipoprotein E, and cholesterol: a dangerous liaison in Alzheimer's disease and other disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Herpes simplex virus type 1 in brain and risk of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Heritability of C-reactive protein and association with apolipoprotein E genotypes in Japanese Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E genotype in dyslipidemic patients and response of blood lipids and inflammatory markers to alpha-linolenic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

ApoE plasma levels and risk of cardiovascular mortality in old age

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Alpha-linolenic acid: is it essential to cardiovascular health?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Dietary alpha-linolenic acid and health-related outcomes: a metabolic perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Impact of n-3 fatty acids on endothelial function: results from human interventions studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Long-chain n-3 polyunsaturated fatty acids: new insights into mechanisms relating to inflammation and coronary heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Cardiovascular effects of marine omega-3 fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Fish, long-chain omega-3 polyunsaturated fatty acids and prevention of cardiovascular disease--eat fish or take fish oil supplement?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk: a literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

ApoE polymorphism is associated with C-reactive protein in low-HDL family members and in normolipidemic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Inflammatory marker expression and its implication in Korean ischemic stroke patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

C-reactive protein and rate of dementia in carriers and non carriers of Apolipoprotein APOE4 genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Association of high sensitive C-reactive protein with apolipoprotein E polymorphism in children and young adults: the Cardiovascular Risk in Young Finns Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E genotype and sex influence C-reactive protein levels regardless of exercise training status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

High levels of serum C-reactive protein are associated with greater risk of all-cause mortality, but not dementia, in the oldest-old: results from The 90+ Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

APOE polymorphism and its effect on plasma C-reactive protein levels in a large general population sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Effect of apoE genotype and dietary quercetin on blood lipids and TNF-alpha levels in apoE3 and apoE4 targeted gene replacement mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Antihypertensive effects of the flavonoid quercetin

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Quercetin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysm

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Impact of apolipoprotein E genotype and dietary quercetin on paraoxonase 1 status in apoE3 and apoE4 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

APOE genotypes and dyslipidemias in a sample of the Portuguese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

ApoE4-dependent Abeta-mediated neurodegeneration is associated with inflammatory activation in the hippocampus but not the septum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

APOE genotype-specific differences in the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E4 enhances brain inflammation by modulation of the NF-kappaB signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

APOE distribution in world populations with new data from India and the UK

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Effects of apoE genotype on macrophage inflammation and heme oxygenase-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Nrf2-dependent gene expression is affected by the proatherogenic apoE4 genotype-studies in targeted gene replacement mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Fruit polyphenols and CVD risk: a review of human intervention studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Flavonols, flavones, flavanones, and human health: epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Vitamin D and disease prevention with special reference to cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Implications of apolipoprotein E genotype on inflammation and vitamin E status

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Alpha-tocopherol transport in the lung is affected by the apoE genotype--studies in transgenic apoE3 and apoE4 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a 'thrifty' allele?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Physiological factors influencing vitamin E biokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Influence of apolipoprotein E polymorphism on plasma vitamin A and vitamin E levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Arginine residues at codons 112 and 158 in the apolipoprotein E gene correspond to the ancestral state in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Evolution in health and medicine Sackler colloquium: Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

The significant increase in cardiovascular disease risk in APOEepsilon4 carriers is evident only in men who smoke: potential relationship between reduced antioxidant status and ApoE4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Diverse roles for the LDL receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Relationship between oxidative stress and apoE phenotype in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Differential effects of apolipoprotein E3 and E4 on markers of oxidative status in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E isoform mediated regulation of nitric oxide release

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Apolipoprotein E genotype and statins affect CRP levels through independent and different mechanisms: AGES-Reykjavik Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

Genetic predisposition in patients undergoing cardiopulmonary bypass surgery is associated with an increase of inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Electrophoretic analysis of oxidative modification of apolipoprotein E in very low density lipoprotein from fresh human plasma

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Differential distribution of apolipoprotein E isoforms in human plasma lipoproteins

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Presence of apolipoprotein E epsilon4 allele predisposes to early onset of primary Sjogren's syndrome

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DC.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Quercetin reduces blood pressure in hypertensive subjects

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Vitamin D status and health correlates among German adults

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Structural variation manipulates the differential oxidative susceptibility and conformational stability of apolipoprotein E isoforms

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Apolipoprotein E genotype and circulating interleukin-10 levels in patients with stable and unstable coronary artery disease

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Does the geographical gradient of ApoE4 allele exist in China? A systemic comparison among multiple Chinese populations

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Apolipoprotein E polymorphism and atherosclerosis

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Alcohol drinking determines the effect of the APOE locus on LDL-cholesterol concentrations in men: the Framingham Offspring Study

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

APO E gene and gene-environment effects on plasma lipoprotein-lipid levels

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Modest protective effects of isoflavones from a red clover-derived dietary supplement on cardiovascular disease risk factors in perimenopausal women, and evidence of an interaction with ApoE genotype in 49-65 year-old women.

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Apolipoprotein E polymorphism and C-reactive protein in dyslipidemic middle-aged men

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele

1 reference

https://api.crossref.org/works/10.1017%2FS0029665112000249

7 January 2021

10.1017/S0029665112000249

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22564824