Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation (Q28285842)

GOA release 2020-03-11

author

Kari Alitalo

21

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Seppo Ylä-Herttuala

16

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Tuomas Tammela

1

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Christer Betsholtz

20

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Catarina Freitas

Catarina Freitas

11

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Mats Hellström

Mats Hellström

8

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Pirjo Laakkonen

Pirjo Laakkonen

14

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Anne Eichmann

19

Anne Eichmann

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Elisabet Wallgard

3

Elisabet Wallgard

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Bronislaw Pytowski

18

Bronislaw Pytowski

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Maria Wirzenius

6

Maria Wirzenius

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Aino Murtomäki

4

Aino Murtomäki

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author name string

Georgia Zarkada

2

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Steven Suchting

5

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Marika Waltari

7

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Tibor Schomber

9

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Reetta Peltonen

10

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Antonio Duarte

12

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Helena Isoniemi

13

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Gerhard Christofori

15

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Masabumi Shibuya

Angiogenesis in life, disease and medicine

17

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language of work or name

English

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publication date

31 July 2008

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published in

Nature

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volume

454

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issue

7204

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page(s)

656-60

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

The biology of VEGF and its receptors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Regulation of vascular morphogenesis by Notch signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Lymphangiogenesis in development and human disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Vascular Endothelial Growth Factor Receptor 3 Is Involved in Tumor Angiogenesis and Growth

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Angiogenesis as a therapeutic target

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Lymphangiogenesis and cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Dosage-sensitive requirement for mouse Dll4 in artery development

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

VEGFR-2-specific ligand VEGF-E induces non-edematous hyper-vascularization in mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Chimeric VEGF-E(NZ7)/PlGF promotes angiogenesis via VEGFR-2 without significant enhancement of vascular permeability and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Lymphangiogenic gene therapy with minimal blood vascular side effects

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07083

7 January 2021

Identifiers

DOI

10.1038/NATURE07083

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2753973

1007540186

0 references

2753973

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference