Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41. (Q45357217)

13 December 2017

Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41. (English)

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13 December 2017

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C Pastori

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D Tudor

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L Diomede

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A S Drillet

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A Jegerlehner

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T A Röhn

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13 December 2017

language of work or name

English

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publication date

2 June 2012

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431

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1-2

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Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection

13 December 2017

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Neutralizing antiviral B cell responses

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Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

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Direct antibody access to the HIV-1 membrane-proximal external region positively correlates with neutralization sensitivity

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Mutilation of RNA phage Qbeta virus-like particles: from icosahedrons to rods

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Serum IgA of HIV-exposed uninfected individuals inhibit HIV through recognition of a region within the alpha-helix of gp41.

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Passively transmitted gp41 antibodies in babies born from HIV-1 subtype C-seropositive women: correlation between fine specificity and protection.

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Role of repetitive antigen patterns for induction of antibodies against antibodies

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Potent cross-group neutralization of primary human immunodeficiency virus isolates with monoclonal antibodies--implications for acquired immunodeficiency syndrome vaccine

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Vaccines that facilitate antigen entry into dendritic cells.

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Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection

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Maternal HIV-1 antibody and vertical transmission in subtype C virus infection

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Multiple tandem copies of conserved gp41 epitopes incorporated in gag virus-like particles elicit systemic and mucosal antibodies in an optimized heterologous vector delivery regimen

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The gp41 epitope, QARVLAVERY, is highly conserved and a potent inducer of IgA that neutralizes HIV-1 and inhibits viral transcytosis

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TLR9 signaling in B cells determines class switch recombination to IgG2a

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Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection

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Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120.

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Nucleotide sequence of a ssRNA phage from Acinetobacter: kinship to coliphages

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Native display of complete foreign protein domains on the surface of hepatitis B virus capsids.

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Maternal antibody response at delivery and perinatal transmission of human immunodeficiency virus type 1 in African women

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Rational design of a stable, freeze-dried virus-like particle-based vaccine formulation

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The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter

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Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies

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Specificity of the autologous neutralizing antibody response

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Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

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Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting

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A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain

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Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection

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Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways

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Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies

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A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice

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Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles

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Versatile virus-like particle carrier for epitope based vaccines

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The broadly neutralizing HIV-1 IgG 2F5 elicits gp41-specific antibody-dependent cell cytotoxicity in a FcγRI-dependent manner.

7 January 2021

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HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis

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Cryo electron microscopy reconstructions of the Leviviridae unveil the densest icosahedral RNA packing possible.

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Prime boost vaccination approaches with different conjugates of a new HIV-1 gp41 epitope encompassing the membrane proximal external region induce neutralizing antibodies in mice

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Distribution and three-dimensional structure of AIDS virus envelope spikes

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.05.005

10.1016/J.VIROL.2012.05.005

7 January 2021

Identifiers

DOI

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13 December 2017

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