Life, death, and miracles: Th17 cells in the intestine (Q38040744)

27 August 2017

Life, death, and miracles: Th17 cells in the intestine (English)

1 reference

27 August 2017

3

Richard A Flavell

1 reference

27 August 2017

Samuel Huber

1

1 reference

PubMed ID

22949322

27 August 2017

Nicola Gagliani

series ordinal

2

1 reference

PubMed ID

22949322

27 August 2017

language of work or name

English

0 references

publication date

1 September 2012

1 reference

European Journal of Immunology

27 August 2017

1 reference

27 August 2017

42

1 reference

27 August 2017

2238-2245

1 reference

27 August 2017

9

1 reference

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

27 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Peripheral education of the immune system by colonic commensal microbiota.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Induction of intestinal Th17 cells by segmented filamentous bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-23 drives intestinal inflammation through direct activity on T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Control of TH17 cells occurs in the small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

ATP drives lamina propria T(H)17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The dual nature of TH17 cells: shifting the focus to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-17 and lung host defense against Klebsiella pneumoniae infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The biological functions of T helper 17 cell effector cytokines in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-17 and type 17 helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Increased expression of interleukin 17 in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Phenotypic and functional features of human Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Late developmental plasticity in the T helper 17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Regulation of inflammatory responses by IL-17F

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

State of the art: IBD therapy and clinical trials in IBD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Chromatin signatures of pluripotent cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Developmental plasticity of Th17 and Treg cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Differential effect of IL-27 on developing versus committed Th17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Inflammatory effects of ex vivo human Th17 cells are suppressed by regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

The effect of infections on susceptibility to autoimmune and allergic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Hepatosplenic T-cell lymphoma in patients receiving TNF-α inhibitor therapy: expanding the groups at risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Infliximab, azathioprine, or combination therapy for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Evidence for a cross-talk between human neutrophils and Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

7 January 2021

Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

7 January 2021

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

7 January 2021

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

7 January 2021

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201242619

7 January 2021

Identifiers

DOI

10.1002/EJI.201242619

1 reference

27 August 2017

1 reference

PubMed ID

22949322