Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality? (Q38063960)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199318%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

review article

1 reference

title

Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality? (English)

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19 February 2020

2

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19 February 2020

Agnes Lehuen

5

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19 February 2020

author name string

Y Simoni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199318%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

L Ghazarian

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199318%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

L Beaudoin

4

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19 February 2020

publication date

1 January 2013

1 reference

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Clinical and Experimental Immunology

19 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199318%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

171

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19 February 2020

page(s)

8-19

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19 February 2020

issue

1

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Lipid-antigen presentation by CD1d(+) B cells is essential for the maintenance of invariant natural killer T cells

19 February 2020

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31 August 2018

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31 August 2018

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Immune cell crosstalk in type 1 diabetes

31 August 2018

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Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a beta-linked self-glycolipid

31 August 2018

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31 August 2018

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Invariant NKT cells limit activation of autoreactive CD1d-positive B cells.

31 August 2018

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A novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient state

31 August 2018

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Natural killer T cells are important in the pathogenesis of asthma: the many pathways to asthma

31 August 2018

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Natural killer T cells are not the predominant T cell in asthma and likely modulate, not cause, asthma

31 August 2018

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31 August 2018

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31 August 2018

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An alpha-galactosylceramide C20:2 N-acyl variant enhances anti-inflammatory and regulatory T cell-independent responses that prevent type 1 diabetes.

31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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Invariant NKT cells regulate experimental autoimmune encephalomyelitis and infiltrate the central nervous system in a CD1d-independent manner

31 August 2018

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31 August 2018

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Liver autoimmunity triggered by microbial activation of natural killer T cells

31 August 2018

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MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells

31 August 2018

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Activation of keratinocyte protein kinase C zeta in psoriasis plaques

31 August 2018

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Natural killer T cells and innate immune B cells from lupus-prone NZB/W mice interact to generate IgM and IgG autoantibodies

31 August 2018

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Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease

31 August 2018

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Modulation of Valpha19 NKT cell immune responses by alpha-mannosyl ceramide derivatives consisting of a series of modified sphingosines.

31 August 2018

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31 August 2018

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31 August 2018

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Examining the role of CD1d and natural killer T cells in the development of nephritis in a genetically susceptible lupus model

31 August 2018

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31 August 2018

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FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation

31 August 2018

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31 August 2018

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CD1d ligation on human monocytes directly signals rapid NF-kappaB activation and production of bioactive IL-12.

31 August 2018

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31 August 2018

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Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black x New Zealand White)F1 mice

31 August 2018

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Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis

31 August 2018

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Anatomy of CD1-lipid antigen complexes

31 August 2018

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31 August 2018

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alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles

31 August 2018

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NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor beta1 production

31 August 2018

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Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice

31 August 2018

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Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells

31 August 2018

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CD1d-restricted T cell activation by nonlipidic small molecules

31 August 2018

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The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation

31 August 2018

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CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice

31 August 2018

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Natural killer T cells accelerate atherogenesis in mice.

31 August 2018

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Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

31 August 2018

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NKT cells: what's in a name?

31 August 2018

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Autoimmune and inflammatory mechanisms in atherosclerosis

31 August 2018

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Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL-4 and eotaxin production.

31 August 2018

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CD1d-dependent activation of NKT cells aggravates atherosclerosis.

31 August 2018

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Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide

31 August 2018

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Low expression levels of soluble CD1d gene in patients with rheumatoid arthritis.

31 August 2018

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Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

31 August 2018

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Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein

31 August 2018

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Role of CD1d in coxsackievirus B3-induced myocarditis.

31 August 2018

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Testing the NKT cell hypothesis of human IDDM pathogenesis

31 August 2018

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Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity

31 August 2018

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Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice.

31 August 2018

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Presentation of the same glycolipid by different CD1 molecules

31 August 2018

1 reference

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Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining

31 August 2018

1 reference

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Multiple immuno-regulatory defects in type-1 diabetes

31 August 2018

1 reference

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Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

31 August 2018

1 reference

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Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

31 August 2018

1 reference

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Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

31 August 2018

1 reference

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A major fraction of human bone marrow lymphocytes are Th2-like CD1d-reactive T cells that can suppress mixed lymphocyte responses.

