Roles of toll-like receptors in cancer: a double-edged sword for defense and offense (Q38039958)

27 August 2017

Roles of toll-like receptors in cancer: a double-edged sword for defense and offense (English)

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27 August 2017

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Shaherin Basith

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27 August 2017

Balachandran Manavalan

2

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27 August 2017

Tae Hyeon Yoo

3

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27 August 2017

Sang Geon Kim

4

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27 August 2017

Sangdun Choi

5

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27 August 2017

language of work or name

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1 August 2012

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Archives of Pharmacal Research

27 August 2017

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27 August 2017

35

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27 August 2017

8

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27 August 2017

1297-1316

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https://scigraph.springernature.com/pub.10.1007/s12272-012-0802-7

27 August 2017

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Activation of Toll-like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor growth

21 January 2018

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Inflammation, cancer and chemoresistance: taking advantage of the toll-like receptor signaling pathway

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Cancers take their Toll--the function and regulation of Toll-like receptors in cancer cells

21 January 2018

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Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

21 January 2018

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Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells

21 January 2018

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Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion.

21 January 2018

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Antitumour effect of OM-174 and cyclophosphamide on murine B16 melanoma in different experimental conditions.

21 January 2018

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Case-control study of human papillomavirus and oropharyngeal cancer

21 January 2018

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Human lung cancer cells express functionally active Toll-like receptor 9

21 January 2018

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An exploratory study of systemic administration of the toll-like receptor-7 agonist 852A in patients with refractory metastatic melanoma

21 January 2018

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Polymorphisms in Toll-like receptor genes and risk of cancer

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Masquerader: high mobility group box-1 and cancer

21 January 2018

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Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

21 January 2018

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Cancer relapse under chemotherapy: why TLR2/4 receptor agonists can help

21 January 2018

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Unleashing the therapeutic potential of NOD-like receptors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Primary leukocyte screens for innate immune agonists.

21 January 2018

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Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Activation of Toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

21 January 2018

The Hallmarks of Cancer

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Comparison of human B cell activation by TLR7 and TLR9 agonists

21 January 2018

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Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Intracellular expression of toll-like receptor 4 in neuroblastoma cells and their unresponsiveness to lipopolysaccharide

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Small interfering RNA-directed targeting of Toll-like receptor 4 inhibits human prostate cancer cell invasion, survival, and tumorigenicity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptors on tumor cells facilitate evasion of immune surveillance

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling

21 January 2018

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TLR signaling by tumor and immune cells: a double-edged sword

21 January 2018

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Toll like receptor-9 agonists stimulate prostate cancer invasion in vitro

21 January 2018

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Innate immune recognition

21 January 2018

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Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors

21 January 2018

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Poly I:C enhances cycloheximide-induced apoptosis of tumor cells through TLR3 pathway

21 January 2018

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

21 January 2018

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Abrogation of TLR4 and CD14 expression and signaling in human adrenocortical tumors

21 January 2018

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Pathogen recognition with Toll-like receptors

21 January 2018

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

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TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Anti-tumor effect of DNA-based vaccination and dSLIM immunomodulatory molecules in mice with Ph+ acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptor 9 (TLR9) agonists in the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Increased toll-like receptor 9 expression in cervical neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Signaling pathways downstream of pattern-recognition receptors and their cross talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Potential therapeutic interventions for fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Cancer-related inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Neonatal innate immunity to infectious agents

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Functionally active toll-like receptor 3 on human primary and metastatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Tolerance, danger, and the extended family

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

The danger model: a renewed sense of self

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

High basal levels of functional toll-like receptor 3 (TLR3) and noncanonical Wnt5a are expressed in papillary thyroid cancer and are coordinately decreased by phenylmethimazole together with cell proliferation and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Activation of Toll-like receptor 2 by a novel preparation of cell wall skeleton from Mycobacterium bovis BCG Tokyo (SMP-105) sufficiently enhances immune responses against tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptor 2 is present in the microenvironment of oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

How Toll-like receptors signal: what we know and what we don't know

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

The Toll-IL-1 receptor adaptor family grows to five members.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Immunobiology of Toll-like receptors: emerging trends

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Physiological and molecular mechanisms of lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Increased expression of toll-like receptors (TLR) 2, 4 and 5 in gastric dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Regulation of TLR4-induced IL-6 response in bladder cancer cells by opposing actions of MAPK and PI3K signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Absent Toll-like receptor-9 expression predicts poor prognosis in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

TLR3 can directly trigger apoptosis in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Therapeutic anti-tumor immunity triggered by injections of immunostimulating single-stranded RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

TLR7 and TLR8 as targets in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Overexpression of TLR3, TLR4, TLR7 and TLR9 in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptors 3 and 7 agonists enhance tumor cell lysis by human gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Role of neutrophils in BCG immunotherapy for bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Triggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

21 January 2018

TLR signaling pathways

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https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Expression and functional research of TLR4 in human colon carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Morphological study on Mycobacterium bovis BCG Tokyo 172 cell wall skeleton (SMP-105).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Endotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Reduced expression of Toll-like receptor 4 inhibits human breast cancer cells proliferation and inflammatory cytokines secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptors expressed in tumor cells: targets for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Exogenous or endogenous Toll-like receptor ligands: which is the MVP in tumorigenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Expression and significance of TLR4 and HIF-1alpha in pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

TLR3 activation inhibits nasopharyngeal carcinoma metastasis via downregulation of chemokine receptor CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Increased expression of Toll-like receptors 4 and 9 in human lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Mammalian toll-like receptors: from endogenous ligands to tissue regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Toll-like receptor expression in normal ovary and ovarian tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Sequence variants in toll-like receptor 10 are associated with nasopharyngeal carcinoma risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Characterization of bovine Toll-like receptor 8: ligand specificity, signaling essential sites and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

Sequence Variants of Toll-Like Receptor 4 and Susceptibility to Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12272-012-0802-7

10.1007/S12272-012-0802-7

21 January 2018

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DOI

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Dimensions Publication ID

27 August 2017

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1 reference