Clinical perspective: statins and the liver--harmful or helpful? (Q38009719)

26 August 2017

Clinical perspective: statins and the liver--harmful or helpful? (English)

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26 August 2017

James H Lewis

1

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26 August 2017

12 May 2012

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Digestive Diseases and Sciences

26 August 2017

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26 August 2017

57

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26 August 2017

7

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26 August 2017

1754-1763

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https://scigraph.springernature.com/pub.10.1007/s10620-012-2207-3

26 August 2017

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21 January 2018

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21 January 2018

The liver and lovastatin

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Patients with elevated baseline liver enzymes do not have higher frequency of hepatotoxicity from lovastatin than those with normal baseline liver enzymes.

21 January 2018

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Statins in liver disease: a molehill, an iceberg, or neither?

21 January 2018

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The myth of statin-induced hepatotoxicity

21 January 2018

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Liver tests are irrelevant when prescribing statins

21 January 2018

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Drug-induced liver injury associated with statins

21 January 2018

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21 January 2018

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Liver function tests and statins

21 January 2018

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Statins in the treatment of dyslipidemia in the presence of elevated liver aminotransferase levels: a therapeutic dilemma

21 January 2018

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Use of statins in patients with liver disease.

21 January 2018

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3-hydroxyl-3-methylglutaryl coenzyme A reductase inhibitor use in chronic liver disease: a therapeutic controversy

21 January 2018

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Defining patient risks from expanded preventive therapies

21 January 2018

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Hepatic effects of lovastatin exposure in patients with liver disease: a retrospective cohort study

21 January 2018

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Statins and hepatotoxicity: focus on patients with fatty liver

21 January 2018

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Fulminant drug-induced hepatic failure leading to death or liver transplantation in Sweden

21 January 2018

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Suspected drug-induced liver fatalities reported to the WHO database

21 January 2018

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Biochemical changes and morphological alterations of the liver in guinea-pigs after administration of simvastatin (HMG CoA reductase-inhibitor).

21 January 2018

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Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity?

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

21 January 2018

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Evaluation of cases of severe statin-related transaminitis within a large health maintenance organization

21 January 2018

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Outcome of liver transplantation for drug-induced acute liver failure in the United States: analysis of the United Network for Organ Sharing database.

21 January 2018

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Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury

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21 January 2018

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21 January 2018

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Important elements for the diagnosis of drug-induced liver injury

21 January 2018

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The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury.

21 January 2018

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Causality assessment of drug-induced hepatotoxicity: promises and pitfalls

21 January 2018

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Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method

21 January 2018

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Accuracy of hepatic adverse drug reaction reporting in one English health region

21 January 2018

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21 January 2018

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Marked elevation in serum transaminases: an atypical presentation of choledocholithiasis

21 January 2018

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Hypoxic hepatitis: clinical and hemodynamic study in 142 consecutive cases

21 January 2018

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Hepatic findings in long-term clinical trials of ximelagatran

21 January 2018

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Incidence of statin hepatotoxicity in patients with hepatitis C.

21 January 2018

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Effectiveness and hepatotoxicity of statins in men seropositive for hepatitis C virus

21 January 2018

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Statin therapy and serum transaminases among a cohort of HCV-infected veterans

21 January 2018

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Statins improve ALT values in chronic hepatitis C patients with abnormal values

21 January 2018

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Serum cholesterol and statin use predict virological response to peginterferon and ribavirin therapy

21 January 2018

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Correlation between beta-lipoprotein levels and outcome of hepatitis C treatment

21 January 2018

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The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.

21 January 2018

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Targeting lipid metabolism in the treatment of hepatitis C virus infection

21 January 2018

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Different anti-HCV profiles of statins and their potential for combination therapy with interferon

21 January 2018

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21 January 2018

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Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development

21 January 2018

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Does fluvastatin favour HCV replication in vivo? A pilot study on HIV-HCV coinfected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Fluvastatin inhibits hepatitis C replication in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Simvastatin potentiates the anti-hepatitis B virus activity of FDA-approved nucleoside analogue inhibitors in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

A pilot study using simvastatin in the treatment of nonalcoholic steatohepatitis: A randomized placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial

21 January 2018

1 reference

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Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Lovastatin interacts with natural products to influence cultured hepatocarcinoma cell (hep-g2) growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Simvastatin protects against cholestasis-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Fluvastatin reduced liver injury in rat model of extrahepatic cholestasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Addition of simvastatin to cold storage solution prevents endothelial dysfunction in explanted rat livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Liver enzyme monitoring in patients treated with troglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Is there value in liver function test and creatine phosphokinase monitoring with statin use?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Compliance to recommended liver function monitoring in patients on statin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Final conclusions and recommendations of the National Lipid Association Statin Safety Assessment Task Force.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Fluvastatin and hepatic reactions: a signal from spontaneous reporting in Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-012-2207-3

Yes! Statins can be given to liver patients

21 January 2018

1 reference

12 December 2020

Statins and elevated liver tests: what's the fuss?

1 reference

12 December 2020

Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial

1 reference

12 December 2020

An assessment of statin safety by hepatologists

1 reference

12 December 2020

Drug-induced liver injury in a Swedish University hospital out-patient hepatology clinic

1 reference

12 December 2020

FDA adverse event reports on statin-associated rhabdomyolysis

1 reference

12 December 2020

Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period

1 reference

12 December 2020

Toxicity of the HMG-coenzyme A reductase inhibitor, lovastatin, to rabbits

1 reference

12 December 2020

10.1007/S10620-012-2207-3

Identifiers

DOI

1 reference

PubMed ID

22581301

Dimensions Publication ID

26 August 2017

0 references

1 reference

PubMed ID

22581301