31 August 2018

1 reference

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A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

31 August 2018

1 reference

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Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

31 August 2018

1 reference

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Human double-negative T cells in systemic lupus erythematosus provide help for IgG and are restricted by CD1c

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

Murine CD1d-restricted T cell recognition of cellular lipids

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

Self glycolipids as T-cell autoantigens

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimm

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530090

High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes

31 August 2018

1 reference

12 December 2020

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

1 reference

12 December 2020

Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission

1 reference

12 December 2020

Cutting edge: invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model

1 reference

12 December 2020

Repeated -Galactosylceramide Administration Results in Expansion of NK T Cells and Alleviates Inflammatory Dermatitis in MRL-lpr/lpr Mice

1 reference

12 December 2020

Innate immunity modulates autoimmunity: type 1 interferon-beta treatment in multiple sclerosis promotes growth and function of regulatory invariant natural killer T cells through dendritic cell maturation

1 reference

12 December 2020

Peripheral NK1.1- NKT Cells Are Mature and Functionally Distinct from Their Thymic Counterparts

1 reference

12 December 2020

Rituximab treatment overcomes reduction of regulatory iNKT cells in patients with rheumatoid arthritis

1 reference

12 December 2020

Early activation of invariant natural killer T cells in a rheumatoid arthritis model and application to disease treatment

1 reference

12 December 2020

Atherosclerotic Abdominal Aortic Aneurysm and the Interaction Between Autologous Human Plaque-Derived Vascular Smooth Muscle Cells, Type 1 NKT, and Helper T Cells

1 reference

12 December 2020

Co-accumulation of dendritic cells and natural killer T cells within rupture-prone regions in human atherosclerotic plaques

1 reference

12 December 2020

The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models

1 reference

12 December 2020

Induction of regulatory properties in dendritic cells by Valpha14 NKT cells

1 reference

12 December 2020

Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells

1 reference

12 December 2020

Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway

1 reference

12 December 2020

Invariant V(alpha)19i T cells regulate autoimmune inflammation

1 reference

12 December 2020

A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer

1 reference

12 December 2020

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator

1 reference

12 December 2020

Structure-guided design of an invariant natural killer T cell agonist for optimum protection from type 1 diabetes in non-obese diabetic mice

1 reference

12 December 2020

NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes

1 reference

12 December 2020

Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis

1 reference

12 December 2020

Psoriasis is mediated by a cutaneous defect triggered by activated immunocytes: induction of psoriasis by cells with natural killer receptors

1 reference

12 December 2020

Invariant NKT cells producing IL-4 or IL-10, but not IFN-gamma, inhibit the Th1 response in experimental autoimmune encephalomyelitis, whereas none of these cells inhibits the Th17 response

1 reference

12 December 2020

Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies

1 reference

12 December 2020

Prevention of diabetes in nonobese diabetic mice mediated by CD1d-restricted nonclassical NKT cells

1 reference

12 December 2020

Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice

1 reference

12 December 2020

Natural killer (NK) T cells are significantly decreased in the peripheral blood of patients with rheumatoid arthritis (RA)

1 reference

12 December 2020

Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy

1 reference

12 December 2020

NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

1 reference

12 December 2020

Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases

1 reference

12 December 2020

Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

1 reference

12 December 2020

CD1d-Restricted NKT Cells: An Interstrain Comparison

1 reference

12 December 2020

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

1 reference

12 December 2020

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

1 reference

12 December 2020

Accumulation of Valpha7.2-Jalpha33 invariant T cells in human autoimmune inflammatory lesions in the nervous system

1 reference

12 December 2020

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

1 reference

12 December 2020

Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161

1 reference

12 December 2020

Quantitative and Qualitative Differences in Proatherogenic NKT Cells in Apolipoprotein E–Deficient Mice

1 reference

12 December 2020

Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

1 reference

12 December 2020

Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of valpha14 natural killer T cells in mice

1 reference

12 December 2020

1 reference

12 December 2020

Activation of invariant natural killer T cells by synthetic glycolipid ligands suppresses autoantibody-induced arthritis

1 reference

12 December 2020

Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11

1 reference

12 December 2020

10.1111/J.1365-2249.2012.04625.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199318%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199318%20AND%20SRC:MED&resulttype=core&format=json