Tight junction-related human diseases (Q38077200)

28 August 2017

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Tight junction-related human diseases (English)

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28 August 2017

Norimasa Sawada

1

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28 August 2017

7 January 2013

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28 August 2017

Pathology International

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28 August 2017

63

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28 August 2017

1

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28 August 2017

1-12

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The tight junction: a multifunctional complex

28 August 2017

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Multifunctional strands in tight junctions

21 January 2018

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Claudin-based barrier in simple and stratified cellular sheets

21 January 2018

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Tight junction-based epithelial microenvironment and cell proliferation

21 January 2018

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Perspectives on tight junction research

21 January 2018

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Tight junctions and human diseases

21 January 2018

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Predicted expansion of the claudin multigene family

21 January 2018

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Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions

21 January 2018

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Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

21 January 2018

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Bves modulates epithelial integrity through an interaction at the tight junction

21 January 2018

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LSR defines cell corners for tricellular tight junction formation in epithelial cells

21 January 2018

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Manner of interaction of heterogeneous claudin species within and between tight junction strands

21 January 2018

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Claudins and epithelial paracellular transport

21 January 2018

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Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.

21 January 2018

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Pores in the wall: claudins constitute tight junction strands containing aqueous pores

21 January 2018

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Claudins create charge-selective channels in the paracellular pathway between epithelial cells

21 January 2018

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Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption

21 January 2018

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Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement

21 January 2018

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Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies

21 January 2018

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Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases

21 January 2018

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Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility

21 January 2018

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Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice

21 January 2018

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The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7

21 January 2018

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Occludin: a novel integral membrane protein localizing at tight junctions

21 January 2018

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Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions

21 January 2018

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Occludin and claudins in tight-junction strands: leading or supporting players?

21 January 2018

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Occludin: one protein, many forms

21 January 2018

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Down-regulation of survival signaling through MAPK and Akt in occludin-deficient mouse hepatocytes in vitro

21 January 2018

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Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes

21 January 2018

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c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells

21 January 2018

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Tricellulin is a tight-junction protein necessary for hearing

21 January 2018

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JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes

21 January 2018

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Junction adhesion molecule is a receptor for reovirus

21 January 2018

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The role of junctional adhesion molecules in vascular inflammation

21 January 2018

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Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties

21 January 2018

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ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.

21 January 2018

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

21 January 2018

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A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions

21 January 2018

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The PAR-aPKC system: lessons in polarity

21 January 2018

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Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells

21 January 2018

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Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization

21 January 2018

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The nuclear receptor hepatocyte nuclear factor 4alpha acts as a morphogen to induce the formation of microvilli

21 January 2018

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Regulation of epithelial permeability by the actin cytoskeleton

21 January 2018

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Uncoupling of gate and fence functions of MDCK cells by the actin-depolymerizing reagent mycalolide B.

21 January 2018

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Connexins induce and maintain tight junctions in epithelial cells

21 January 2018

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Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

21 January 2018

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Tight junctions and the regulation of gene expression

21 January 2018

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High-throughput mapping of a dynamic signaling network in mammalian cells

21 January 2018

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Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.

21 January 2018

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

21 January 2018

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HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis

21 January 2018

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External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers

21 January 2018

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Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells.

21 January 2018

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Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells

21 January 2018

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Activation of TLR2 enhances tight junction barrier in epidermal keratinocytes.

21 January 2018

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JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling

21 January 2018

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Occludin modulates transepithelial migration of neutrophils.

21 January 2018

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Dynamic migration of γδ intraepithelial lymphocytes requires occludin

21 January 2018

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Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency

21 January 2018

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Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo

21 January 2018

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Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein

21 January 2018

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Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.

21 January 2018

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Claudin-4-targeted therapy using Clostridium perfringens enterotoxin for prostate cancer

21 January 2018

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Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.

