Polyethylenimines for siRNA and miRNA delivery in vivo (Q38110474)

29 August 2017

Polyethylenimines for siRNA and miRNA delivery in vivo (English)

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29 August 2017

2

Achim Aigner

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29 August 2017

Sabrina Höbel

1

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29 August 2017

29 May 2013

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Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

29 August 2017

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29 August 2017

5

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29 August 2017

484-501

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29 August 2017

5

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Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

29 August 2017

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

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MicroRNAs (miRNAs) in cancer invasion and metastasis: therapeutic approaches based on metastasis-related miRNAs

21 January 2018

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Repression of protein synthesis by miRNAs: how many mechanisms?

21 January 2018

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Design and gene delivery activity of modified polyethylenimines.

21 January 2018

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Branched and linear poly(ethylene imine)-based conjugates: synthetic modification, characterization, and application

21 January 2018

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Synthesis of linear polyethylenimine derivatives for DNA transfection

21 January 2018

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

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Nonviral vectors for gene delivery

21 January 2018

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Breaking up the correlation between efficacy and toxicity for nonviral gene delivery

21 January 2018

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A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity

21 January 2018

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A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes

21 January 2018

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Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

21 January 2018

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Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

21 January 2018

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A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine

21 January 2018

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Polyethylenimine-based intravenous delivery of transgenes to mouse lung.

21 January 2018

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Side-effects of a systemic injection of linear polyethylenimine-DNA complexes

21 January 2018

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Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice.

21 January 2018

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Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung

21 January 2018

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Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma

21 January 2018

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In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes

21 January 2018

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Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance.

21 January 2018

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Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes

21 January 2018

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

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A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA.

21 January 2018

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Target specific intracellular delivery of siRNA/PEI-HA complex by receptor mediated endocytosis.

21 January 2018

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Liver-targeted siRNA delivery by polyethylenimine (PEI)-pullulan carrier.

21 January 2018

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Poly(I:C)-mediated tumor growth suppression in EGF-receptor overexpressing tumors using EGF-polyethylene glycol-linear polyethylenimine as carrier

21 January 2018

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An MRI-visible non-viral vector for targeted Bcl-2 siRNA delivery to neuroblastoma

21 January 2018

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The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine

21 January 2018

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Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon.

21 January 2018

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Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice

21 January 2018

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Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo

21 January 2018

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Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers

21 January 2018

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Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy

21 January 2018

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Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer

21 January 2018

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Injectable polyplex hydrogel for localized and long-term delivery of siRNA.

21 January 2018

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Intra-articular controlled release of anti-inflammatory siRNA with biodegradable polymer microparticles ameliorates temporomandibular joint inflammation

21 January 2018

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Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice

21 January 2018

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Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes

21 January 2018

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Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery

21 January 2018

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Pegylation: a novel process for modifying pharmacokinetics

21 January 2018

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EGFR-homing dsRNA activates cancer-targeted immune response and eliminates disseminated EGFR-overexpressing tumors in mice

21 January 2018

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Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer

21 January 2018

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Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expression

21 January 2018

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Inhibition of influenza virus production in virus-infected mice by RNA interference

21 January 2018

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RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

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Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference

21 January 2018

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RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenografts.

21 January 2018

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RNA interference targeting hypoxia inducible factor 1alpha reduces post-operative adhesions in rats.

21 January 2018

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Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice.

21 January 2018

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Acute inhibition of guanosine triphosphate cyclohydrolase 1 uncouples endothelial nitric oxide synthase and elevates blood pressure

21 January 2018

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TMEM16A confers receptor-activated calcium-dependent chloride conductance

21 January 2018

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Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation

21 January 2018

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Gadd45beta is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia

21 January 2018

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Down-regulation of Toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat model

21 January 2018

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miR-22 represses cancer progression by inducing cellular senescence

21 January 2018

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Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata

21 January 2018

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MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma

21 January 2018

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RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

21 January 2018

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Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination

21 January 2018

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A small interfering RNA targeting the KLF6 splice variant, KLF6-SV1, as gene therapy for gastric cancer

21 January 2018

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The proto-oncogene Pim-1 is a target of miR-33a

21 January 2018

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Nonviral Gene Delivery to the Rat Kidney with Polyethylenimine

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WNAN.1228

1 reference

29 August 2017

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PubMed ID

23720168