NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011. (Q38018635)

27 August 2017

title

NK-1 receptor antagonists as antitumor drugs: a survey of the literature from 2000 to 2011. (English)

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27 August 2017

3

Rafael Coveñas

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27 August 2017

Miguel Muñoz

1

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27 August 2017

Juan Martinez-Armesto

series ordinal

2

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27 August 2017

language of work or name

English

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publication date

15 June 2012

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Expert Opinion on Therapeutic Patents

27 August 2017

published in

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27 August 2017

volume

22

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27 August 2017

issue

7

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27 August 2017

page(s)

735-746

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The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies

27 August 2017

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A new frontier in the treatment of cancer: NK-1 receptor antagonists

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The NK-1 receptor: a new target in cancer therapy

21 January 2018

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NK-1 receptor antagonists: a new paradigm in pharmacological therapy

21 January 2018

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Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells

21 January 2018

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Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs

21 January 2018

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Anti-tumour activity of tachykinin NK1 receptor antagonists on human glioma U373 MG xenograft

21 January 2018

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Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231.

21 January 2018

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Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis

21 January 2018

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Neurokinin-1 receptors located in human retinoblastoma cell lines: antitumor action of its antagonist, L-732,138.

21 January 2018

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Cell proliferation associated with actions of the substance P/NK-1 receptor complex in keratocystic odontogenic tumours

21 January 2018

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Expression of substance P and neurokinin-1-receptor in laryngeal cancer: linking chronic inflammation to cancer promotion and progression.

21 January 2018

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Substance P immunoreactive nerve fibres are related to gastric cancer differentiation status and could promote proliferation and migration of gastric cancer cells

21 January 2018

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Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-A peptides

21 January 2018

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Transcription factors in the pathogenesis of autoimmunity

21 January 2018

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Nuclear factor-kappaB is central to the expression of truncated neurokinin-1 receptor in breast cancer: implication for breast cancer cell quiescence within bone marrow stroma

21 January 2018

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The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines

21 January 2018

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The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines

21 January 2018

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Antitumoral action of the neurokinin-1-receptor antagonist L-733,060 and mitogenic action of substance P on human retinoblastoma cell lines

21 January 2018

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The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines

21 January 2018

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Substance P activates responses correlated with tumour growth in human glioma cell lines bearing tachykinin NK1 receptors

21 January 2018

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NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2.

21 January 2018

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Detection of stable N-terminal protachykinin A immunoreactivity in human plasma and cerebrospinal fluid

21 January 2018

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Mimicry between neurokinin-1 and fibronectin may explain the transport and stability of increased substance P immunoreactivity in patients with bone marrow fibrosis.

21 January 2018

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Neurotransmitters are regulators for the migration of tumor cells and leukocytes

21 January 2018

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Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism

21 January 2018

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Cell motility through plasma membrane blebbing

21 January 2018

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The tachykinin NK1 receptor. Part I: Ligands and mechanisms of cellular activation

21 January 2018

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Tachykinin receptors antagonists: from research to clinic

21 January 2018

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The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test

21 January 2018

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Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice.

21 January 2018

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Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury

21 January 2018

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Medicinal chemistry of selective neurokinin-1 antagonists

21 January 2018

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NK-1 as a melanoma target.

21 January 2018

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Fosaprepitant (MK-0517): a neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting

21 January 2018

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The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug

21 January 2018

1 reference

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Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist

21 January 2018

1 reference

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Neurokinin-1 receptor antagonists: a comprehensive patent survey

21 January 2018

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Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting

21 January 2018

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Potential of substance P antagonists as antiemetics

21 January 2018

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Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy

21 January 2018

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A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas

21 January 2018

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The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2012.697153

A role for substance P in cancer promotion and progression: a mechanism to counteract intracellular death signals following oncogene activation or DNA damage

21 January 2018

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Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer

21 January 2018

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Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis?

21 January 2018

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Paravertebral anesthesia: how substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence

21 January 2018

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Role of substance P in hypersensitivity reactions induced by paclitaxel, an anticancer agent

21 January 2018

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Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2012.697153

The neurobiology of vascular head pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2012.697153

Neurokinin-1 (NK-1) receptor antagonists abrogate methamphetamine-induced striatal dopaminergic neurotoxicity in the murine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2012.697153

Implication of possible therapies targeted for the tachykinergic system with the biology of neurokinin receptors and emerging related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2012.697153

10.1517/13543776.2012.697153

21 January 2018

Identifiers

DOI

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release_nf3jq4auzvhulfnjeu43ornzvq

27 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/nf3jq4auzvhulfnjeu43ornzvq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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