21 January 2018

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SS1 Helicobacter pylori disrupts the paracellular barrier of the gastric mucosa and leads to neutrophilic gastritis in mice

21 January 2018

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Distinct effects of Vibrio cholerae haemagglutinin/protease on the structure and localization of the tight junction-associated proteins occludin and ZO-1.

21 January 2018

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Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses

21 January 2018

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Calcium absorption across epithelia

21 January 2018

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Differential expression and subcellular localization of claudin-7, -8, -12, -13, and -15 along the mouse intestine

21 January 2018

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Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.

21 January 2018

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Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

21 January 2018

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Glial cell line-derived neurotrophic factor induces barrier function of endothelial cells forming the blood-brain barrier

21 January 2018

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Expression of receptors for glial cell line-derived neurotrophic factor (GDNF) and neurturin in the inner blood-retinal barrier of rats

21 January 2018

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Barrier function of microvessels and roles of glial cell line-derived neurotrophic factor in the rat testis

21 January 2018

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

21 January 2018

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Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes

21 January 2018

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Glial cell-derived cytokines attenuate the breakdown of vascular integrity in diabetic retinopathy

21 January 2018

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Intestinal mucosal barrier function in health and disease

21 January 2018

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Intestinal barrier function: molecular regulation and disease pathogenesis

21 January 2018

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Claudins in lung diseases

21 January 2018

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Epithelium dysfunction in asthma

21 January 2018

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Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases

21 January 2018

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Bacteria and host interactions in the gut epithelial barrier

21 January 2018

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Occludin expression decreases with the progression of human endometrial carcinoma.

21 January 2018

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Transcriptional regulation of cell polarity in EMT and cancer

21 January 2018

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Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations

21 January 2018

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Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail

21 January 2018

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Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells

21 January 2018

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Claudin family of proteins and cancer: an overview

21 January 2018

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Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

21 January 2018

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Crucial roles of Sp1 and epigenetic modifications in the regulation of the CLDN4 promoter in ovarian cancer cells

21 January 2018

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Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development

21 January 2018

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Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules, and cancer cells

21 January 2018

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Enhanced paracellular barrier function of rat mesothelial cells partially protects against cancer cell penetration

21 January 2018

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Drug targeting. Breaking down barriers.

21 January 2018

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Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model

21 January 2018

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Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids

21 January 2018

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Claudin-18 in biliary neoplasms. Its significance in the classification of intrahepatic cholangiocarcinoma.

21 January 2018

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New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.

21 January 2018

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Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer

21 January 2018

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Claudin-4: a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin.

21 January 2018

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Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells

21 January 2018

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Comparison of mucosal absorption-enhancing activity between a claudin-3/-4 binder and a broadly specific claudin binder

21 January 2018

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Uncoupling of the molecular 'fence' and paracellular 'gate' functions in epithelial tight junctions

21 January 2018

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Expression of GFRalpha-1, receptor for GDNF, in rat brain capillary during postnatal development of the BBB.

21 January 2018

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12 December 2020

The temporal and spatial vascular endothelial growth factor expression in retinal vasculogenesis of rat neonates

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12 December 2020

Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: a tight junction disease

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12 December 2020

VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly

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12 December 2020

Transmembrane proteins of tight junctions

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12 December 2020

Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells

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12 December 2020

Tight junction proteins and signal transduction pathways in hepatocytes

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12 December 2020

Activated T-lymphocytes express occludin, a component of tight junctions

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12 December 2020

Polarized distribution of carcinoembryonic antigen is associated with a tight junction molecule in human colorectal adenocarcinoma

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12 December 2020

ATP requirement for induced tight junction formation in HT 29 adenocarcinoma cells

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12 December 2020

Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. A potential mechanism for vascular permeability in diabetic retinopathy and tumors

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12 December 2020

Mammalian occludin in epithelial cells: its expression and subcellular distribution

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12 December 2020

The Role of Passive Transport in Calcium Absorption

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12 December 2020

The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice

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12 December 2020

Identifiers

DOI

10.1111/PIN.12021

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28 August 2017

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PubMed ID

23356220