Adiponectin: mechanistic insights and clinical implications (Q38017897)

27 August 2017

Adiponectin: mechanistic insights and clinical implications (English)

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27 August 2017

A T Turer

1

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PubMed ID

22688349

27 August 2017

P E Scherer

series ordinal

2

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27 August 2017

12 June 2012

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27 August 2017

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27 August 2017

55

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27 August 2017

2319-2326

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27 August 2017

9

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https://scigraph.springernature.com/pub.10.1007/s00125-012-2598-x

27 August 2017

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cites work

A novel serum protein similar to C1q, produced exclusively in adipocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

AdipoQ is a novel adipose-specific gene dysregulated in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Plasma adiponectin complexes have distinct biochemical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

High-molecular-weight adiponectin and the risk of type 2 diabetes in the ARIC study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

T-cadherin is critical for adiponectin-mediated cardioprotection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin: Stability in Plasma over 36 Hours and Within-Person Variation over 1 Year

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Systemic fate of the adipocyte-derived factor adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adipose tissue mass and location affect circulating adiponectin levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin-mediated stimulation of AMP-activated protein kinase (AMPK) in pancreatic beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Expression of adiponectin receptors in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Dual action of adiponectin on insulin secretion in insulin-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Regulation of beta-cell viability and gene expression by distinct agonist fragments of adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin counteracts cytokine- and fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Plasma adiponectin levels and risk of myocardial infarction in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

The link between obesity and albuminuria: adiponectin and podocyte dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin and leptin in chronic kidney disease: causal factors or mere risk markers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Serum adiponectin complexes and cardiovascular risk in children with chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Urinary adiponectin excretion: a novel marker for vascular damage in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of Type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Role of adiponectin in human skeletal muscle bioenergetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Enhanced metabolic flexibility associated with elevated adiponectin levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Enhanced fatty acid flux triggered by adiponectin overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin receptors in human adipose tissue: effects of obesity, weight loss, and fat depots.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Autocrine action of adiponectin on human fat cells prevents the release of insulin resistance-inducing factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin differentially regulates cytokines in porcine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Molecular mechanism for adiponectin-dependent M2 macrophage polarization: link between the metabolic and innate immune activity of full-length adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin reduces lipid accumulation in macrophage foam cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Adiponectin acts in the brain to decrease body weight.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Long-term central infusion of adiponectin improves energy and glucose homeostasis by decreasing fat storage and suppressing hepatic gluconeogenesis without changing food intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2598-X

Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice

21 January 2018

1 reference

12 December 2020

Adiponectin: no longer the lone soul in the fight against insulin resistance?

1 reference

12 December 2020

Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma

1 reference

12 December 2020

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

1 reference

12 December 2020

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

1 reference

12 December 2020

Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway

1 reference

12 December 2020

Adiponectin is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction in patients presenting with chest pain

1 reference

12 December 2020

Adipokines identified as new downstream targets for adiponectin: lessons from adiponectin-overexpressing or -deficient mice

1 reference

12 December 2020

Adiponectin regulates albuminuria and podocyte function in mice

1 reference

12 December 2020

10.1007/S00125-012-2598-X

Identifiers

DOI

1 reference

PubMed ID

22688349

Dimensions Publication ID

27 August 2017

0 references

1 reference

PubMed ID

22688349