The development of FtsZ inhibitors as potential antibacterial agents (Q38013726)

27 August 2017

title

The development of FtsZ inhibitors as potential antibacterial agents (English)

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27 August 2017

Siti Ma

1

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27 August 2017

Shutao Ma

series ordinal

2

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27 August 2017

language of work or name

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25 May 2012

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27 August 2017

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27 August 2017

volume

7

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27 August 2017

issue

7

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27 August 2017

page(s)

1161-1172

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Methicillin resistant Staphylococcus aureus in the critically ill.

27 August 2017

cites work

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Tubulin and FtsZ form a distinct family of GTPases

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Escherichia coli cell division protein FtsZ is a guanine nucleotide binding protein

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Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches

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Cell-division inhibitors: new insights for future antibiotics

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21 January 2018

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A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus

21 January 2018

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Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry

21 January 2018

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Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative?

21 January 2018

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Straight and curved conformations of FtsZ are regulated by GTP hydrolysis

21 January 2018

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Escherichia coli FtsZ polymers contain mostly GTP and have a high nucleotide turnover

21 January 2018

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GTP analogue inhibits polymerization and GTPase activity of the bacterial protein FtsZ without affecting its eukaryotic homologue tubulin

21 January 2018

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Temporal and spatial regulation in prokaryotic cell cycle progression and development

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The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke

21 January 2018

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Unique and overlapping roles for ZipA and FtsA in septal ring assembly in Escherichia coli

21 January 2018

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Glutamate-induced assembly of bacterial cell division protein FtsZ.

21 January 2018

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A malachite green colorimetric assay for protein phosphatase activity

21 January 2018

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BisANS binding to tubulin: isothermal titration calorimetry and the site-specific proteolysis reveal the GTP-induced structural stability of tubulin

21 January 2018

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Deuterium oxide promotes assembly and bundling of FtsZ protofilaments

21 January 2018

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Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling

21 January 2018

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21 January 2018

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21 January 2018

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An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

21 January 2018

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Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.

21 January 2018

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Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties

21 January 2018

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Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Antibacterial activity of leaf essential oils and their constituents from Cinnamomum osmophloeum

21 January 2018

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Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ

21 January 2018

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How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Berberine sulfate: antimicrobial activity, bioassay, and mode of action

21 January 2018

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In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis.

21 January 2018

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Berberine targets assembly of Escherichia coli cell division protein FtsZ.

21 January 2018

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Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

21 January 2018

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Synthesis of (-)-viriditoxin: a 6,6'-binaphthopyran-2-one that targets the bacterial cell division protein FtsZ.

21 January 2018

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Mode of antibacterial action of totarol, a diterpene from Podocarpus nagi.

21 January 2018

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Effects of (+)-totarol, a diterpenoid antibacterial agent, on phospholipid model membranes

21 January 2018

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The synthesis and antibacterial activity of totarol derivatives. Part 3: Modification of ring-B.

21 January 2018

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Totarol inhibits bacterial cytokinesis by perturbing the assembly dynamics of FtsZ.

21 January 2018

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Naturally occurring antiacne agents

21 January 2018

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(+)-Totarol from Chamaecyparis nootkatensis and activity against Mycobacterium tuberculosis

21 January 2018

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Synthesis of antimicrobial natural products targeting FtsZ: (+)-totarol and related totarane diterpenes

21 January 2018

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Bis-ANS as a specific inhibitor for microtubule-associated protein induced assembly of tubulin

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

FtsZ: a novel target for tuberculosis drug discovery

21 January 2018

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2-Alkoxycarbonylaminopyridines: inhibitors of Mycobacterium tuberculosis FtsZ.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

A new 2-carbamoyl pteridine that inhibits mycobacterial FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Tubulin-like protofilaments in Ca2+-induced FtsZ sheets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

GTP hydrolysis of cell division protein FtsZ: evidence that the active site is formed by the association of monomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

A 4-aminofurazan derivative-A189-inhibits assembly of bacterial cell division protein FtsZ in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Microtubules as a target for anticancer drugs

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Interaction between the C-terminal peptides of tubulin and tubulin S detected with the fluorescent probe 4',6-diamidino-2-phenylindole

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

4',6-Diamidino-2-phenylindole (DAPI) induces bundling of Escherichia coli FtsZ polymers inhibiting the GTPase activity.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Novel compound with potential of an antibacterial drug targets FtsZ protein

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

N-terminal stathmin-like peptides bind tubulin and impede microtubule assembly

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

The stathmin-derived I19L peptide interacts with FtsZ and alters its bundling

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Inhibition of septation in Bacillus subtilis by a peptide antibiotic, edeine B(1).

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Binding of neomycin-class aminoglycoside antibiotics to mutant ribosomes with alterations in the A site of 16S rRNA.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Versatility of aminoglycosides and prospects for their future

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Molecular insights into aminoglycoside action and resistance

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Sublethal concentrations of the aminoglycoside amikacin interfere with cell division without affecting chromosome dynamics

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Anti-tumour and antioxidant activity of natural curcuminoids

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Slow polymerization of Mycobacterium tuberculosis FtsZ

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Synthesis of antimicrobial natural products targeting FtsZ: (+/-)-dichamanetin and (+/-)-2' ''-hydroxy-5' '-benzylisouvarinol-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201200156

Escherichia coli cell-division gene ftsZ encodes a novel GTP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

The essential bacterial cell-division protein FtsZ is a GTPase

21 January 2018

1 reference

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Comparison of DNA fingerprinting by PFGE and PCR-RFLP of the coagulase gene to distinguish MRSA isolates

21 January 2018

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Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

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Inhibition of assembly of bacterial cell division protein FtsZ by the hydrophobic dye 5,5'-bis-(8-anilino-1-naphthalenesulfonate)

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Antimicrotubule properties of benzophenanthridine alkaloids

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Effects of tubulin assembly inhibitors on cell division in prokaryotes in vivo

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Identifiers

DOI

10.1002/CMDC.201200156

1 reference

27 August 2017

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