Multi-level regulation of cellular recognition of viral dsRNA. (Q38041927)

27 August 2017

Multi-level regulation of cellular recognition of viral dsRNA. (English)

1 reference

27 August 2017

Alys Peisley

1

1 reference

PubMed ID

22960755

27 August 2017

Sun Hur

series ordinal

2

1 reference

27 August 2017

9 September 2012

1 reference

Cellular and Molecular Life Sciences

27 August 2017

1 reference

27 August 2017

70

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27 August 2017

11

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27 August 2017

1949-1963

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https://scigraph.springernature.com/pub.10.1007/s00018-012-1149-4

27 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency

21 January 2018

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Regulation of serotonin-2C receptor G-protein coupling by RNA editing

21 January 2018

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21 January 2018

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21 January 2018

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RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The Effect of RNA Editing and ADARs on miRNA Biogenesis and Function

21 January 2018

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RNA editing in regulating gene expression in the brain

21 January 2018

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Nuclear Editing of mRNA 3'-UTRs

21 January 2018

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Effects of length and location on the cellular response to double-stranded RNA.

21 January 2018

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ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

21 January 2018

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Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis

21 January 2018

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Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1

21 January 2018

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Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene

21 January 2018

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Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

21 January 2018

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A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity

21 January 2018

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RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans

21 January 2018

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The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove

21 January 2018

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RNA recognition by a Staufen double-stranded RNA-binding domain

21 January 2018

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Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.

21 January 2018

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2'-5' oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme

21 January 2018

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Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase

21 January 2018

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The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities

21 January 2018

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Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease.

21 January 2018

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New insights into the role of RNase L in innate immunity

21 January 2018

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Identification of 2'-phosphodiesterase, which plays a role in the 2-5A system regulated by interferon

21 January 2018

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The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties

21 January 2018

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A diverse range of gene products are effectors of the type I interferon antiviral response

21 January 2018

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Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

21 January 2018

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The nature of the catalytic domain of 2'-5'-oligoadenylate synthetases

21 January 2018

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Activation of 2'-5' oligoadenylate synthetase by single-stranded and double-stranded RNA aptamers

21 January 2018

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Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein.

21 January 2018

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2'-5'-Oligoadenylate synthetase is activated by a specific RNA sequence motif

21 January 2018

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Heterogeneous Nuclear RNA Promotes Synthesis of (2′,5′)Oligoadenylate and Is Cleaved by the (2′,5′)Oligoadenylate-Activated Endoribonuclease

21 January 2018

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Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells

21 January 2018

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Pathogen recognition by innate receptors.

21 January 2018

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21 January 2018

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Evolution of the chicken Toll-like receptor gene family: a story of gene gain and gene loss

21 January 2018

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

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Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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Dimerization of Toll-like receptor 3 (TLR3) is required for ligand binding

21 January 2018

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The TLR3 signaling complex forms by cooperative receptor dimerization

21 January 2018

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

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The molecular structure of the Toll-like receptor 3 ligand-binding domain.

21 January 2018

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Structures of the toll-like receptor family and its ligand complexes

21 January 2018

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

21 January 2018

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Innate sensing of self and non-self RNAs by Toll-like receptors

21 January 2018

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TLR3 in antiviral immunity: key player or bystander?

21 January 2018

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mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

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TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

21 January 2018

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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

21 January 2018

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Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

21 January 2018

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Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

21 January 2018

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

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Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

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LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

21 January 2018

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Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

21 January 2018

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

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Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

21 January 2018

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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

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Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

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A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

21 January 2018

1 reference

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

21 January 2018

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Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

21 January 2018

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Small self-RNA generated by RNase L amplifies antiviral innate immunity

21 January 2018

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Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

21 January 2018

1 reference

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The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

21 January 2018

1 reference

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The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

21 January 2018

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Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

21 January 2018

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Structural basis of RNA recognition and activation by innate immune receptor RIG-I

21 January 2018

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Structural Insights into RNA Recognition by RIG-I

21 January 2018

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Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

21 January 2018

1 reference

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Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

21 January 2018

1 reference

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Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2

21 January 2018

1 reference

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Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

21 January 2018

1 reference

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

21 January 2018

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Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

21 January 2018

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MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1149-4

MDA-5 recognition of a murine norovirus

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1149-4

Activation of MDA5 requires higher-order RNA structures generated during virus infection

21 January 2018

1 reference

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Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

21 January 2018

1 reference

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

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Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

21 January 2018

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DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells

21 January 2018

1 reference

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DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells

21 January 2018

1 reference

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Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1149-4

The DEAD-box RNA helicase DDX1 interacts with RelA and enhances nuclear factor kappaB-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1149-4

Targeting Toll-like receptors: emerging therapeutics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1149-4

RIG-I like receptors in antiviral immunity and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1149-4

The dsRNA binding protein family: critical roles, diverse cellular functions

21 January 2018

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12 December 2020

An unwinding activity that covalently modifies its double-stranded RNA substrate

1 reference

12 December 2020

Double-stranded RNA adenosine deaminases ADAR1 and ADAR2 have overlapping specificities

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12 December 2020

A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation

1 reference

12 December 2020

The effect of RNA editing and ADARs on miRNA biogenesis and function.

1 reference

12 December 2020

Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

1 reference

12 December 2020

Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies

1 reference

12 December 2020

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

1 reference

12 December 2020

Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease

1 reference

12 December 2020

Specific recognition of HIV TAR RNA by the dsRNA binding domains (dsRBD1-dsRBD2) of PKR

1 reference

12 December 2020

Effects of varying lengths of double-stranded RNA on binding and activation of 2'-5'-oligoadenylate synthetase

1 reference

12 December 2020

The importance of internal loops within RNA substrates of ADAR1

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12 December 2020

RNA editing in hepatitis delta virus

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12 December 2020

Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase.

1 reference

12 December 2020

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

12 December 2020

Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure

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12 December 2020

10.1007/S00018-012-1149-4

Identifiers

DOI

1 reference

27 August 2017

0 references

1 reference

PubMed ID

22960755