Prevention and treatment of type 1 diabetes mellitus by the manipulation of invariant natural killer T cells (Q38028844)

27 August 2017

title

Prevention and treatment of type 1 diabetes mellitus by the manipulation of invariant natural killer T cells (English)

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27 August 2017

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Jan Novak

1

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27 August 2017

Lucie Novakova

series ordinal

2

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27 August 2017

publication date

24 July 2012

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Clinical and Experimental Medicine

27 August 2017

published in

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27 August 2017

volume

13

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27 August 2017

issue

4

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27 August 2017

page(s)

229-237

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https://scigraph.springernature.com/pub.10.1007/s10238-012-0199-0

27 August 2017

exact match

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

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In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

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CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system

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Raising the NKT cell family

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Distinct functional lineages of human V(alpha)24 natural killer T cells

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Differential antitumor immunity mediated by NKT cell subsets in vivo

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A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity

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Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia.

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Phenotypic and functional differences between NKT cells colonizing splanchnic and peripheral lymph nodes.

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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Regulatory T cells under scrutiny

21 January 2018

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Natural killer T cells: natural or unnatural regulators of autoimmunity?

21 January 2018

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Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

21 January 2018

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Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

21 January 2018

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CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

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CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice

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Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus.

21 January 2018

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Testing the NKT cell hypothesis of human IDDM pathogenesis

21 January 2018

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Frequency and function of circulating invariant NKT cells in autoimmune diabetes mellitus and thyroid diseases in Colombian patients.

21 January 2018

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Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice

21 January 2018

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21 January 2018

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Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

21 January 2018

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Invariant NKT cells exacerbate type 1 diabetes induced by CD8 T cells.

21 January 2018

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alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles

21 January 2018

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21 January 2018

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Expansion of human Valpha24+ NKT cells by repeated stimulation with KRN7000.

21 January 2018

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21 January 2018

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NKT-cell-based immunotherapies in clinical trials.

21 January 2018

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Lipid and glycolipid antigens of CD1d-restricted natural killer T cells

21 January 2018

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Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial.

21 January 2018

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Immune intervention in type 1 diabetes.

21 January 2018

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

21 January 2018

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

21 January 2018

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Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

21 January 2018

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C-peptide an adequate endpoint in type 1 diabetes

21 January 2018

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Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes

21 January 2018

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Prevention of diabetes in nonobese diabetic mice mediated by CD1d-restricted nonclassical NKT cells

21 January 2018

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12 December 2020

NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes

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12 December 2020

Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of V alpha 14 NK T cells

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12 December 2020

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

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12 December 2020

Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells

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12 December 2020

NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

1 reference

12 December 2020

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

1 reference

12 December 2020

Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies

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12 December 2020

Inhibition of T cell differentiation into effectors by NKT cells requires cell contacts

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12 December 2020

Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice

1 reference

12 December 2020

High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes

1 reference

12 December 2020

Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells

1 reference

12 December 2020

Repeated -Galactosylceramide Administration Results in Expansion of NK T Cells and Alleviates Inflammatory Dermatitis in MRL-lpr/lpr Mice

1 reference

12 December 2020

Immunoregulatory Role of CD1d in the Hydrocarbon Oil-Induced Model of Lupus Nephritis

1 reference

12 December 2020

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

1 reference

12 December 2020

Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11

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12 December 2020

Potent expansion of human natural killer T cells using alpha-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15

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12 December 2020

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors

1 reference

12 December 2020

Latent autoimmune diabetes mellitus in adults (LADA): the role of antibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency

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12 December 2020

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

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12 December 2020

Immune regulatory T cells in siblings of children suffering from type 1 diabetes mellitus

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12 December 2020

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

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12 December 2020

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator

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12 December 2020

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

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12 December 2020

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

1 reference

12 December 2020

10.1007/S10238-012-0199-0

Identifiers

DOI

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Dimensions Publication ID

27 August 2017

1002335254

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