Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development (Q38088523)

28 August 2017

Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development (English)

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28 August 2017

Karthik Sekar

2

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author name string

William A Rodríguez-Limas

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1

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PubMed ID

23481378

28 August 2017

Keith E J Tyo

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3

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28 August 2017

5 March 2013

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Current Opinion in Biotechnology

28 August 2017

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28 August 2017

24

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28 August 2017

6

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28 August 2017

1089-1093

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Phase I trial of an alhydrogel adjuvanted hepatitis B core virus-like particle containing epitopes of Plasmodium falciparum circumsporozoite protein

28 August 2017

1 reference

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Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV.

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Induction of insert-specific immune response in mice by hamster polyomavirus VP1 derived virus-like particles carrying LCMV GP33 CTL epitope

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The incorporation of the A2 protein to produce novel Qβ virus-like particles using cell-free protein synthesis.

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Efficient disulfide bond formation in virus-like particles

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Prevalence and phylogenetic analysis of the current porcine circovirus 2 genotypes after implementation of widespread vaccination programmes in the USA.

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Chimeric capsid protein as a nanocarrier for siRNA delivery: stability and cellular uptake of encapsulated siRNA.

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Development of a microRNA delivery system based on bacteriophage MS2 virus-like particles

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An engineered eukaryotic protein glycosylation pathway in Escherichia coli.

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Chimeric hepatitis E virus-like particle as a carrier for oral-delivery

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Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry

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P22 viral capsids as nanocomposite high-relaxivity MRI contrast agents

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Heterologous expression of the modified coat protein of Cowpea chlorotic mottle bromovirus results in the assembly of protein cages with altered architectures and function

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Cell-free synthetic biology: thinking outside the cell

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Glycosylation engineering in yeast: the advent of fully humanized yeast

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Virus-like particles as a vaccine delivery system: myths and facts

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Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis

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Vaccine potential of Nipah virus-like particles

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Murine polyomavirus virus-like particles carrying full-length human PSA protect BALB/c mice from outgrowth of a PSA expressing tumor

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Cell-free protein synthesis: applications come of age.

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Molecular and process design for rotavirus-like particle production in Saccharomyces cerevisiae

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Engineering of vesicle trafficking improves heterologous protein secretion in Saccharomyces cerevisiae

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Hepatitis B virus core particles displaying Mycobacterium tuberculosis antigen ESAT-6 enhance ESAT-6-specific immune responses

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On the effect of thermodynamic equilibrium on the assembly efficiency of complex multi-layered virus-like particles (VLP): the case of rotavirus VLP.

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Chimeric calicivirus-like particles elicit specific immune responses in pigs.

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Nanoreactors by programmed enzyme encapsulation inside the capsid of the bacteriophage P22

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The use of recombinant pseudotype virus-like particles harbouring inserted target antigen to generate antibodies against cellular marker p16INK4A.

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Pre-expression of a sulfhydryl oxidase significantly increases the yields of eukaryotic disulfide bond containing proteins expressed in the cytoplasm of E.coli

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Escherichia coli-based cell-free synthesis of virus-like particles.

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The structure of hepadnaviral core antigens. Identification of free thiols and determination of the disulfide bonding pattern

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Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity

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A microbial platform for rapid and low-cost virus-like particle and capsomere vaccines.

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Chimeric Hepatitis B core antigen virus-like particles displaying the envelope domain III of dengue virus type 2.

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Human papillomavirus (HPV) type distribution and serological response to HPV type 6 virus-like particles in patients with genital warts

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Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles

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Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases.

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Construction and characterization of virus-like particles: a review

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M2e-based universal influenza A vaccine

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Use of hepadnavirus core proteins as vaccine platforms

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Hepatitis E vaccine debuts.

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Biopharmaceutical benchmarks 2010

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Virus-like particles of hepatitis B virus core protein containing five mimotopes of infectious bursal disease virus (IBDV) protect chickens against IBDV.

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Vaccination with dengue virus-like particles induces humoral and cellular immune responses in mice

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12 December 2020

Clathrin-mediated endocytosis and lysosomal cleavage of hepatitis B virus capsid-like core particles

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Virus-based nanocarriers for drug delivery

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Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial

1 reference

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An optimized yeast cell-free system: sufficient for translation of human papillomavirus 58 L1 mRNA and assembly of virus-like particles

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12 December 2020

10.1016/J.COPBIO.2013.02.008

Identifiers

DOI

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28 August 2017

0 references

1 reference

PubMed ID

23481378