Tools to therapeutically harness the human antibody response (Q38046109)

27 August 2017

Tools to therapeutically harness the human antibody response (English)

1 reference

27 August 2017

1 reference

Patrick C Wilson

1

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PubMed ID

23007571

27 August 2017

Sarah F Andrews

series ordinal

2

1 reference

27 August 2017

1 October 2012

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Nature Reviews Immunology

27 August 2017

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27 August 2017

12

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27 August 2017

10

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27 August 2017

709-719

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Passive antibody therapy for infectious diseases

27 August 2017

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Continuous cultures of fused cells secreting antibody of predefined specificity

31 March 2020

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31 March 2020

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Potent antibody therapeutics by design

31 March 2020

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Therapeutic antibodies for autoimmunity and inflammation

31 March 2020

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Monoclonal antibodies: versatile platforms for cancer immunotherapy

31 March 2020

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Beyond natural antibodies: the power of in vitro display technologies

31 March 2020

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A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood.

31 March 2020

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A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

31 March 2020

1 reference

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

31 March 2020

1 reference

The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific

31 March 2020

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The growth and potential of human antiviral monoclonal antibody therapeutics.

31 March 2020

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EB virus-induced B lymphocyte cell lines producing specific antibody

31 March 2020

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Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV).

31 March 2020

1 reference

Characterization of human monoclonal antibodies specific to the hepatitis C virus glycoprotein E2 with in vitro binding neutralization properties

31 March 2020

1 reference

Human monoclonal antibodies.

31 March 2020

1 reference

Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

31 March 2020

1 reference

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

31 March 2020

1 reference

A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin

31 March 2020

1 reference

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

31 March 2020

1 reference

Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses

31 March 2020

1 reference

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.

31 March 2020

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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

31 March 2020

1 reference

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

31 March 2020

1 reference

Broad neutralization coverage of HIV by multiple highly potent antibodies

31 March 2020

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Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex

31 March 2020

1 reference

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

31 March 2020

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Cross-reacting antibodies enhance dengue virus infection in humans

31 March 2020

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Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection

31 March 2020

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Neutralizing and non-neutralizing monoclonal antibodies against dengue virus E protein derived from a naturally infected patient

31 March 2020

1 reference

Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

31 March 2020

1 reference

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection

31 March 2020

1 reference

Chikungunya virus envelope-specific human monoclonal antibodies with broad neutralization potency

31 March 2020

1 reference

Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients.

31 March 2020

1 reference

An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies

31 March 2020

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Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming

31 March 2020

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Predominant autoantibody production by early human B cell precursors

31 March 2020

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B-cell self-tolerance in humans

31 March 2020

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Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

31 March 2020

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The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases

31 March 2020

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Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

31 March 2020

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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.

31 March 2020

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Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

31 March 2020

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Human monoclonals from antigen-specific selection of B lymphocytes and transformation by EBV.

31 March 2020

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Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles

31 March 2020

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Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

31 March 2020

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A method for identification of HIV gp140 binding memory B cells in human blood

31 March 2020

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Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa.

31 March 2020

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High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions.

31 March 2020

1 reference

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

31 March 2020

1 reference

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

31 March 2020

1 reference

Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

31 March 2020

1 reference

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

31 March 2020

1 reference

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

31 March 2020

1 reference

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

31 March 2020

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Kinetic, affinity, and diversity limits of human polyclonal antibody responses against tetanus toxoid

31 March 2020

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High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies

31 March 2020

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Maintenance of serological memory by polyclonal activation of human memory B cells.

31 March 2020

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Parenteral influenza vaccination induces a rapid systemic and local immune response

31 March 2020

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Comparison of the influenza virus-specific effector and memory B-cell responses to immunization of children and adults with live attenuated or inactivated influenza virus vaccines.

31 March 2020

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Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

31 March 2020

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Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

31 March 2020

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Isolation of human antibody repertoires with preservation of the natural heavy and light chain pairing

31 March 2020

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Limits for antibody affinity maturation and repertoire diversification in hypervaccinated humans

31 March 2020

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Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies

31 March 2020

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H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination

31 March 2020

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Systems analysis of adaptive immunity by utilization of high-throughput technologies

31 March 2020

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Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

31 March 2020

1 reference

A proteomics approach for the identification and cloning of monoclonal antibodies from serum

31 March 2020

1 reference

Targeting B cell responses in universal influenza vaccine design

31 March 2020

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Antibody recognition of a highly conserved influenza virus epitope

31 March 2020

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Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

31 March 2020

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Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

31 March 2020

1 reference

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

31 March 2020

1 reference

Pandemic H1N1 Influenza Infection and Vaccination in Humans Induces Cross-Protective Antibodies that Target the Hemagglutinin Stem

31 March 2020

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Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

31 March 2020

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The immune response during acute HIV-1 infection: clues for vaccine development

31 March 2020

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GP120: target for neutralizing HIV-1 antibodies

31 March 2020

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Prospects for an HIV vaccine: leading B cells down the right path

31 March 2020

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HIV-1 and influenza antibodies: seeing antigens in new ways

31 March 2020

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Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

31 March 2020

1 reference

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

31 March 2020

1 reference

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

31 March 2020

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

31 March 2020

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B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

31 March 2020

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Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

31 March 2020

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Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

31 March 2020

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Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

31 March 2020

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

31 March 2020

1 reference

Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza

31 March 2020

1 reference

A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses.

31 March 2020

1 reference

Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies

31 March 2020

1 reference

Immunodominance of the VH1-46 Antibody Gene Segment in the Primary Repertoire of Human Rotavirus-Specific B Cells Is Reduced in the Memory Compartment through Somatic Mutation of Nondominant Clones

31 March 2020

1 reference

Human monoclonal antibodies against Mycobacterium leprae

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23007571

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23007571

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

By-passing immunization: building high affinity human antibodies by chain shuffling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23007571

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI3285

1 reference

27 August 2017

0 references

1 reference

PubMed ID

23007571