Digital PCR strategies in the development and analysis of molecular biomarkers for personalized medicine (Q38038452)

27 August 2017

Digital PCR strategies in the development and analysis of molecular biomarkers for personalized medicine (English)

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27 August 2017

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personalized medicine

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Elizabeth Day

1

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PubMed ID

22926236

27 August 2017

Paul H Dear

series ordinal

2

1 reference

PubMed ID

22926236

27 August 2017

Frank McCaughan

series ordinal

3

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27 August 2017

19 August 2012

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27 August 2017

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27 August 2017

59

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27 August 2017

1

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27 August 2017

101-107

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

27 August 2017

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Principle and applications of digital PCR

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Mathematical analysis of copy number variation in a DNA sample using digital PCR on a nanofluidic device

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Interrogation of genomes by molecular copy-number counting (MCC).

7 January 2021

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Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results

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High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

7 January 2021

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Evaluation of digital PCR for absolute DNA quantification

7 January 2021

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Evaluation of a droplet digital polymerase chain reaction format for DNA copy number quantification

7 January 2021

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Single molecule detection in nanofluidic digital array enables accurate measurement of DNA copy number

7 January 2021

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BEAMing up for detection and quantification of rare sequence variants.

7 January 2021

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Development of personalized tumor biomarkers using massively parallel sequencing

7 January 2021

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Absolute quantitative detection of ABL tyrosine kinase domain point mutations in chronic myeloid leukemia using a novel nanofluidic platform and mutation-specific PCR.

7 January 2021

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Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

7 January 2021

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Inferring tumor progression from genomic heterogeneity

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Relative impact of nucleotide and copy number variation on gene expression phenotypes

7 January 2021

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Taking qPCR to a higher level: Analysis of CNV reveals the power of high throughput qPCR to enhance quantitative resolution

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7 January 2021

Megapixel digital PCR.

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Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

7 January 2021

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Microdissection molecular copy-number counting (microMCC)--unlocking cancer archives with digital PCR

7 January 2021

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Comprehensive human genome amplification using multiple displacement amplification

7 January 2021

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Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.

7 January 2021

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Sensitive quantitation of minimal residual disease in chronic myeloid leukemia using nanofluidic digital polymerase chain reaction assay.

7 January 2021

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Digital PCR provides sensitive and absolute calibration for high throughput sequencing

7 January 2021

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Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

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The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

7 January 2021

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Effect of sustained elevated temperature prior to amplification on template copy number estimation using digital polymerase chain reaction.

7 January 2021

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Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer

7 January 2021

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Genomic evidence of pre-invasive clonal expansion, dispersal and progression in bronchial dysplasia

7 January 2021

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

7 January 2021

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Biomarkers of response to epidermal growth factor receptor inhibitors in Non-Small-Cell Lung Cancer Working Group: standardization for use in the clinical trial setting.

7 January 2021

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Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.

7 January 2021

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Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays

7 January 2021

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Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

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High-resolution characterization of a hepatocellular carcinoma genome

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Genetic variegation of clonal architecture and propagating cells in leukaemia

7 January 2021

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Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.

7 January 2021

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Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer.

7 January 2021

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Cell-free nucleic acids as biomarkers in cancer patients

7 January 2021

1 reference

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Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients

7 January 2021

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Digital PCR for the molecular detection of fetal chromosomal aneuploidy

7 January 2021

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Implementing prenatal diagnosis based on cell-free fetal DNA: accurate identification of factors affecting fetal DNA yield

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Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study

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Universal noninvasive detection of solid organ transplant rejection

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Copy number variants and pharmacogenomics

7 January 2021

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Genomics and drug response

7 January 2021

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Quantification noise in single cell experiments

7 January 2021

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Clinical outcome prediction by microRNAs in human cancer: a systematic review

7 January 2021

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MicroRNAs in metabolism and metabolic disorders

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Comprehensive microRNA expression profiling of the hematopoietic hierarchy

7 January 2021

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A decade of exploring the cancer epigenome - biological and translational implications

7 January 2021

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The implications of heterogeneous DNA methylation for the accurate quantification of methylation

7 January 2021

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DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

7 January 2021

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Single molecule epigenetic analysis in a nanofluidic channel.

7 January 2021

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Digital PCR on a SlipChip

7 January 2021

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Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

7 January 2021

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Studying copy number variations using a nanofluidic platform

7 January 2021

1 reference

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Spinning disk platform for microfluidic digital polymerase chain reaction

7 January 2021

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BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

7 January 2021

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High-throughput quantitative polymerase chain reaction in picoliter droplets

7 January 2021

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CONTRA: copy number analysis for targeted resequencing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMETH.2012.08.001

Comprehensive qPCR profiling of gene expression in single neuronal cells

7 January 2021

1 reference

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Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance

7 January 2021

1 reference

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10.1016/J.YMETH.2012.08.001

7 January 2021

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

22926236