Argonaute and GW182 proteins: an effective alliance in gene silencing (Q38122217)

29 August 2017

title

Argonaute and GW182 proteins: an effective alliance in gene silencing (English)

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29 August 2017

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Janina Pfaff

1

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29 August 2017

Gunter Meister

series ordinal

2

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29 August 2017

publication date

1 August 2013

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Biochemical Society Transactions

29 August 2017

published in

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29 August 2017

volume

41

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29 August 2017

issue

4

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29 August 2017

page(s)

855-860

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Mechanisms of gene silencing by double-stranded RNA

29 August 2017

cites work

1 reference

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Argonaute proteins at a glance

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PIWI-interacting small RNAs: the vanguard of genome defence

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Slicer and the argonautes

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Argonaute2 is the catalytic engine of mammalian RNAi

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

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Eukaryotic Argonautes come into focus

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

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Turning catalytically inactive human Argonaute proteins into active slicer enzymes.

21 January 2018

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A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

21 January 2018

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The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

21 January 2018

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Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

21 January 2018

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The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans

21 January 2018

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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

21 January 2018

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

21 January 2018

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Disruption of GW bodies impairs mammalian RNA interference

21 January 2018

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Identification of novel argonaute-associated proteins

21 January 2018

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

21 January 2018

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21 January 2018

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RNA recognition motifs: boring? Not quite

21 January 2018

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The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing

21 January 2018

1 reference

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mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

21 January 2018

1 reference

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The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins

21 January 2018

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miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs

21 January 2018

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Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

21 January 2018

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GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

21 January 2018

1 reference

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miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

21 January 2018

1 reference

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Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

21 January 2018

1 reference

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A C-terminal silencing domain in GW182 is essential for miRNA function

21 January 2018

1 reference

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The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

21 January 2018

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A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation

21 January 2018

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21 January 2018

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21 January 2018

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Functional dissection of the human TNRC6 (GW182-related) family of proteins

21 January 2018

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Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

21 January 2018

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Agos--a universal web tool for GW Argonaute-binding domain prediction.

21 January 2018

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RNAi-mediated targeting of heterochromatin by the RITS complex

21 January 2018

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Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin.

21 January 2018

1 reference

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The diversity of RNA silencing pathways in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

An effector of RNA-directed DNA methylation in arabidopsis is an ARGONAUTE 4- and RNA-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

Two GW repeat proteins interact with Tetrahymena thermophila argonaute and promote genome rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

Viral protein inhibits RISC activity by argonaute binding through conserved WG/GW motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20130047

21 January 2018

Identifiers

DOI

10.1042/BST20130047

1 reference

29 August 2017

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