New biomarkers and targets in pancreatic cancer and their application to treatment (Q38021692)

27 August 2017

New biomarkers and targets in pancreatic cancer and their application to treatment (English)

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27 August 2017

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Eithne Costello

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John P Neoptolemos

object named as

John P Neoptolemos

series ordinal

3

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William Greenhalf

series ordinal

2

object named as

William Greenhalf

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PubMed ID

22733351

27 August 2017

language of work or name

English

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publication date

26 June 2012

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Nature Reviews Gastroenterology & Hepatology

27 August 2017

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27 August 2017

9

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27 August 2017

8

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27 August 2017

435-444

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https://scigraph.springernature.com/pub.10.1038/nrgastro.2012.119

27 August 2017

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Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial

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Deoxycitidine kinase is associated with prolonged survival after adjuvant gemcitabine for resected pancreatic adenocarcinoma

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Detection of circulating tumor cells in patients with pancreatic cancer: a preliminary result

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Stromal biology and therapy in pancreatic cancer.

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Co-evolution of tumor cells and their microenvironment

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New treatment options for advanced pancreatic cancer

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Targeting the cancer initiating cell: the ultimate target for cancer therapy.

21 January 2018

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Development and characterization of gemcitabine-resistant pancreatic tumor cells.

21 January 2018

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Notch signalling in solid tumours: a little bit of everything but not all the time

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Targeting Notch signaling in pancreatic cancer

21 January 2018

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Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma

21 January 2018

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Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

21 January 2018

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KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

21 January 2018

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Cancer. Breaching the cancer fortress

21 January 2018

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Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

21 January 2018

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An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

21 January 2018

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CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

21 January 2018

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PARP inhibition: PARP1 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Expression of glial cell line-derived neurotrophic factor family members and their receptors in pancreatic cancers

21 January 2018

1 reference

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Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial

21 January 2018

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Baseline Circulating Tumor Cell Counts Significantly Enhance a Prognostic Score for Patients Participating in Phase I Oncology Trials

21 January 2018

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New approaches to the treatment of pancreatic cancer: from tumor-directed therapy to immunotherapy

21 January 2018

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Understanding metastasis in pancreatic cancer: a call for new clinical approaches

21 January 2018

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31 March 2020

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The role of stroma in pancreatic cancer: diagnostic and therapeutic implications

31 March 2020

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Enhancing the translation of cancer biomarkers

31 March 2020

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microRNAs as markers of survival and chemoresistance in pancreatic ductal adenocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Molecular detection of circulating cancer cells during surgery in patients with biliary-pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Cancer stem cells: an evolving concept

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

c-Met is a marker of pancreatic cancer stem cells and therapeutic target

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

The hedgehog pathway and pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

BRCA2 germline mutations in familial pancreatic carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Familial pancreatic cancer--current knowledge

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.119

Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancer

31 March 2020

1 reference

12 December 2020

HuR status is a powerful marker for prognosis and response to gemcitabine-based chemotherapy for resected pancreatic ductal adenocarcinoma patients

1 reference

12 December 2020

K-ras mutations in pancreatic ductal proliferative lesions

1 reference

12 December 2020

Targeting notch to eradicate pancreatic cancer stem cells for cancer therapy.

1 reference

12 December 2020

Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism

1 reference

12 December 2020

Biology and management of pancreatic cancer

1 reference

12 December 2020

10.1038/NRGASTRO.2012.119

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

22733351