The development of FtsZ inhibitors as potential antibacterial agents (Q38013726)

27 August 2017

The development of FtsZ inhibitors as potential antibacterial agents (English)

1 reference

27 August 2017

Siti Ma

1

1 reference

PubMed ID

22639193

27 August 2017

Shutao Ma

series ordinal

2

1 reference

PubMed ID

22639193

27 August 2017

language of work or name

1 reference

25 May 2012

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27 August 2017

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27 August 2017

7

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27 August 2017

7

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27 August 2017

1161-1172

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Methicillin resistant Staphylococcus aureus in the critically ill.

27 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Bacterial cell division: the mechanism and its precison

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Thermosensitive Mutants of E. coli Affected in the Processes of DNA Synthesis and Cellular Division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

FtsZ ring structure associated with division in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Crystal structure of the bacterial cell-division protein FtsZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Tubulin and FtsZ form a distinct family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Escherichia coli cell division protein FtsZ is a guanine nucleotide binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Bacterial cell division: assembly, maintenance and disassembly of the Z ring

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

FtsZ in bacterial cytokinesis: cytoskeleton and force generator all in one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

FtsZ exhibits rapid movement and oscillation waves in helix-like patterns in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

21 January 2018

Cytokinesis in bacteria

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Reconstitution of contractile FtsZ rings in liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

The prokaryotic cytoskeleton: a putative target for inhibitors and antibiotics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Cell-division inhibitors: new insights for future antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Bacterial cell division and the septal ring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Polymerization of Ftsz, a bacterial homolog of tubulin. is assembly cooperative?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Straight and curved conformations of FtsZ are regulated by GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Escherichia coli FtsZ polymers contain mostly GTP and have a high nucleotide turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Rate-limiting guanosine 5'-triphosphate hydrolysis during nucleotide turnover by FtsZ, a prokaryotic tubulin homologue involved in bacterial cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

GTP analogue inhibits polymerization and GTPase activity of the bacterial protein FtsZ without affecting its eukaryotic homologue tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Temporal and spatial regulation in prokaryotic cell cycle progression and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Corey-Chaykovsky epoxidation of twisted amides: synthesis and reactivity of bridged spiro-epoxyamines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Unique and overlapping roles for ZipA and FtsA in septal ring assembly in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Glutamate-induced assembly of bacterial cell division protein FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

A malachite green colorimetric assay for protein phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

BisANS binding to tubulin: isothermal titration calorimetry and the site-specific proteolysis reveal the GTP-induced structural stability of tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Deuterium oxide promotes assembly and bundling of FtsZ protofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Ligand efficiency: a useful metric for lead selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

An inhibitor of FtsZ with potent and selective anti-staphylococcal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Antibacterial activity of leaf essential oils and their constituents from Cinnamomum osmophloeum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Berberine sulfate: antimicrobial activity, bioassay, and mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Berberine targets assembly of Escherichia coli cell division protein FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Synthesis of (-)-viriditoxin: a 6,6'-binaphthopyran-2-one that targets the bacterial cell division protein FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Mode of antibacterial action of totarol, a diterpene from Podocarpus nagi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Effects of (+)-totarol, a diterpenoid antibacterial agent, on phospholipid model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

The synthesis and antibacterial activity of totarol derivatives. Part 3: Modification of ring-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Totarol inhibits bacterial cytokinesis by perturbing the assembly dynamics of FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Naturally occurring antiacne agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

(+)-Totarol from Chamaecyparis nootkatensis and activity against Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Synthesis of antimicrobial natural products targeting FtsZ: (+)-totarol and related totarane diterpenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Bis-ANS as a specific inhibitor for microtubule-associated protein induced assembly of tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

FtsZ: a novel target for tuberculosis drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

2-Alkoxycarbonylaminopyridines: inhibitors of Mycobacterium tuberculosis FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

A new 2-carbamoyl pteridine that inhibits mycobacterial FtsZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Tubulin-like protofilaments in Ca2+-induced FtsZ sheets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

GTP hydrolysis of cell division protein FtsZ: evidence that the active site is formed by the association of monomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

A 4-aminofurazan derivative-A189-inhibits assembly of bacterial cell division protein FtsZ in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Microtubules as a target for anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Interaction between the C-terminal peptides of tubulin and tubulin S detected with the fluorescent probe 4',6-diamidino-2-phenylindole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

4',6-Diamidino-2-phenylindole (DAPI) induces bundling of Escherichia coli FtsZ polymers inhibiting the GTPase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Promoting assembly and bundling of FtsZ as a strategy to inhibit bacterial cell division: a new approach for developing novel antibacterial drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Novel compound with potential of an antibacterial drug targets FtsZ protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

N-terminal stathmin-like peptides bind tubulin and impede microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

The stathmin-derived I19L peptide interacts with FtsZ and alters its bundling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Inhibition of septation in Bacillus subtilis by a peptide antibiotic, edeine B(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Binding of neomycin-class aminoglycoside antibiotics to mutant ribosomes with alterations in the A site of 16S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Versatility of aminoglycosides and prospects for their future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Molecular insights into aminoglycoside action and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Sublethal concentrations of the aminoglycoside amikacin interfere with cell division without affecting chromosome dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Anti-tumour and antioxidant activity of natural curcuminoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Slow polymerization of Mycobacterium tuberculosis FtsZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Synthesis of antimicrobial natural products targeting FtsZ: (+/-)-dichamanetin and (+/-)-2' ''-hydroxy-5' '-benzylisouvarinol-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Escherichia coli cell-division gene ftsZ encodes a novel GTP-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

The essential bacterial cell-division protein FtsZ is a GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

Comparison of DNA fingerprinting by PFGE and PCR-RFLP of the coagulase gene to distinguish MRSA isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

THE SELECTION OF MUTANTS OF ESCHERICHIA COLI WITH IMPAIRED CELL DIVISION AT ELEVATED TEMPERATURE

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Shape deformation of ternary vesicles coupled with phase separation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Inhibition of assembly of bacterial cell division protein FtsZ by the hydrophobic dye 5,5'-bis-(8-anilino-1-naphthalenesulfonate)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Antimicrotubule properties of benzophenanthridine alkaloids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Effects of tubulin assembly inhibitors on cell division in prokaryotes in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Identification of cell cycle regulators in Mycobacterium tuberculosis by inhibition of septum formation and global transcriptional analysis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200156

7 January 2021

Identifiers

DOI

10.1002/CMDC.201200156

1 reference

27 August 2017

1 reference

PubMed ID

22639193